Quality of life following prophylactic gynecological surgery: experiences of female Lynch mutation carriers

2017 ◽  
Vol 17 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Holly Etchegary ◽  
Elizabeth Dicks ◽  
Laura Tamutis ◽  
Lesa Dawson
Keyword(s):  
Quality Of Life ◽  
Gynecological Surgery ◽  
Mutation Carriers

scholarly journals Assessing quality of life using the brief cancer-related worry inventory for gynecological surgery

2019 ◽  
Vol 8 (1) ◽  
pp. 1-7
Author(s):  
Ami Kikuchi ◽  
Ryo Koide ◽  
Masahiro Iwasaki ◽  
Mizue Teramoto ◽  
Seiro Satohisa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gynecological Surgery

scholarly journals Psychological well-being, marital adjustment and quality of life after hysterectomy: a comparative study

2018 ◽  
Vol 7 (12) ◽  
pp. 4960
Author(s):  
Kusum Lata Mathur ◽  
Manu Sharma ◽  
Mohua Mazumdar ◽  
Shikha Talati ◽  
Siddharth Srivastav
Keyword(s):  
Quality Of Life ◽  
Marital Adjustment ◽  
Comparison Group ◽  
Psychiatric Morbidity ◽  
Depression Scale ◽  
Well Being ◽  
Study Groups ◽  
Life Questionnaire ◽  
Gynecological Surgery

Background: Hysterectomy is the most common major gynecological surgery often performed for benign lesions. Many studies have reported adverse psychosocial outcomes post-hysterectomy. There is a paucity of studies from India addressing psychiatric morbidity after hysterectomy. To evaluate psychological wellbeing, marital adjustment and quality of life in patients undergoing hysterectomy for non-malignant conditions, in comparison with patients undergoing surgery other than hysterectomy.Methods: A cross-sectional study was conducted on 100 consecutive out-patients who underwent hysterectomy for non-malignant indications at least 6 months ago. The comparison group comprised of 50 consecutive out-patients who underwent gynecological surgery other than hysterectomy at least 6 months ago formed the comparison group. The study participants were evaluated on Hospital Anxiety and Depression Scale (HADS), Psychological General Well-being Index (PGWBI), Marital Adjustment Test (MAT) and Women’s Quality of Life Questionnaire (WOMQOL).Results: The indications for hysterectomy were: uterine leiomyoma (69%), uterovaginal prolapse (18%), dysfunctional uterine bleeding (12%), and endometriosis (1%). Abdominal hysterectomy was performed in 92 patients while 8 patients underwent vaginal hysterectomy. There were no significant differences in the study groups on scores of HADS, PGWBI, MAT and WOMQOL (p>0.05). Both the study groups had good marital adjustment and majority reported no depression and anxiety.Conclusions: There is no major psychiatric morbidity, decline in marital adjustment and quality of life after hysterectomy for benign conditions among Indian women. Future research on the ethno-cultural implications and effect of hysterectomy on mental health will be a significant addition to the available evidence in India.

scholarly journals Factors Influencing Postoperative Recovery and Time Off Work of Patients with Benign Indications for Surgery – Results of a Prospective Study

2020 ◽  
Vol 80 (07) ◽  
pp. 723-732
Author(s):  
Sophie Strozyk ◽  
Klaus-Dieter Wernecke ◽  
Jalid Sehouli ◽  
Matthias David
Keyword(s):  
Quality Of Life ◽  
Postoperative Recovery ◽  
Physical Factors ◽  
Gynecological Surgery ◽  
Health Related Quality ◽  
Recovery Index ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Abstract Objectives The study aimed to answer a number of questions: Which medical, psychological and sociodemographic factors affect the recovery of women after gynecological surgery for benign indications? Does patientsʼ health-related quality of life improve after surgical intervention? How long are patients signed off work postoperatively? How do patients assess their own capacity to work? Method Study population: All women between the ages of 18 and 67 years who underwent gynecological surgery for benign indications at the Charité Campus Virchow Clinic over a 7-month period were consecutively enrolled in the study. Four standardized patient surveys (the first survey [T0] was carried out in hospital, T1 at 1 week, T2 at 6 weeks and T3 at 7 – 8 months after discharge by telephone interview) were carried out using evaluated questionnaires to record patientsʼ recovery (Recovery Index), quality of life (RAND-36), satisfaction, complications, sociodemographic information and time off work with a medical sick note. Relevant medical and demographic data were also collected. Statistical analysis was carried out using univariate statistical tests for descriptive analysis and complex multifactorial statistical procedures to record observations over time. Results A total of 182 patients were included in this study (participation rate: 70%). Relevant prior operations (p = 0.01), in-hospital (p = 0.004) and postoperative complications (p < 0.001), preoperative psychological wellbeing (p = 0.01), physical functioning (p = 0.005) and postoperative anxiety (p = 0,006) had a significant impact on recovery (Recovery Index) and changed significantly over time (p < 0.001). The invasiveness of the surgery or sociodemographic parameters (including migration background) had no significant effect. Health-related quality of life (measured with the RAND-36 questionnaire) also improved postoperatively. More invasive surgical interventions were associated with longer sick leave times and, to a certain extent, with a poorer evaluation of patientsʼ capacity to work. Conclusion Recovery after gynecological surgery is a multifactorial process. This survey of a patient population identified psychological and physical factors which influence recovery but did not find significant sociodemographic parameters affecting recovery. Irrespective of these findings, gynecological surgery for benign indications resulted in an improvement in health-related quality of life. Prospective studies need to investigate whether psychological interventions could reduce preoperative fear and thereby improve postoperative recovery.

