Impairment by 5-Fluorouracil of the Healing of Gastric Lesions in Rats: Effect of Lafutidine, a Histamine H2 Receptor Antagonist, Mediated by Capsaicin-Sensitive Afferent Neurons

Yukiko Murashima; Tohru Kotani; Shusaku Hayashi; Yoshino Komatsu; Akari Nakagiri; Kikuko Amagase; Koji Takeuchi

doi:10.1007/s10620-008-0325-8

Impairment by 5-Fluorouracil of the Healing of Gastric Lesions in Rats: Effect of Lafutidine, a Histamine H2 Receptor Antagonist, Mediated by Capsaicin-Sensitive Afferent Neurons

Digestive Diseases and Sciences ◽

10.1007/s10620-008-0325-8 ◽

2008 ◽

Vol 54 (1) ◽

pp. 36-45 ◽

Cited By ~ 1

Author(s):

Yukiko Murashima ◽

Tohru Kotani ◽

Shusaku Hayashi ◽

Yoshino Komatsu ◽

Akari Nakagiri ◽

...

Keyword(s):

Receptor Antagonist ◽

Afferent Neurons ◽

Gastric Lesions ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Unique Profile of Lafutidine, A Novel Histamine H2-Receptor Antagonist - Mucosal Protection Throughout Gastrointestinal Tract Mediated by Capsaicin-Sensitive Afferent Neurons -

Drug Design Reviews - Online ◽

10.2174/1567269043480681 ◽

2004 ◽

Vol 1 (2) ◽

pp. 133-144 ◽

Cited By ~ 4

Author(s):

Sadayoshi Onodera ◽

Kayoko Nishida ◽

Koji Takeuchi

Keyword(s):

Gastrointestinal Tract ◽

Receptor Antagonist ◽

Mucosal Protection ◽

Afferent Neurons ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Effect of BMY-25368, a potent and long-acting histamine H2-receptor antagonist, on gastric secretion and aspirin-induced gastric lesions in the dog

Alimentary Pharmacology & Therapeutics ◽

10.1111/j.1365-2036.1989.tb00217.x ◽

2007 ◽

Vol 3 (3) ◽

pp. 299-313 ◽

Cited By ~ 5

Author(s):

R. L. CAVANAGH ◽

J. P. BUYNISKI

Keyword(s):

Gastric Secretion ◽

Receptor Antagonist ◽

Gastric Lesions ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Long Acting ◽

Histamine H2 Receptor Antagonist

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Effect of lafutidine, a novel histamine H2‐receptor antagonist, on monochloramine‐induced gastric lesions in rats: Role of capsaicin‐sensitive sensory neurons

Journal of Gastroenterology and Hepatology ◽

10.1046/j.1440-1746.1999.01976.x ◽

1999 ◽

Vol 14 (9) ◽

pp. 859-865 ◽

Cited By ~ 16

Author(s):

Masakazu Umeda ◽

Akinobu Fujita ◽

Hideyuki Nishiwaki ◽

Koji Takeuchi

Keyword(s):

Receptor Antagonist ◽

Sensory Neurons ◽

Gastric Lesions ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats through capsaicin-sensitive afferent neurons

Gastroenterology ◽

10.1016/s0016-5085(03)82268-0 ◽

2003 ◽

Vol 124 (4) ◽

pp. A449 ◽

Cited By ~ 1

Author(s):

Kenji Nagahama ◽

Shinichi Kato ◽

Masanori Yamato ◽

Koji Takeuchi

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

Reflux Esophagitis ◽

Acid Reflux ◽

Afferent Neurons ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Protective Effect of Lafutidine, a Novel Histamine H2-Receptor Antagonist, on Dextran Sulfate Sodium-Induced Colonic Inflammation Through Capsaicin-Sensitive Afferent Neurons in Rats

Digestive Diseases and Sciences ◽

10.1023/b:ddas.0000043389.96490.76 ◽

2004 ◽

Vol 49 (10) ◽

pp. 1696-1704 ◽

Cited By ~ 22

Author(s):

Mitsuaki Okayama ◽

Ryoichi Tsubouchi ◽

Shinichi Kato ◽

Koji Takeuchi

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

Dextran Sulfate ◽

Dextran Sulfate Sodium ◽

Afferent Neurons ◽

H2 Receptor Antagonist ◽

Colonic Inflammation ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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S1626 Effect of Lafutidine, a Histamine H2-Receptor Antagonist, On Delayed Healing of Gastric Lesions Induced By 5-Fluorouracil in Rats

Gastroenterology ◽

10.1016/s0016-5085(08)61097-5 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-237

Author(s):

Yukiko Murashima ◽

Tohru Kotani ◽

Kikuko Amagase ◽

Shinichi Kato ◽

Koji Takeuchi

Keyword(s):

Receptor Antagonist ◽

Gastric Lesions ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Delayed Healing ◽

Histamine H2 Receptor Antagonist

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The novel histamine H2 receptor antagonist FRG-8813 prevents delay of wound repair induced by hydrogen peroxide in a rabbit gastric epithelial cell system

Journal of Gastroenterology and Hepatology ◽

10.1046/j.1440-1746.1998.01735.x ◽

1998 ◽

Vol 13 (11-s4) ◽

pp. S209-S213

Author(s):

NOBUHIRO SATO ◽

SUMIO WATANABE ◽

XIAN-EN WANG ◽

TARO OSADA ◽

HIROSHI TANAKA ◽

...

Keyword(s):

Hydrogen Peroxide ◽

Epithelial Cell ◽

Receptor Antagonist ◽

Wound Repair ◽

Cell System ◽

The Novel ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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ChemInform Abstract: THE STRUCTURE OF CIMETIDINE (N′-CYANO-N-METHYL-N′-(2-((5-METHYL-1H-IMIDAZOL-4-YL)METHYLTHIO)ETHYL)GUANIDINE), A HISTAMINE H2-RECEPTOR ANTAGONIST

Chemischer Informationsdienst ◽

10.1002/chin.197845071 ◽

1978 ◽

Vol 9 (45) ◽

Author(s):

E. HAEDICKE ◽

F. FRICKEL ◽

A. FRANKE

Keyword(s):

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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The metabolism in animals and man of oxmetidine—A new histamine H2-receptor antagonist

Xenobiotica ◽

10.3109/00498258409151439 ◽

1984 ◽

Vol 14 (7) ◽

pp. 509-514 ◽

Cited By ~ 1

Author(s):

P. J. Cox ◽

W. M. H. Heijbroek ◽

D. C. Taylor ◽

P. J. Wood ◽

P. R. Cresswell ◽

...

Keyword(s):

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Intragastric and intraoesophagel pH monitoring in duodenal ulcer patients: effect of the new histamine H2-receptor antagonist ramixotidine

European Journal of Clinical Pharmacology ◽

10.1007/bf00558510 ◽

1989 ◽

Vol 37 (4) ◽

pp. 405-407

Author(s):

M. Molgora ◽

G. Basilisco ◽

A. Bozzani ◽

G. Camboni ◽

P. A. Bianchi

Keyword(s):

Duodenal Ulcer ◽

Receptor Antagonist ◽

Ph Monitoring ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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