A case of autoimmune pulmonary alveolar proteinosis appearing as a localized ground-glass opacity

2014 ◽  
Vol 32 (11) ◽  
pp. 657-660 ◽  
Author(s):  
Katsuhide Kojima ◽  
Katsuya Kato ◽  
Takuya Fukazawa ◽  
Ichiro Morita ◽  
Nagio Takigawa ◽  
...  
2018 ◽  
Vol 10 (9) ◽  
pp. E694-E698
Author(s):  
Tsutomu Shinohara ◽  
Hiroyuki Hino ◽  
Shino Imanishi ◽  
Keishi Naruse ◽  
Yuji Ohtsuki ◽  
...  

2011 ◽  
Vol 1 (1) ◽  
pp. 2 ◽  
Author(s):  
Eiki Ichihara ◽  
Nagio Takigawa ◽  
Katsuya Kato ◽  
Yasushi Tanimoto ◽  
Ichiroh Yamadori ◽  
...  

An 80-year-old man presented with heterogeneous ground glass opacity, with interlobular septal thickening in the left lower lobe. The histology of a surgical lung biopsy showed alveolar proteinosis. Computed tomography revealed that the ground glass opacity and interlobular septal thickening observed dorsally in the supine position migrated to the ventral side in the prone position. To the best of our knowledge, this is the first report of a posture-dependent migrating shadow in a patient with pulmonary alveolar proteinosis.


Chest Imaging ◽  
2019 ◽  
pp. 423-427
Author(s):  
Juliana Bueno

Ground-glass opacity (GGO) is defined at thin-section CT as abnormally increased lung density in which vascular and bronchial margins remain visible. This contrasts with consolidation in which those margins are obscured. In the setting of diffuse lung disease, GGO may be related to airspace filling, interstitial thickening or both. Pathologic processes manifesting as diffuse GGO have widely varied symptoms according to the etiology. The assessment of diffuse GGO is primarily achieved with HRCT. Helpful features in establishing a differential diagnosis include: chronicity, distribution of opacities and ancillary findings. Differential diagnosis of acute GGO includes infection, alveolar hemorrhage and pulmonary edema. Chronic GGO may be seen in hypersensitivity pneumonitis, organizing pneumonia, acute or chronic eosinophilic pneumonia, pulmonary alveolar proteinosis and desquamative interstitial pneumonia (DIP). GGO is a nonspecific HRCT pattern that should always be interpreted in light of acuity of symptoms, specific clinical presentation and laboratory results.


Author(s):  
Roqiah Abdul Kadir ◽  
Bushra Johari ◽  
Mohammad Hanafiah ◽  
Lily Zainudin

‘Crazy-paving’ refers to the superimposition of ground-glass opacity and linear pattern on computed tomography (CT) images. ‘Crazy-paving’ was initially pathognomonic for alveolar proteinosis. Lung adenocarcinoma demonstrating both solid and crazy-paving appearances on CT is a rare occurance.


2021 ◽  
Vol 5 (2) ◽  
pp. 16-18
Author(s):  
Choon Seong Ng ◽  
Boon Hau Ng

Pulmonary alveolar proteinosis is a relatively rare syndrome of pulmonary surfactant clearance dysfunction that could present like asthma. A middle-aged pregnant lady presented with asthma-like symptoms which was negative for autoimmune screening, whom thoracic imaging consistent with ground-glass opacity superimposed with septal thickening. Whole lung bronchopulmonary lavage fluid analysis showed predominantly eosiniphilic material within alveolar space. Subsequent lung biopsy revealed positive PAS stain for eosinophilic material. Its presentation in pregnancy could pose challenge to delivery. The associated maternal infection risk could compromise fetal survival.


2021 ◽  
Vol 11 (3) ◽  
pp. 191-195
Author(s):  
Fanny Fachrucha ◽  
Sita Andarini ◽  
Mia Elhidsi ◽  
Rizky Yudha Irawan ◽  
Romi Beginta ◽  
...  

Pulmonary alveolar proteinosis (PAP) is a rare disease with mostly due to autoimmune toward granulocyte-macrophage colony-stimulating factor. In some conditions, PAP followed with secondary infection. A 34-year-old woman came with progressive shortness of breath, chronic dry cough, and mild fever. The chest High-Resolution Computed Tomography showed ground-glass opacity with septal reticulation or known as the crazy-paving pattern, and a cavity on the upper lobe of the left lung. The patient underwent bronchoscopy for diagnostic and therapeutic measures and found milky appearance bronchoalveolar lavage fluid (BALF). The serum galactomannan came out positive. Fungal infection detected from the BALF culture, Aspergillus fumigatus, hence fulfilling the diagnosis of PAP with probable invasive pulmonary aspergillosis. The patient showed clinical improvement after undergoing whole lung lavage and given anti-fungal medications.


2018 ◽  
Vol 7 (1) ◽  
pp. e00385
Author(s):  
Keishi Sugino ◽  
Masahiro Ando ◽  
Kiyoshi Mori ◽  
Eiyasu Tsuboi

Sign in / Sign up

Export Citation Format

Share Document