Prevalence, risk factors and clinical characteristics of renal dysfunction in Chinese outpatients with growth simple renal cysts

Abstract Background Researchers have proved that simple renal cysts (SRCs) might be correlated with renal dysfunction, but it is still controversial. Thus, we conducted clinical research study with large sample size and long-term follow-up to clarify the relationship between SRCs and renal dysfunction. Methods A total of 571 SRCs patients in outpatients of nephrology department were included, we investigated the clinical characteristics of growth SRCs compared with non-growth SRCs, evaluated the incidence of renal dysfunction in SRCs and explored the risk factors of renal dysfunction in growth SRCs. Results The mean baseline age was 51.31 ± 14.37 years in the whole cohort, ranging from 19 to 79 years, and 57.6% of them were male. The median follow-up duration was 3 years, ranging from 1 to 10 years. In addition, the final maximum diameter increased 1 mm (2.74%) per year. Patients in growth SRCs group tented to have higher percentage of hypertension, hematuria, large cyst and multiple cysts compared with non-growth SRCs group. The prevalence of renal dysfunction was 15.6% after the follow-up, and the prevalence of renal dysfunction was about 10 times higher in growth SRCs group than non-growth SRCs group (23.3% vs. 2.4%). Renal dysfunction was significantly associated with age, female, total cholesterol, diastolic blood pressure, final maximum diameter and yearly change in maximum diameter in growth SRCs. Conclusions SRCs were closely related to the decline of renal function, we recommend close follow-up for growth SRCs.

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An Observational Study with Long-Term Follow-Up of Canine Cognitive Dysfunction: Clinical Characteristics, Survival, and Risk Factors

Journal of Veterinary Internal Medicine ◽

10.1111/jvim.12109 ◽

2013 ◽

Vol 27 (4) ◽

pp. 822-829 ◽

Cited By ~ 35

Author(s):

R. Fast ◽

T. Schütt ◽

N. Toft ◽

A. Møller ◽

M. Berendt

Keyword(s):

Risk Factors ◽

Observational Study ◽

Cognitive Dysfunction ◽

Clinical Characteristics ◽

Long Term Follow Up

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Obesity and Non-Obesity Obstructive Sleep Apnoea Hypertension Syndromes (OOHS & NOOHS): New Clinical Discoveries

10.21203/rs.3.rs-706703/v1 ◽

2021 ◽

Author(s):

Chunsong Hu ◽

Qinghua Wu ◽

Juxiang Li ◽

Yanqing Wu ◽

Menghong Wang ◽

...

Keyword(s):

Risk Factors ◽

Obstructive Sleep Apnoea ◽

Clinical Characteristics ◽

Sleep Apnoea ◽

Major Adverse Cardiovascular Events ◽

Related Risk ◽

Obstructive Sleep ◽

Long Term Follow Up

Abstract Obesity, obstructive sleep apnoea (OSA) and hypertension are common clinical risk factors. Their coexistence is termed Obesity and Non-Obesity OSA Hypertension Syndromes (OOHS & NOOHS) due to high linkage. This study reported the clinical characteristics of OOHS and NOOHS. A total of 163 patients, aged 23–74 years, were randomly enrolled at the outpatients department who were either obese or non-obese, suffered OSA and hypertension. Subjects with a Body Mass Index (BMI) of ≥25 (Chinese criteria), of ≥27 (criteria of this study), and of ≥30 (WHO criteria) were defined as obese or non-obese, respectively. Cases with snoring were classified as mild, moderate and severe OSA by using the Apnoea-Hypopnoea Index where mild is 5–15, moderate is 15–30, and severe is > 30. Daytime blood pressure (BP) was measured to assess any correlation. Data from those with isolated obesity, OSA, hypertension, and metabolic syndrome were compared. Long-term follow-up was carried out. 7 typical cases with OOHS and NOOHS were assessed and included general patient information, initial diagnosis, medical history, related risk factors, BMI, and BP. 163 cases with OOHS and NOOHS often have similar or different clinical characteristics. Both potentially suffer from major adverse cardiovascular events (MACEs) which are associated with increased BMI, OSA, and increased BP. Long-term follow-up showed the outcomes consistently linked to their lifestyle and adherence to treatment. Our new clinical discoveries suggest that both OOHS and NOOHS are high risk conditions in MACEs. There is an urgent need for early lifestyle interventions and related treatments.

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Obesity and Non-Obesity Obstructive Sleep Apnoea Hypertension Syndromes (OOHS & NOOHS): New Clinical Discoveries

10.21203/rs.3.rs-677950/v1 ◽

2021 ◽

Author(s):

Chunsong Hu ◽

Qinghua Wu ◽

Juxiang Li ◽

Yanqing Wu ◽

Menghong Wang ◽

...

