Abstract
Background and Aims
Nephrology is a medical specialty, which in the last 50 years experienced very important scientific developments, which formally revolutionized clinical practice, namely renal biopsy, renal replacement therapy and transplantation. In addition understanding pathogenesis and clinic of renal disease also improves steadily, resulting in renewal of definitions, classifications and therapeutics in nephrology. In this context publications with nephrological content are also expanding. The aim of this bibliography-study was to analyze the publications, related to nephrology specific keywords, as they appear in the PubMed database.
Method
Certain nephrology related keywords were applied: “nephrology”, “acute renal failure”, “renal biopsy”, “hemodialysis”, “peritoneal dialysis” and “renal transplantation” were applied as terms in PubMed. Instead of renal kidney was used as an alternative term.
Results
Nephrology as a term appears 141573 times in the database and beginning from 1946 its appearance is expanding in the last three decades. The term “acute renal failure” is found for the time in 1932 in one publication and in a total number 92278 of publications. Renal biopsy appears from 1943 in a total number of 15506 publications. Hemodialysis appears in 182730 citations for the first time in 1915 in human application. Peritoneal dialysis appears in 32266 citations for the first time in 1901 and 1946 in human application. One publication on renal transplantation appears in 1946 and the total number of publications related to renal transplantation is 106075.
Conclusion
According to the above findings there is a clear expansion of nephrological publications in the last decades. In addition, hemodialysis remains still the most frequent term used in nephrology related publications. Historical analysis the PubMed database is very useful as a tool to understand the research and publication trends in nephrology, as we approach to the new era of precision medicine.