As part of the multidisciplinary management of pediatric chronic pain, interventional pain-management (IPM) techniques can play an important role when pain is unrelieved by conventional treatment modalities. Many procedures and indications are extrapolated from adult studies, and evidence for long-term efficacy in pediatric populations is limited. Interventions range from injection techniques with local anesthetic and/or corticosteroids to neuraxial blockade with implanted catheters. In selected patients, IPM procedures can serve as useful adjuncts in multidisciplinary management of chronic pain disorders.