Quality of life in BRCA1 and BRCA2 mutation carriers (B1/2) following risk-reducing salpingo-oophorectomy (RRSO).

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 1508-1508 ◽  
Author(s):  
Susan M. Domchek ◽  
Jiaqi Li ◽  
Laura Digiovanni ◽  
Chan Voong ◽  
Rebecca Mueller ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brca2 Mutation ◽  
Brca1 And Brca2 ◽  
Mutation Carriers ◽  
Risk Reducing

Disturbances in quality of life among BRCA mutation carriers.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e12522-e12522
Author(s):  
Aileen Caceres ◽  
Rebecca McLamara ◽  
Olga Ivanov ◽  
Cynthia Buffington
Keyword(s):  
Quality Of Life ◽  
Brca Mutation ◽  
Mutation Carriers ◽  
Brca Mutation Carriers

scholarly journals Long-term satisfaction and quality of life following risk reducing surgery in BRCA1/2 mutation carriers

2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Gillian W Hooker ◽  
Lesley King ◽  
Lauren VanHusen ◽  
Kristi Graves ◽  
Beth N Peshkin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mutation Carriers ◽  
Risk Reducing

scholarly journals Online Tool to Guide Decisions for BRCA1/2 Mutation Carriers

2012 ◽  
Vol 30 (5) ◽  
pp. 497-506 ◽  
Author(s):  
Allison W. Kurian ◽  
Diego F. Munoz ◽  
Peter Rust ◽  
Elizabeth A. Schackmann ◽  
Michael Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Incidence ◽  
Prophylactic Mastectomy ◽  
Brca2 Mutation ◽  
Monte Carlo Model ◽  
Effective Prevention ◽  
Online Tool ◽  
Mutation Carriers ◽  
Risk Reducing

Purpose Women with BRCA1 or BRCA2 (BRCA1/2) mutations must choose between prophylactic surgeries and screening to manage their high risks of breast and ovarian cancer, comparing options in terms of cancer incidence, survival, and quality of life. A clinical decision tool could guide these complex choices. Methods We built a Monte Carlo model for BRCA1/2 mutation carriers, simulating breast screening with annual mammography plus magnetic resonance imaging (MRI) from ages 25 to 69 years and prophylactic mastectomy (PM) and/or prophylactic oophorectomy (PO) at various ages. Modeled outcomes were cancer incidence, tumor features that shape treatment recommendations, overall survival, and cause-specific mortality. We adapted the model into an online tool to support shared decision making. Results We compared strategies on cancer incidence and survival to age 70 years; for example, PO plus PM at age 25 years optimizes both outcomes (incidence, 4% to 11%; survival, 80% to 83%), whereas PO at age 40 years plus MRI screening offers less effective prevention, yet similar survival (incidence, 36% to 57%; survival, 74% to 80%). To characterize patients' treatment and survivorship experiences, we reported the tumor features and treatments associated with risk-reducing interventions; for example, in most BRCA2 mutation carriers (81%), MRI screening diagnoses stage I, hormone receptor-positive breast cancers, which may not require chemotherapy. Conclusion Cancer risk-reducing options for BRCA1/2 mutation carriers vary in their impact on cancer incidence, recommended treatments, quality of life, and survival. To guide decisions informed by multiple health outcomes, we provide an online tool for joint use by patients with their physicians ( http://brcatool.stanford.edu ).

Improving Surveillance and Quality of Life of BRCA Mutation Carriers

2010 ◽  
Vol 28 (22) ◽  
pp. e376-e377
Author(s):  
Niklas Loman ◽  
Åke Borg
Keyword(s):  
Quality Of Life ◽  
Brca Mutation ◽  
Mutation Carriers ◽  
Brca Mutation Carriers

Impact of risk reducing salpingo-oophorectomy on quality of life in BRCA mutation carriers. A study protocol

Maturitas ◽  
2017 ◽  
Vol 100 ◽  
pp. 125
Author(s):  
Borja Otero ◽  
Laura Martínez de Bujo ◽  
Izaskun Artola ◽  
Angela Kydd
Keyword(s):  
Quality Of Life ◽  
Study Protocol ◽  
Brca Mutation ◽  
Mutation Carriers ◽  
Brca Mutation Carriers ◽  
Risk Reducing

scholarly journals Effect of risk-reducing salpingo-oophorectomy on quality of life in Korean BRCA mutation carriers

2021 ◽  
Author(s):  
Sumin Chae ◽  
Eun-Kyu Kim ◽  
Ye Rang Jang ◽  
Angela Soeun Lee ◽  
Seul Ki Kim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brca Mutation ◽  
Mutation Carriers ◽  
Brca Mutation Carriers ◽  
Risk Reducing
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