The Role of Actin Microfilaments in Depression of Acetylcholine-Induced Currents in Common Snail Neurons in a Cellular Analog of Habituation

2013 ◽  
Vol 43 (5) ◽  
pp. 557-564 ◽  
Author(s):  
A. S. Pivovarov ◽  
N. A. Vasil’eva ◽  
G. B. Murzina ◽  
D. A. Makhnovskii
Keyword(s):  
Common Snail ◽  
Actin Microfilaments ◽  
Snail Neurons ◽  
Induced Currents

Role of G-proteins and second messenger systems in the plasticity of a defensive reflex in the common snail

1998 ◽  
Vol 28 (2) ◽  
pp. 101-106
Author(s):  
L. N. Grinkevich ◽  
L. B. Toporkova ◽  
P. D. Lisachev ◽  
N. L. Izvarina
Keyword(s):  
G Proteins ◽  
Second Messenger ◽  
Common Snail ◽  
Second Messenger Systems ◽  
Defensive Reflex ◽  
The Common

scholarly journals Cryo-EM structures of human TMEM120A and TMEM120B

2021 ◽  
Author(s):  
Meng Ke ◽  
Yue Yu ◽  
Changjian Zhao ◽  
Shirong Lai ◽  
Qiang Su ◽  
...  
Keyword(s):  
Potential Role ◽  
Transmembrane Domain ◽  
Transmembrane Protein ◽  
Expression System ◽  
Coiled Coil ◽  
Fatty Acid Elongase ◽  
Coiled Coil Domain ◽  
Induced Currents ◽  
The Difference

TMEM120A (Transmembrane protein 120A) was recently identified as a mechanical pain sensing ion channel named as TACAN, while its homologue TMEM120B has no mechanosensing property1. Here, we report the cryo-EM structures of both human TMEM120A and TMEM120B. The two structures share the same dimeric assembly, mediated by extensive interactions through the transmembrane domain (TMD) and the N-terminal coiled coil domain (CCD). However, the nearly identical structures cannot provide clues for the difference in mechanosensing between TMEM120A and TMEM120B. Although TMEM120A could mediate conducting currents in a bilayer system, it does not mediate mechanical-induced currents in a heterologous expression system, suggesting TMEM120A is unlikely a mechanosensing channel. Instead, the TMDs of TMEM120A and TMEM120B resemble the structure of a fatty acid elongase, ELOVL7, indicating their potential role of an enzyme in lipid metabolism.

Role of Villin in the Dynamics of Actin Microfilaments

Cell Motility ◽  
2004 ◽  
pp. 235-245
Author(s):  
Rafika Athman ◽  
Sylvie Robine ◽  
Daniel Louvard
Keyword(s):  
Actin Microfilaments

Role of Actin Microfilaments in Canine Distemper Virus Replication in Vero Cells

2004 ◽  
Vol 66 (4) ◽  
pp. 409-415 ◽  
Author(s):  
Hideo KATAYAMA ◽  
Masatoshi HORI ◽  
Koichi SATO ◽  
Masahiro KAJITA ◽  
Hiroshi OZAKI ◽  
...  
Keyword(s):  
Virus Replication ◽  
Canine Distemper Virus ◽  
Vero Cells ◽  
Actin Microfilaments ◽  
Canine Distemper
Sign in / Sign up

Export Citation Format

Share Document