Effect of culture temperature on TNFR-Fc productivity in recombinant glutamine synthetase-chinese hamster ovary cells

Biotechnology Letters ◽

10.1007/s10529-010-0318-5 ◽

2010 ◽

Vol 32 (9) ◽

pp. 1239-1244 ◽

Author(s):

Li Fan ◽

Liang Zhao ◽

Zhaoyang Ye ◽

Yating Sun ◽

Tianci Kou ◽

...

Keyword(s):

Glutamine Synthetase ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Culture Temperature ◽

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High Level Expression of Tissue Inhibitor of Metalloproteinases in Chinese Hamster Ovary Cells Using Glutamine Synthetase Gene Amplification

Nature Biotechnology ◽

10.1038/nbt0790-662 ◽

1990 ◽

Vol 8 (7) ◽

pp. 662-667 ◽

Author(s):

M. I. Cockett ◽

C. R. Bebbington ◽

G. T. Yarranton

Keyword(s):

Glutamine Synthetase ◽

Gene Amplification ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Tissue Inhibitor Of Metalloproteinases ◽

High Level Expression ◽

Tissue Inhibitor ◽

Ovary Cells ◽

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Glutamine Synthetase Gene Amplification in Chinese Hamster Ovary Cells

Gene Amplification in Mammalian Cells ◽

10.1201/9781003066989-27 ◽

2020 ◽

pp. 301-312

Author(s):

Richard H. Wilson

Keyword(s):

Glutamine Synthetase ◽

Gene Amplification ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Ovary Cells ◽

Glutamine Synthetase Gene

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Adaptation of Chinese hamster ovary cells to low culture temperature: Cell growth and recombinant protein production

Journal of Biotechnology ◽

10.1016/j.jbiotec.2005.09.010 ◽

2006 ◽

Vol 122 (4) ◽

pp. 463-472 ◽

Author(s):

Sung Kwan Yoon ◽

Jong Kwang Hong ◽

Seung Ho Choo ◽

Ji Yong Song ◽

Hong Woo Park ◽

...

Keyword(s):

Cell Growth ◽

Recombinant Protein ◽

Chinese Hamster Ovary ◽

Recombinant Protein Production ◽

Protein Production ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Culture Temperature ◽

Ovary Cells ◽

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Effect of Low Culture Temperature on Specific Productivity and Transcription Level of Anti-4-1BB Antibody in Recombinant Chinese Hamster Ovary Cells

Biotechnology Progress ◽

10.1021/bp034051m ◽

2008 ◽

Vol 19 (4) ◽

pp. 1383-1386 ◽

Author(s):

Sung Kwan Yoon ◽

Sung Hyun Kim ◽

Gyun Min Lee

Keyword(s):

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Specific Productivity ◽

Culture Temperature ◽

Transcription Level ◽

Ovary Cells ◽

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Enhancing Effect of Low Culture Temperature on Specific Antibody Productivity of Recombinant Chinese Hamster Ovary Cells: Clonal Variation

Biotechnology Progress ◽

10.1021/bp049847f ◽

2004 ◽

Vol 20 (6) ◽

pp. 1683-1688 ◽

Author(s):

S.K. Yoon ◽

S.O. Hwang ◽

G.M. Lee

Keyword(s):

Specific Antibody ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Clonal Variation ◽

Culture Temperature ◽

Ovary Cells ◽

Enhancing Effect ◽

Antibody Productivity ◽

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Limitations to the Development of Humanized Antibody Producing Chinese Hamster Ovary Cells Using Glutamine Synthetase-Mediated Gene Amplification

Biotechnology Progress ◽

10.1021/bp060004t ◽

2006 ◽

Vol 22 (3) ◽

pp. 770-780 ◽

Author(s):

S.C. Jun ◽

M.S. Kim ◽

H.J. Hong ◽

G.M. Lee

Keyword(s):

Glutamine Synthetase ◽

Gene Amplification ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Ovary Cells ◽

Humanized Antibody

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Metabolic characteristics of recombinant Chinese hamster ovary cells expressing glutamine synthetase in presence and absence of glutamine

Cytotechnology ◽

10.1007/s10616-006-9010-y ◽

2006 ◽

Vol 51 (1) ◽

pp. 21-28 ◽

Author(s):

Fang Zhang ◽

Xiangming Sun ◽

Xiaoping Yi ◽

Yuanxing Zhang

Keyword(s):

Glutamine Synthetase ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Ovary Cells ◽

Metabolic Characteristics ◽

Presence And Absence

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Superfluous glutamine synthetase activity in Chinese Hamster Ovary cells selected under glutamine limitation is growth limiting in glutamine‐replete conditions and can be inhibited by serine

Biotechnology Progress ◽

10.1002/btpr.2856 ◽

2019 ◽

Vol 35 (5) ◽

Author(s):

Vishwanathgouda Maralingannavar ◽

Dharmeshkumar Parmar ◽

Venkateswarlu Panchagnula ◽

Mugdha Gadgil

Keyword(s):

Glutamine Synthetase ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Synthetase Activity ◽

Glutamine Synthetase Activity ◽

Ovary Cells ◽

Glutamine Limitation

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Detailed understanding of enhanced specific productivity in Chinese hamster ovary cells at low culture temperature

Journal of Bioscience and Bioengineering ◽

10.1016/j.jbiosc.2010.11.016 ◽

2011 ◽

Vol 111 (3) ◽

pp. 365-369 ◽

Author(s):

Tian-Ci Kou ◽

Li Fan ◽

Yan Zhou ◽

Zhao-Yang Ye ◽

Xu-Ping Liu ◽

...

Keyword(s):

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Specific Productivity ◽

Culture Temperature ◽

Detailed Understanding ◽

Ovary Cells ◽

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Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system

Protein Engineering Design and Selection ◽

10.1093/protein/10.12.1465 ◽

1997 ◽

Vol 10 (12) ◽

pp. 1465-1473 ◽

Author(s):

T. C. Blochberger ◽

C. Cooper ◽

D. Peretz ◽

J. Tatzelt ◽

O. H. Griffith ◽

...

Keyword(s):

Glutamine Synthetase ◽

Protein Expression ◽

Prion Protein ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Ovary Cells ◽

Amplification System

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