Rapid Improvement in Diabetes After Simple Side-to-side Jejunoileal Bypass Surgery: Does It Need a Ligation or Not?

Male Sprague-Dawley rats with a jejunoileal bypass ate 32% less in the 1st h of refeeding after an overnight fast than did sham-bypass rats. Fasted recipients injected intraperitoneally with 6-7 ml of bypass plasma also ate 32% less (P less than 0.001) during the 1st h of refeeding than did recipients of sham-bypass plasma, but subsequent intake was not significantly different. Rectal temperature, hematocrit, white blood cell count, and percent polymorphonuclear leukocytes were not different between bypass and sham-bypass rats. A test for aversive conditioning suggested that the effect of bypass plasma was not due to illness or discomfort. These data suggest that intestinal bypass produces a transferable humoral factor that suppresses food intake and that the effect is not due to illness or discomfort. If the decreased food intake in humans after intestinal bypass is due to a similar mechanism, the possibility exists that this humoral appetite-suppressant factor may be clinically useful in the treatment of morbid obesity.

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Unusual fungal infections following jejunoileal bypass surgery

Archives of Internal Medicine ◽

10.1001/archinte.140.5.643 ◽

1980 ◽

Vol 140 (5) ◽

pp. 643-645 ◽

Cited By ~ 1

Author(s):

A. W. Tustin

Keyword(s):

Bypass Surgery ◽

Fungal Infections ◽

Jejunoileal Bypass

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Comparative psychiatric status of male applicants for sexual reassignment surgery, jejunoileal bypass surgery, and psychiatric outpatient treatment

The Journal of Sex Research ◽

10.1080/00224497609550949 ◽

1976 ◽

Vol 12 (4) ◽

pp. 315-320 ◽

Cited By ~ 6

Author(s):

Howard B. Roback ◽

Embry Mckee ◽

Warren Webb ◽

Christine V. Abramowitz ◽

Stephen I. Abramowitz

Keyword(s):

Outpatient Treatment ◽

Bypass Surgery ◽

Jejunoileal Bypass ◽

Psychiatric Status ◽

Psychiatric Outpatient ◽

Sexual Reassignment Surgery

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Night Blindness and Vitamin A Deficiency following Jejunoilieal Bypass Surgery

Canadian Journal of Gastroenterology ◽

10.1155/1989/546312 ◽

1989 ◽

Vol 3 (4) ◽

pp. 138-140

Author(s):

Paul C. Adams ◽

Christopher L. Canny

Keyword(s):

Vitamin A ◽

Night Blindness ◽

Bypass Surgery ◽

Vitamin A Deficiency ◽

Serum Vitamin ◽

Jejunoileal Bypass ◽

Intestinal Bypass ◽

Oral Vitamin ◽

Visual Deficits ◽

Nutritional Vitamin

A 42-year-old man who developed severe night blindness 15 years following jejunoileal bypass surgery for morbid obesity is described. Ophthamological testing, including dark adaptation, electroretinography and serum vitamin A levels, confirmed a diagnosis of vitamin A deficiency. Oral vitamin A 25,000 iu/day for two months resulted in a full recovery of visual deficits. Nutritional vitamin A deficiency is discussed in the context of intestinal bypass surgery.

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