Keyword(s):

Risk Factors ◽

Obstructive Sleep Apnoea ◽

Clinical Characteristics ◽

Sleep Apnoea ◽

Major Adverse Cardiovascular Events ◽

High Risk Factors ◽

Obstructive Sleep ◽

Long Term Follow Up

Abstract Obesity, obstructive sleep apnoea (OSA) and hypertension are common clinical risk factors. Their coexistence is termed Obesity and Non-Obesity OSA Hypertension Syndromes (OOHS & NOOHS) due to high linkage. This study reported the clinical characteristics of OOHS and NOOHS. A total of 163 patients, aged 23–74 years, were randomly enrolled at the outpatients department who were either obese or non-obese, suffered OSA and hypertension. Subjects with a Body Mass Index (BMI) of ≥25 (Chinese criteria), of ≥27 (criteria of this study), and of ≥30 (WHO criteria) were defined as obese or non-obese, respectively. Cases with snoring were classified as mild, moderate and severe OSA by using the Apnoea-Hypopnoea Index where mild is 5–15, moderate is 15–30, and severe is > 30. Daytime blood pressure (BP) was measured to assess any correlation. Data from those with isolated obesity, OSA, hypertension, and metabolic syndrome were compared. Long-term follow-up was carried out. 7 typical cases with OOHS and NOOHS were assessed and included general patient information, initial diagnosis, medical history, related risk factors, BMI, and BP. 163 cases with OOHS and NOOHS often have similar or different clinical characteristics. Both potentially suffer from Major Adverse Cardiovascular Events (MACE) which are associated with increased BMI, OSA, and increased BP. Long-term follow-up showed the outcomes consistently linked to their lifestyle and adherence to treatment. Our new clinical discoveries suggest that both OOHS and NOOHS are high risk factors in MACE. There is an urgent need for early lifestyle interventions and related treatments.

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Post-Operative Dysphagia in Anterior Cervical Discectomy and Fusion

Annals of Otology Rhinology & Laryngology ◽

10.1177/00034894211015582 ◽

2021 ◽

pp. 000348942110155

Author(s):

Leonard Haller ◽

Khush Mehul Kharidia ◽

Caitlin Bertelsen ◽

Jeffrey Wang ◽

Karla O’Dell

Keyword(s):

Risk Factors ◽

Medical Records ◽

Assessment Tool ◽

Demographic Data ◽

Anterior Cervical Discectomy ◽

Cervical Discectomy ◽

Long Term Follow Up

Objective: We sought to identify risk factors associated with long-term dysphagia, characterize changes in dysphagia over time, and evaluate the incidence of otolaryngology referrals for patients with long-term dysphagia following anterior cervical discectomy with fusion (ACDF). Methods: About 56 patients who underwent ACDF between May 2017 to February 2019 were included in the study. All patients were assessed for dysphagia using the Eating Assessment Tool (EAT-10) survey preoperatively and late postoperatively (≥1 year). Additionally, 28 patients were assessed for dysphagia early postoperatively (2 weeks—3 months). Demographic data, medical comorbidities, intraoperative details, and post-operative otolaryngology referral rates were collected from electronic medical records. Results: Of the 56 patients enrolled, 21 patients (38%) had EAT-10 scores of 3 or more at long-term follow-up. None of the demographics, comorbidities, or surgical factors assessed were associated with long-term dysphagia. Patients who reported no long-term dysphagia had a mean EAT-10 score of 6.9 early postoperatively, while patients with long-term symptoms had a mean score of 18.1 ( P = .006). Of the 21 patients who reported persistent dysphagia symptoms, 3 (14%) received dysphagia testing or otolaryngology referrals post-operatively. Conclusion: Dysphagia is a notable side effect of ACDF surgery, but there are no significant demographics, comorbidities, or surgical risk factors that predict long-term dysphagia. Early postoperative characterization of dysphagia using the EAT-10 questionnaire can help predict long-term symptoms. There is inadequate screening and otolaryngology follow-up for patients with post-ACDF dysphagia.

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Incidence and risk factors for trocar site hernia following laparoscopic cholecystectomy: A long-term follow-up study

Hernia ◽

10.1007/s10029-012-0929-y ◽

2012 ◽

Vol 16 (4) ◽

pp. 431-437 ◽

Cited By ~ 31

Author(s):

E. Erdas ◽

C. Dazzi ◽

F. Secchi ◽

S. Aresu ◽

A. Pitzalis ◽

...

Keyword(s):

Risk Factors ◽

Laparoscopic Cholecystectomy ◽

Trocar Site ◽

Follow Up Study ◽

Trocar Site Hernia ◽

Long Term Follow Up

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Long-term follow-up results of medial opening wedge high tibia osteotomy with a pre-countered non-locking steel plate

Archives of Orthopaedic and Trauma Surgery ◽

10.1007/s00402-021-03927-8 ◽

2021 ◽

Author(s):

Simo S. A. Miettinen ◽

Hannu J. A. Miettinen ◽

Jussi Jalkanen ◽

Antti Joukainen ◽

Heikki Kröger

Keyword(s):

