Multiple Nutritional Deficiencies and Metabolic Complications 20 Years after Jejunoileal Bypass Surgery

1987 ◽  
Vol 11 (5) ◽  
pp. 494-498 ◽  
Author(s):  
Jane E. Bradley ◽  
Rex O. Brown ◽  
R. Wayne Luther
1982 ◽  
Vol 243 (1) ◽  
pp. R60-R64 ◽  
Author(s):  
R. L. Atkinson ◽  
E. L. Brent

Male Sprague-Dawley rats with a jejunoileal bypass ate 32% less in the 1st h of refeeding after an overnight fast than did sham-bypass rats. Fasted recipients injected intraperitoneally with 6-7 ml of bypass plasma also ate 32% less (P less than 0.001) during the 1st h of refeeding than did recipients of sham-bypass plasma, but subsequent intake was not significantly different. Rectal temperature, hematocrit, white blood cell count, and percent polymorphonuclear leukocytes were not different between bypass and sham-bypass rats. A test for aversive conditioning suggested that the effect of bypass plasma was not due to illness or discomfort. These data suggest that intestinal bypass produces a transferable humoral factor that suppresses food intake and that the effect is not due to illness or discomfort. If the decreased food intake in humans after intestinal bypass is due to a similar mechanism, the possibility exists that this humoral appetite-suppressant factor may be clinically useful in the treatment of morbid obesity.


1989 ◽  
Vol 3 (4) ◽  
pp. 138-140
Author(s):  
Paul C. Adams ◽  
Christopher L. Canny

A 42-year-old man who developed severe night blindness 15 years following jejunoileal bypass surgery for morbid obesity is described. Ophthamological testing, including dark adaptation, electroretinography and serum vitamin A levels, confirmed a diagnosis of vitamin A deficiency. Oral vitamin A 25,000 iu/day for two months resulted in a full recovery of visual deficits. Nutritional vitamin A deficiency is discussed in the context of intestinal bypass surgery.


2009 ◽  
Vol 2 ◽  
pp. CCRep.S3226 ◽  
Author(s):  
S. Richard-Devantoy ◽  
J.B. Garrέ ◽  
B. Gohier

Postoperative complications resulting from bariatric surgery can lead to severe vitamin-deficiency states. A patient who underwent bariatric bypass surgery and later developed Wernicke's encephalopathy prompted us to present her interesting case history for discussion. Although bariatric surgery is known to be a risk factor for Wernicke's encephalopathy, this diagnosis is only rarely evoked in the postoperative course. We recommend that the occurrence of digestive, psychiatric or neurological symptoms after bariatric surgery should suggest a thiamine deficiency that must be promptly assessed. Without waiting for the results, thiamine supplementation should be initiated.


Diabetes ◽  
1978 ◽  
Vol 27 (2) ◽  
pp. 78-84 ◽  
Author(s):  
R. T. Moxley ◽  
D. H. Lockwood ◽  
J. M. Amatruda ◽  
J. D. Tobin ◽  
T. Pozefsky

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