The main objective of this study was to analyze local perceptions of climate variability and the different adaptation strategies of four communities in the southern Yucatán Peninsula, using the Social-Ecological System (SES) approach. Four SESs were considered: two in the coastal zone and two in the tropical forest zone. Data were collected using different qualitative methodological tools (interviews, participant observation, and focal groups) and the information collected from each site was triangulated. In all four sites, changes in climate variability were perceived as “less rain and more heat”. In the tropical forest (or Maya) zone, an ancestral indigenous weather forecasting system, known as “Xook k’íin” (or “las cabañuelas”), was recorded and the main activity affected by climate variability was found to be slash-and burn farming or the milpa. In the coastal zone, the main activities affected are fishing and tourism. In all the cases analyzed, local climate change adaptation strategies include undertaking alternative work, and changing the calendar of daily, seasonal and annual labor and seasonal migration. The population of all four SESs displayed concern and uncertainty as regards dealing with these changes and possible changes in the future.