Radionuclide purity assessment and calibration of 90Y(177Lu) glass particles using gamma-ray spectrometry

2011 ◽  
Vol 292 (1) ◽  
pp. 429-434
Author(s):  
H. Poorbaygi ◽  
Sh. Sheibani ◽  
S. M. R. Aghamiri ◽  
M. Azizi Shamami
2012 ◽  
Vol 27 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Elio Tomarchio

The radionuclide purity of a radiopharmaceutical product is usually measured by gamma-ray spectrometry with various measurement geometries. The importance of this test is that the radionuclide impurities, if present, result in an increase in the radiation dose to the patient without contributing to diagnostic information and in some cases may also interfere with the marking molecules and affect the proper conduct of diagnostic examination. In this work, gamma-ray spectrometry is used to determine the amounts of impurities by adopting as measurement geometry the same bottle containing eluted or prepared radiopharmaceuticals. In addition to high-purity germanium semiconductor detectors, the usefulness of NaI(Tl) and LaBr3(Ce) scintillators in routine operation is also examined. For the latter detectors, an evaluation of the minimum detectable activity was carried out and compared with the activity limits established by the regulation rules. The main cases considered are related to the first elution of 99Mo-99mTc generators and samples of 18F-FDG (fluoro-deoxy-glucose) to be used for positron emission tomography diagnostics.


2016 ◽  
Vol 32 ◽  
pp. 112-113
Author(s):  
S. Calusi ◽  
P. Saletti ◽  
L. Capaccioli

1963 ◽  
Vol 03 (02) ◽  
pp. 175-182 ◽  
Author(s):  
Bo Bergman ◽  
Rune Söremark

SummaryBy means of neutron activation and gamma-ray spectrometry the concentrations in the human mandibular articular disc of the following elements have been determined: Na, Mn, Cu, Zn, Rb, Sr, Cd, W, and Au. The discs were obtained at necropsy from seven men and nine women, ranging in age from 56 to 71 years.The activation was carried out in a thermal neutron flux of about 1.7 XlO12 neutrons × cm−2 × sec.−1 for about 20 hours. A chemical group separationwas performed before the gamma-ray spectrometry. Quantitative data based on the dry weight of the cartilage samples were obtained by comparing the photo-peak area of the identified elements with those of appropriate standards.


2019 ◽  
Author(s):  
Steven Charles Myers ◽  
Ning Xu ◽  
Jung Ho Rim ◽  
Georgiana Marie Vigil

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