Correction to: Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula “Goshajinkigan”

The solution properties and phase behavior of ammonium hexylene octyl succinate (HOS) was investigated in water and water-oil system. The critical micelle concentration (CMC) of HOS is lower than that of anionic surfactants having same carbon number in the lipophilic part. The phase diagrams of a water/ HOS system and water/ HOS/ C10EO8/ dodecane system were also constructed. Above critical micelle concentration, the surfactant forms a normal micellar solution (Wm) at a low surfactant concentration whereas a lamellar liquid crystalline phase (La) dominates over a wide region through the formation of a two-phase region (La+W) in the binary system. The lamellar phase is arranged in the form of a biocompatible vesicle which is very significant for the drug delivery system. The surfactant tends to be hydrophilic when it is mixed with C10EO8 and a middle-phase microemulsion (D) is appeared in the water-surfactant-dodecane system where both the water and oil soluble drug ingredient can be incorporated in the form of a dispersion. Hence, mixing can tune the hydrophile-lipophile properties of the surfactant. Key words: Ammonium hexylene octyl succinate, mixed surfactant, lamellar liquid crystal, middle-phase microemulsion. Dhaka Univ. J. Pharm. Sci. Vol.3(1-2) 2004 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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PROSPECT OF INTRODUCTION OF PLANTS FROM CORN CHANDLER GENUS (Filipendula Mill.), AS SOURCES OF CRUDE DRUG

Sel skokhozyaistvennaya Biologiya ◽

10.15389/agrobiology.2012.2.73eng ◽

2012 ◽

pp. 73-79

Author(s):

N.Yu. Gudkova ◽

Keyword(s):

Crude Drug

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Dottikon set to boost drug ingredient output

C&EN Global Enterprise ◽

10.1021/cen-09842-buscon12 ◽

2020 ◽

Vol 98 (42) ◽

pp. 12-13

Author(s):

Rick Mullin

Keyword(s):

Drug Ingredient

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Inhibitory Effect of Crude-Drug Extracts on the Degranulation of Mast Cells (RBL-2H3)

Nippon Shokuhin Kagaku Kogaku Kaishi ◽

10.3136/nskkk.58.330 ◽

2011 ◽

Vol 58 (7) ◽

pp. 330-334 ◽

Cited By ~ 2

Author(s):

Mariko Asano ◽

Megumi Dohi ◽

Kazunaga Yazawa ◽

Takashi Kometani ◽

Kyoko Takahashi

Keyword(s):

Mast Cells ◽

Inhibitory Effect ◽

Crude Drug

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Difference Spectrophotometric Estimation of Santonin

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/67.5.939 ◽

1984 ◽

Vol 67 (5) ◽

pp. 939-941

Author(s):

Abdel-Azim M Habib ◽

Abdalla A Omar ◽

Taha M Sarg

Keyword(s):

Difference Spectrum ◽

Crude Drug ◽

The Difference

Abstract Santonin gives a characteristic alkaline vs acidic difference spectrum. This was used for its estimation in pharmaceuticals and in the crude drug. Santonin was first extracted and purified through a specific partition procedure; then the difference absorbance was measured either at the maximum, 285 nm, or the minimum, 242 nm. The percentage of santonin can be calculated either by reference to the difference absorbance of a reference santonin sample, treated similarly, or by making use of the determined absorptivity. Measurement at the maximum is advisable, especially when the crude drug is assayed, because natural contaminants may interfere with the difference absorbance at the minimum.

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