Salvage surgery for a super-responder by gefitinib therapy for advanced lung cancer

2012 ◽  
Vol 60 (12) ◽  
pp. 851-854 ◽  
Author(s):  
Kohei Hashimoto ◽  
Hirohisa Horinouchi ◽  
Takashi Ohtsuka ◽  
Mitsutomo Kohno ◽  
Yotaro Izumi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Salvage Surgery ◽  
Advanced Lung Cancer

scholarly journals P2.18-03 Salvage Surgery After Curative-Intent Chemo and/or Radiation for Locally Advanced Lung Cancer

2019 ◽  
Vol 14 (10) ◽  
pp. S903
Author(s):  
M. Yamashita ◽  
Y. Maki ◽  
T. Ueno ◽  
H. Suehisa ◽  
D. Harada ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Salvage Surgery ◽  
Locally Advanced ◽  
Advanced Lung Cancer ◽  
Curative Intent ◽  
Locally Advanced Lung Cancer

scholarly journals A case of successful salvage surgery for advanced lung cancer with tracheo-esophageal fistula during concurrent definitive chemoradiotherapy

2019 ◽  
Vol 33 (2) ◽  
pp. 187-193
Author(s):  
Isamu Watanabe ◽  
Aritoshi Hattori ◽  
Syunki Hirayama ◽  
Kazuya Takamochi ◽  
Shiaki Oh ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Salvage Surgery ◽  
Advanced Lung Cancer ◽  
Esophageal Fistula ◽  
Definitive Chemoradiotherapy

scholarly journals Efficacy and Safety of Salvage Surgery After Molecular Targeting Drug Treatment for Advanced Lung Cancer

Haigan ◽  
2019 ◽  
Vol 59 (5) ◽  
pp. 463-466
Author(s):  
Naoya Ishibashi ◽  
Toshiharu Tabata ◽  
Ryo Nonomura ◽  
Yutaka Oshima ◽  
Takanobu Sasaki ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Drug Treatment ◽  
Salvage Surgery ◽  
Advanced Lung Cancer ◽  
Molecular Targeting ◽  
Efficacy And Safety ◽  
Molecular Targeting Drug

Salvage Surgery Compared to Surgery After Induction Chemoradiation Therapy for Advanced Lung Cancer

2021 ◽  
Author(s):  
Aki K. Kobayashi ◽  
Kazuo Nakagawa ◽  
Yuko Nakayama ◽  
Yuichiro Ohe ◽  
Masaya Yotsukura ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Salvage Surgery ◽  
Chemoradiation Therapy ◽  
Advanced Lung Cancer

Salvage surgery for lung cancer with tracheo-oesophageal fistula during concurrent chemoradiotherapy

2019 ◽  
Vol 29 (4) ◽  
pp. 641-643
Author(s):  
Isamu Watanabe ◽  
Kazuya Takamochi ◽  
Shiaki Oh ◽  
Kenji Suzuki
Keyword(s):  
Lung Cancer ◽  
Concurrent Chemoradiotherapy ◽  
Salvage Surgery ◽  
Mediastinal Lymph Node ◽  
Advanced Lung Cancer ◽  
Recurrent Nerve ◽  
Recurrent Nerve Palsy ◽  
Initial Surgery ◽  
The Right ◽  
Staged Reconstruction

Abstract A 48-year-old man presenting with cough, dysphagia and chest pain was diagnosed with advanced inoperable squamous cell carcinoma located in the right S2 with mediastinal lymph node metastases invading the oesophagus (c-T4N2M0 stage IIIB). Concurrent chemoradiotherapy (66 Gy) was planned, but he developed a tracheo-oesophageal fistula during the chemoradiotherapy course (26 Gy). A right sleeve pneumonectomy with oesophagectomy, cervical oesophagostomy and enterostomy were performed. Although bilateral recurrent nerve palsy occurred, he recovered via enhanced rehabilitation and was discharged 28 days after the salvage surgery. Three months after the initial surgery, staged reconstruction surgery of the stomach was performed. Intensive rehabilitation resulted in restored swallowing ability. He is alive with recurrent disease 12 months after surgery. This is the first report of salvage surgery for advanced lung cancer with tracheo-oesophageal fistula during concurrent chemoradiotherapy.

scholarly journals Salvage surgery after definitive chemoradiotherapy through VATS for an initial unresectable locally advanced lung cancer: an alternative consolidative modality to radiotherapy?

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Hsuan-Hsuan Yu ◽  
Yi-Wei Chen ◽  
Yi-Chen Yeh ◽  
Chien-Sheng Huang ◽  
Chao-Hua Chiu
Keyword(s):  
Lung Cancer ◽  
Salvage Surgery ◽  
Lung Resection ◽  
Locally Advanced ◽  
Lower Lobe ◽  
Stage Iiib ◽  
Advanced Lung Cancer ◽  
Mediastinal Lymphadenopathy ◽  
Definitive Chemoradiotherapy ◽  
Estimated Blood Loss

Abstract Background Definitive chemoradiotherapy (dCRT) is the first choice treatment for patients with locally advanced non-small cell lung cancer (NSCLC), but up to 35% of dCRT-treated tumors may have persistent or recurrent disease. Since the last decades, multimodality therapy showing potential for cure has become the mainstream for treatment of locally advanced NSCLCs, even some that were initially inoperable. Although salvage lung resection after dCRT has been reported with acceptable survivals, experiences in this respect are still limited. Other concerns remain debatable and inconclusive, such as dosage of radiation exposure, long interval between dCRT and surgery, and surgical comorbidity. Case presentation A 73-year-old male former smoker with diagnosis of right lower lobe of lung squamous cell carcinoma (SqCC) with multiple mediastinal lymphadenopathy, cT4N2M0, stage IIIB, received salvage right lower lobe + right middle lobe bilobectomy through video-assisted thoracoscopic surgery (VATS) after dCRT and adjuvant CRT to a total of 9000 cGy dosage of radiation. The interval from the 1st and 2nd ends of radiation to the salvage surgery was 980 and 164 days, respectively. The pre-operative forced expiratory volume in the first second was 2.33 L (101% predicted) and the diffusing capacity of the lungs for carbon monoxide was 56% predicted. The operating time was 6.5 h, and the total estimated blood loss was 50 ml. The patient was discharged on the 7th postoperative day without major complications or bronchopleural fistulas. The patient was still alive 42 months after the initial diagnosis of advanced N2 lung SqCC, and kept progression-free for 7 months after salvage lung resection. Conclusions Salvage lung resection performed long after high-dose radiation therapy of dCRT is technically feasible through VATS approach in a patient with initially inoperable cT4N2M0 stage IIIB NSCLC, and can be an alternative consolidative treatment for locally advanced NSCLC.

TP53 Exon 8 Mutations are Associated with Shorter Survival in Advanced Lung Cancer Patients

2018 ◽  
Author(s):  
Yutao Liu ◽  
Fang Xu ◽  
Yubo Wang ◽  
Qingchen Wu ◽  
Buhai Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Advanced Lung Cancer ◽  
Lung Cancer Patients

scholarly journals Dramatic response to pembrolizumab with chemotherapy followed by salvage surgery in a lung cancer patient

2021 ◽  
Author(s):  
Shunichi Saito ◽  
Gouji Toyokawa ◽  
Seiya Momosaki ◽  
Yuka Kozuma ◽  
Fumihiro Shoji ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patient ◽  
Lung Cancer Patient ◽  
Salvage Surgery
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