No Apparent Association Between Ocular Perfusion Pressure and Visual Field Damage in Normal-Tension Glaucoma Patients

2006 ◽  
Vol 50 (6) ◽  
pp. 547-549 ◽  
Author(s):  
Naoyuki Kurita ◽  
Atsuo Tomidokoro ◽  
Chihiro Mayama ◽  
Makoto Aihara ◽  
Makoto Araie
Keyword(s):  
Visual Field ◽  
Perfusion Pressure ◽  
Normal Tension Glaucoma ◽  
Ocular Perfusion Pressure ◽  
Ocular Perfusion ◽  
Visual Field Damage ◽  
Apparent Association

scholarly journals Factors Related to a Right-Left Difference in Visual Field Defect in the Eyes with Untreated Normal Tension Glaucoma

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Haruka Moroi ◽  
Ayako Anraku ◽  
Kyoko Ishida ◽  
Goji Tomita
Keyword(s):  
Visual Field ◽  
Visual Field Defect ◽  
Central Corneal Thickness ◽  
Perfusion Pressure ◽  
Corneal Thickness ◽  
Normal Tension Glaucoma ◽  
Spherical Equivalent ◽  
Ocular Perfusion Pressure ◽  
Ocular Perfusion ◽  
Field Defect

Purpose. To investigate factors related to a right-left difference in visual field defect in untreated normal tension glaucoma (NTG). Methods. The medical records of 92 patients with untreated NTG were reviewed. Ocular blood flow was evaluated with laser speckle flowgraphy, and the mean blur rate (MBR) at the optic nerve head was analyzed. Relationships between right-left differences in mean deviation (MD), intraocular pressure, MBR, spherical equivalent, central corneal thickness, and mean ocular perfusion pressure were evaluated using Spearman’s rank correlation coefficient. Multiple regression analysis was used to detect factors contributing to a right-left difference in MD. Results. The right-left difference in MD was correlated with differences in intraocular pressure (r=−0.263, P=0.011), MBR (r=0.417, P<0.001), and spherical equivalent (r=0.213, P=0.042), but not with central corneal thickness or mean ocular perfusion pressure. Multiple regression analysis showed that a difference in MBR was the only significant contributor to a right-left difference in MD (slope 0.047, 95% confidence interval 0.025–0.069; P<0.001). Conclusion. In untreated NTG, a difference in blood flow at the optic nerve head was a significant contributor to a right-left difference in visual field defect.

scholarly journals Correlation between ocular perfusion pressure and estimated translamina cribrosa pressure difference in healthy young adults

Biomedicine ◽  
2020 ◽  
Vol 39 (2) ◽  
pp. 326-332
Author(s):  
Ramya Channarayapatna Madhusetty ◽  
Rajalakshmi Ramashetty ◽  
Mamatha Sunaganahalli Dyapegowda
Keyword(s):  
Young Adults ◽  
Pressure Difference ◽  
Perfusion Pressure ◽  
Fluid Pressure ◽  
Normal Tension Glaucoma ◽  
Lamina Cribrosa ◽  
Ocular Perfusion Pressure ◽  
Medical College ◽  
Ocular Perfusion ◽  
Significant Difference

Introduction and Aim: Glaucoma is a chronic optic neuropathy which is the leading cause of irreversible blindness across the globe. It is known that Intraocular pressure is responsible for these altered changes but recent experimental and clinical studies have reported that cerebrospinal fluid pressure (CSFP) and trans-lamina cribrosa pressure difference (TLCPD), may be an important cause of glaucomatous optic nerve damage, especially in subjects with normal-tension glaucoma. To assess the correlation between ocular perfusion pressure (OPP) and TLCPD in healthy young adults. Materials and Methods: One hundred healthy young adult volunteers comprising of 50 obese (25 males and 25 females) and 50 non-obese (25 males and 25 females) in the age group of 18-19 years among MBBS Phase I students of JSS Medical College, JSSU, Mysore were the subjects for the study. Blood Pressure and Intra Ocular Pressure were recorded. Mean arterial pressure (MAP), OPP, CSFPand TLCPD were calculated. Results: There exists a positive correlation (0.50) between OPP and TLCPD. There was a statistically significant difference in OPP, CSFP and TLCPD between obese and non-obese groups. Conclusion: The present study provides information on the relationship of TLCPD with CSFP and OPP that are higher in obese individuals.  

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