scholarly journals PCSK9 and Lp(a) levels of children born after assisted reproduction technologies

2019 ◽  
Vol 36 (6) ◽  
pp. 1091-1099 ◽  
Author(s):  
Charalambos Vlachopoulos ◽  
Ioanna Kosteria ◽  
Sophia Sakka ◽  
Alexandra Gkourogianni ◽  
Dimitrios Terentes-Printzios ◽  
...  
Keyword(s):  
Assisted Reproduction ◽  
Assisted Reproduction Technologies

scholarly journals Granulocyte Macrophage Colony Stimulating Factor Supplementation in Culture Media for Subfertile Women Undergoing Assisted Reproduction Technologies: A Systematic Review

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Charalampos Siristatidis ◽  
Paraskevi Vogiatzi ◽  
George Salamalekis ◽  
Maria Creatsa ◽  
Nikos Vrachnis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Assisted Reproduction ◽  
Live Birth ◽  
Culture Media ◽  
Colony Stimulating Factor ◽  
Gm Csf ◽  
Assisted Reproduction Technologies ◽  
Macrophage Colony Stimulating Factor ◽  
Macrophage Colony ◽  
Stimulating Factor

Granulocyte macrophage colony stimulating factor (GM-CSF) is a cytokine/growth factor produced by epithelial cells that exerts embryotrophic effects during the early stages of embryo development. We performed a systematic review, and six studies that were performed in humans undergoing assisted reproduction technologies (ART) were located. We wanted to evaluate if embryo culture media supplementation with GM-CSF could improve success rates. As the type of studies and the outcome parameters investigated were heterogeneous, we decided not to perform a meta-analysis. Most of them had a trend favoring the supplementation with GM-CSF, when outcomes were measured in terms of increased percentage of good-quality embryos reaching the blastocyst stage, improved hatching initiation and number of cells in the blastocyst, and reduction of cell death. However, no statistically significant differences were found in implantation and pregnancy rates in all apart from one large multicenter trial, which reported favorable outcomes, in terms of implantation and live birth rates. We propose properly conducted and adequately powered randomized controlled trials (RCTs) to further validate and extrapolate the current findings with the live birth rate to be the primary outcome measure.

Role of Sperm Morphology in Deciding Between Various Assisted Reproduction Technologies

2018 ◽  
Vol 4 (3) ◽  
pp. 311-313 ◽  
Author(s):  
Taylor P. Kohn ◽  
Jaden R. Kohn ◽  
Dolores J. Lamb
Keyword(s):  
Assisted Reproduction ◽  
Sperm Morphology ◽  
Assisted Reproduction Technologies

scholarly journals The success of assisted reproduction technologies in relation to composition of the total regulatory T cell (Treg) pool and different Treg subsets

2013 ◽  
Vol 28 (11) ◽  
pp. 3062-3073 ◽  
Author(s):  
V. Schlossberger ◽  
L. Schober ◽  
J. Rehnitz ◽  
M. Schaier ◽  
M. Zeier ◽  
...  
Keyword(s):  
T Cell ◽  
Assisted Reproduction ◽  
Regulatory T Cell ◽  
Assisted Reproduction Technologies
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