Atopic dermatitis: molecular, cellular, and clinical aspects

Author(s):  
Jafar Salimian ◽  
Zahra Salehi ◽  
Ali Ahmadi ◽  
Alireza Emamvirdizadeh ◽  
Seyyed Masoud Davoudi ◽  
...  
2021 ◽  
Vol 12 (1) ◽  
pp. 1-6
Author(s):  
Emmanuel Armand Kouotou

Background: Atopic dermatitis (AD) is a chronic and recurrent inflammatory dermatitis often associated with other atopic manifestations, such as asthma and allergic rhinitis. This study aimed to determine the epidemiological and clinical aspects of AD and to assess the quality of life (QoL) of patients suffering from AD in our setting. Materials and Methods: This was a cross-sectional study conducted from February through April 2017 in seven hospitals in Cameroon. The study included patients above 18 who presented themselves to a dermatology consultation, were diagnosed with AD, and gave their consent. To assess the severity of AD and evaluate the QoL of the patients, standardized scales, such as SCORAD and QoLIAD, were employed. Results: The study enrolled 46 patients between 18 and 69 years of age with a mean age of 31 ± 12 years and the prevalence of AD at 1.5%. Most of the participants were females, with a sex ratio of 0.4:1, living in urban areas (93.5%). Food (34.8%) and cosmetic products (21.7%) were found as the main risk factors in the occurrence of AD. Upon physical examination, the upper and lower limbs were found to be the most affected in 84.8% and 54.3% of cases, respectively; in addition to cutaneous xerosis (45.7%), lichenification (43.5%), and excoriations (37%). Of the 46 patients, 9 (20%) had severe AD, 32 (70%) had moderate AD, and 5 (10%) had mild AD. QoL was impaired in 43 of the 46 patients (93.5%). Conclusion: Atopic dermatitis is a pathology that impacts the QoL of adults. A QoL assessment is, therefore, an important step in the management of AD.


2003 ◽  
Vol 3 (2) ◽  
pp. 127-138 ◽  
Author(s):  
E. Galli ◽  
R. Cicconi ◽  
P. Rossi ◽  
A. Casati ◽  
E. Brunetti ◽  
...  

2019 ◽  
Vol 13 (1) ◽  
pp. 61-67
Author(s):  
Edith Sophie Bayonne-Kombo ◽  
Hébert Loubove ◽  
Yannichka Gloria Voumbo Mavoungou ◽  
Alphonse Gathsé

Background: Atopic dermatitis is a chronic inflammatory dermatosis for which racial specificities have been reported. Objective: To describe the clinical aspects of atopic dermatitis on children. Methods: Descriptive cross-sectional study in one public hospital and one private hospital in Brazzaville, Congo, for three years. Children under the age of 16, consulted for atopic dermatitis were included. Demographic and clinical data were collected. Atopic dermatitis was defined according to the criteria of the United Kingdom Working Party and its severity appreciated by SCORAD. The data was processed by EpiInfo 7® software. Results: Seventy-five children were included. They were 49 girls (65.33%) and 26 boys (34.67%), mean age 4.3 years [9 months-12 years]. Personal atopic history was found in 46.67% of cases and family atopic history in 61.33% of cases. Initial symptoms of atopic dermatitis had occurred before 2 years of age for 65 children (86.67%). The average consultation time was 33.4 months. In infancy, erythematous vesicular or oozing plaques were observed in 68.18% of cases and scaly erythematous plaques on folds in 50% of cases. In childhood, scaly erythematous plaques were observed in 84.90% of cases and lichenified eczema in 10.67% of cases. Xerosis was noted in 89.33% of all cases. Secondary infection was seen in 33.33% of cases. Twenty-five cases (33.33%) were severe. Conclusion: This study reveals a delayed diagnosis of atopic dermatitis, unusual clinical features and the importance of secondary infection. Information for families and clinicians should be considered to improve the earliness of the diagnosis.


2009 ◽  
Vol 89 (4) ◽  
pp. 379-383 ◽  
Author(s):  
D Chrostowska-Plak ◽  
J Salomon ◽  
A Reich ◽  
JC Szepietowski

2017 ◽  
Vol 8 (Suppl. 1) ◽  
pp. 25-27 ◽  
Author(s):  
Kouadio Celestin Ahogo ◽  
Yao Isidore Kouassi ◽  
Ildevert Patrice Gbery ◽  
Kouadio Richard Azagoh ◽  
Kouame Issouf Yeboua ◽  
...  

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