scholarly journals Validity of resting strain/strain rate in prediction of myocardial viability

Author(s):  
Amr Hanafy ◽  
Soliman Ghareb Ibrahim ◽  
Hossam-Eldein Mohamed Mohamed Mansour ◽  
Aml Mohamed Soliman ◽  
Mohamed Kamal Salama
Circulation ◽  
2005 ◽  
Vol 112 (25) ◽  
pp. 3892-3900 ◽  
Author(s):  
Lizelle Hanekom ◽  
Carly Jenkins ◽  
Leanne Jeffries ◽  
Colin Case ◽  
Julie Mundy ◽  
...  

2006 ◽  
Vol 290 (2) ◽  
pp. H724-H731 ◽  
Author(s):  
Tae-Ho Park ◽  
Sherif F. Nagueh ◽  
Dirar S. Khoury ◽  
Helen A. Kopelen ◽  
Spyridon Akrivakis ◽  
...  

We sought to assess the role of regional diastolic function by Doppler echocardiography in predicting myocardial viability. Sixteen dogs underwent left anterior descending coronary artery ( n = 8) or circumflex ( n = 8) occlusion. All animals were imaged at baseline and 1–8 wk postinfarction (post-MI). In 10 dogs, invasive hemodynamic monitoring with a conductance catheter placed in the left ventricle (LV) was performed at the above time points. Dobutamine was infused at 1–8 wk post-MI to determine LV contractile reserve. Histomorphological analysis was performed to determine the presence of viable myocardium and changes in interstitial matrix. Post-MI, diastolic strain rate measurements (in radial and longitudinal planes) decreased significantly in the distribution of the diseased artery ( P < 0.01) and on multiple regression analysis were determined by time constant of LV relaxation, end-diastolic pressure, regional stiffness, and the ratio of cellular infiltration to collagen deposition in the interstitial matrix. Among several indexes, diastolic strain rate during dobutamine infusion readily identified segments with >20% transmural infarction and related best to the extent of interstitial fibrosis ( r = −0.86, P < 0.01). In an animal model of healing canine infarcts, diastolic strain rate by Doppler echocardiography appears to be a promising novel index of myocardial viability.


2021 ◽  
Author(s):  
Amr Hanafy ◽  
Soliman Ghareb Ibrahim ◽  
Hossam Eldein Mohamed Mohamed Mansour ◽  
Aml Mohamed Soliman ◽  
Mohamed Kamal Salama

Abstract PurposeTo evaluate the validity of the resting strain/strain rate measurements in predicting myocardial viability taking delayed enhancement cardiac magnetic resonance imaging as the gold standard. Methods: A cohort of 60 patients at three months followed up after acute myocardial infarction were recruited for this study. Resting echocardiography with offline analysis of deformation indices and gadolinium contrast enhanced cardiac magnetic resonance imaging were applied for all patients. ResultsFor the final assessment, 268 segments with significant resting wall motion abnormalities were presented. Resting longitudinal strain was significantly (p<0.05) higher in viable, compared with non-viable segments in all the studied individual myocardial segments (apical inferior, mid antro-lateral, mid-inferolateral, mid infero-septum, and all other segments). Likewise, resting longitudinal strain rate was significantly (p<0.05) higher in viable, compared with non-viable segments in almost all studied individual myocardial segments apart from apical inferior, mid inferolateral and basal antro-septum (p=0.245, p=0.098, p=0.097 respectively). ConclusionResting Strain and Resting Strain rate could be used as accurate predictors of myocardia viability following acute myocardial infarction.


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