According to the automobile industry cluster situation at present, the paper introduces the method and train of thought of automobile industry cluster based on GIS from demand analysis, data base design, function design and so on. Also demonstration analysis in one automobile industry cluster. In construction, use client layer, web layer, business logic layer and data layer to design the system architecture. It improved the system maintenance performance, used Oracle and ArcSDE to access space data and attribute data, and mass data storage management. Research results maybe give some significance reference for design and implementation of automobile industry cluster.