The association of potentially inappropriate medication use on health outcomes and hospital costs in community-dwelling older persons: a longitudinal 12-year study

2018 ◽  
Vol 20 (2) ◽  
pp. 233-243 ◽  
Author(s):  
Virva Hyttinen ◽  
Johanna Jyrkkä ◽  
Leena K. Saastamoinen ◽  
Anna-Kaisa Vartiainen ◽  
Hannu Valtonen
2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Mohsen Bazargan ◽  
James Smith ◽  
Masoud Movassaghi ◽  
David Martins ◽  
Hamed Yazdanshenas ◽  
...  

The purpose of the present study was to examine correlates of polypharmacy among underserved community-dwelling older African American adults. Methods. This study recruited 400 underserved older African Americans adults living in South Los Angeles. The structured face-to-face interviews collected data on participants’ characteristics and elicited data pertaining to the type, frequency, dosage, and indications of all medications used by participants. Results. Seventy-five and thirty percent of participants take at least five and ten medications per day, respectively. Thirty-eight percent of participants received prescription medications from at least three providers. Inappropriate drug use occurred among seventy percent of the participants. Multivariate analysis showed that number of providers was the strongest correlate of polypharmacy. Moreover, data show that gender, comorbidity, and potentially inappropriate medication use are other major correlates of polypharmacy. Conclusions. This study shows a high rate of polypharmacy and potentially inappropriate medication use among underserved older African American adults. We documented strong associations between polypharmacy and use of potentially inappropriate medications, comorbidities, and having multiple providers. Polypharmacy and potentially inappropriate medications may be attributed to poor coordination and management of medications among providers and pharmacists. There is an urgent need to develop innovative and effective strategies to reduce inappropriate polypharmacy and potentially inappropriate medication in underserved elderly minority populations.


JAMA ◽  
2001 ◽  
Vol 286 (22) ◽  
pp. 2823 ◽  
Author(s):  
Chunliu Zhan ◽  
Judith Sangl ◽  
Arlene S. Bierman ◽  
Marlene R. Miller ◽  
Bruce Friedman ◽  
...  

Medical Care ◽  
2007 ◽  
Vol 45 (5) ◽  
pp. 472-476 ◽  
Author(s):  
Alex Z. Fu ◽  
Jenny Z. Jiang ◽  
Jaxk H. Reeves ◽  
Jack E. Fincham ◽  
Gordon G. Liu ◽  
...  

2010 ◽  
Vol 24 (1) ◽  
pp. 56-63 ◽  
Author(s):  
Denys T. Lau ◽  
Nathaniel D. Mercaldo ◽  
Andrew T. Harris ◽  
Emily Trittschuh ◽  
Joseph Shega ◽  
...  

2016 ◽  
Vol 52 (4) ◽  
pp. 1534-1549 ◽  
Author(s):  
G. Edward Miller ◽  
Eric M. Sarpong ◽  
Amy J. Davidoff ◽  
Eunice Y. Yang ◽  
Nicole J. Brandt ◽  
...  

2019 ◽  
Vol 28 (21-22) ◽  
pp. 3914-3922 ◽  
Author(s):  
Alisson Fernandes Bolina ◽  
Nayara Cândida Gomes ◽  
Gianna Fiori Marchiori ◽  
Maycon Sousa Pegorari ◽  
Darlene Mara dos Santos Tavares

2004 ◽  
Vol 60 (11) ◽  
pp. 813-819 ◽  
Author(s):  
Nathalie Lechevallier-Michel ◽  
Marion Gautier-Bertrand ◽  
Annick Alp�rovitch ◽  
Claudine Berr ◽  
Jo�l Belmin ◽  
...  

2013 ◽  
Vol 5 (3) ◽  
pp. 182 ◽  
Author(s):  
Daphne Lee ◽  
Nataly Martini ◽  
Simon Moyes ◽  
Karen Hayman ◽  
Monica Zolezzi ◽  
...  

INTRODUCTION: The ageing population means prescribing for chronic illnesses in older people is expected to rise. Comorbidities and compromised organ function may complicate prescribing and increase medication-related risks. Comorbid depression in older people is highly prevalent and complicates medication prescribing decisions. AIM: To determine the prevalence of potentially inappropriate medication use in a community-dwelling population of older adults with depressive symptoms. METHODS: The medications of 191 community-dwelling older people selected because of depressive symptoms for a randomised trial were reviewed and assessed using the modified version of the Beers’ Criteria. The association between inappropriate medication use and various population characteristics was assessed using Chi-square statistics and logistic regression analyses. RESULTS: The mean age was 81 (±4.3) years and 59% were women. The median number of medications used was 6 (range 1–21 medications). The most commonly prescribed potentially inappropriate medications were amitriptyline, dextropropoxyphene, quinine and benzodiazepines. Almost half (49%) of the participants were prescribed at least one potentially inappropriate medication; 29% were considered to suffer significant depressive symptoms (Geriatric Depression Scale =5) and no differences were found in the number of inappropriate medications used between those with and without significant depressive symptoms (Chi-square 0.005 p=0.54). DISCUSSION: Potentially inappropriate medication use, as per the modified Beers’ Criteria, is very common among community-dwelling older people with depressive symptoms. However, the utility of the Beers’ Criteria is lessened by lack of clinical correlation. Ongoing research to examine outcomes related to apparent inappropriate medication use is needed. KEYWORDS: Depression; depressive symptoms; inappropriate prescribing; older adults


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