Risk Factors ◽

Adverse Events ◽

Mechanical Axis ◽

Steel Plate ◽

Cox Regression ◽

Opening Wedge ◽

Cumulative Survival ◽

Long Term Follow Up

Abstract Introduction This retrospective study investigated the long-term follow-up results of medial opening wedge high tibial osteotomy (MOWHTO) with a pre-countered non-locking steel plate implant (Puddu plate = PP) used for medial knee osteoarthrosis (OA) treatment. Materials and methods Consecutive 70 MOWHTOs (66 patients) were performed between 01.01.2004 and 31.12.2008 with the mean follow-up time of 11.4 (SD 4.5; range 1.2–16.1) years. The Kaplan–Meier survival analysis was used to evaluate the cumulative survival of the implant in terms of age (< 50 years old and ≥ 50 years old) and gender. Adverse events were studied and Cox regression analysis was used to evaluate risk factors [age, gender, body mass index (BMI), preoperative mechanical axis, severity of OA, use of bone grafting or substitution and undercorrection of mechanical axis from varus to valgus] for revisions. Results The estimates for the cumulative survival with no need for TKA after MOWHTO were 86% at 5 years, 67% at 10 years and 58% at 16.1 years (SE 0.6, CI 95% 11.1–13.5). A total of 33/70 (47%) adverse events occurred and 38/70 (54%) knees required some revision surgery during the follow-up. Cox regression did not show any statistically significant risk factors for revision. Conclusions The PP has feasible MOWHTO results with a cumulative survival of 67% at 10 years with no need for conversion to TKA. Many adverse events occurred and revision rate due to any reason was high. Age or gender did not have statistically significant differences in terms of survival.

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Clinical characteristics and risk factors of arrhythmia during follow‐up of patients with idiopathic ventricular fibrillation

Journal of Cardiovascular Electrophysiology ◽

10.1111/jce.14696 ◽

2020 ◽

Vol 31 (10) ◽

pp. 2677-2686

Author(s):

Niels K. Stampe ◽

Camilla B. Jespersen ◽

Charlotte Glinge ◽

Henning Bundgaard ◽

Jacob Tfelt‐Hansen ◽

...

Keyword(s):

Risk Factors ◽

Ventricular Fibrillation ◽

Clinical Characteristics ◽

Idiopathic Ventricular Fibrillation

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Risk of hemorrhage from de novo cerebral aneurysms

Journal of Neurosurgery ◽

10.3171/2012.9.jns111512 ◽

2013 ◽

Vol 118 (1) ◽

pp. 58-62 ◽

Cited By ~ 22

Author(s):

William J. Kemp ◽

Daniel H. Fulkerson ◽

Troy D. Payner ◽

Thomas J. Leipzig ◽

Terry G. Horner ◽

...

Keyword(s):

Risk Factors ◽

De Novo ◽

Patient Age ◽

Patient Âgé ◽

Long Term Follow Up ◽

De Novo Aneurysm ◽

The Mean ◽

Risk Of Hemorrhage

Object A small percentage of patients will develop a completely new or de novo aneurysm after discovery of an initial aneurysm. The natural history of these lesions is unknown. The authors undertook this statistical evaluation a large cohort of patients with both ruptured and unruptured de novo aneurysms with the aim of analyzing risk factors for rupture and estimating a risk of subarachnoid hemorrhage (SAH). Methods A review of a prospectively maintained database of all aneurysm patients treated by the vascular neurosurgery service of Goodman Campbell Brain and Spine from 1976–2010 was performed. Of the 4718 patients, 611 (13%) had long-term follow-up imaging. The authors identified 27 patients (4.4%) with a total of 32 unruptured de novo aneurysms from routine surveillance imaging. They identified another 10 patients who presented with a new SAH from a de novo aneurysm after treatment of their original aneurysm. The total study group was thus 37 patients with a total of 42 de novo aneurysms. The authors then compared the 27 patients with incidentally discovered aneurysms with the 10 patients with SAH. A statistical analysis was performed, comparing the 2 groups with respect to patient and aneurysm characteristics and risk factors. Results Thirty-seven patients were identified as having true de novo aneurysms. This group had a female predominance and a high percentage of smokers. These 37 patients had a total of 42 de novo aneurysms. Ten of these 42 aneurysms hemorrhaged. De novo aneurysms in both the SAH and non-SAH group were anatomically small (< 10 mm). The estimated risk of hemorrhage over 5 years was 14.5%, higher than the expected SAH risk of small, unruptured aneurysms reported in the ISUIA (International Study of Unruptured Intracranial Aneurysms) trial. There was no statistically significant correlation between hemorrhage and any of the following risk factors: hypertension, diabetes, tobacco and alcohol use, polycystic kidney disease, or previous SAH. There was a statistically significant between-groups difference with respect to patient age, with the mean patient age being significantly older in the SAH aneurysm group than in the non-SAH group (p = 0.047). This is likely reflective of longer follow-up and discovery time, as the mean length of time between initial treatment and discovery of the de novo aneurysm was longer in the SAH group (p = 0.011). Conclusions While rare, de novo aneurysms may have a risk for SAH that is comparatively higher than the risk associated with similarly sized, small, initially discovered unruptured saccular aneurysms. The authors therefore recommend long-term follow-up for all patients with aneurysms, and they consider a more aggressive treatment strategy for de novo aneurysms than for incidentally discovered initial aneurysms.

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