Portal Vein Thrombosis In Cirrhosis: Interventional Treatment Options

2021 ◽  
Vol 23 (12) ◽  
Author(s):  
Christopher Molvar ◽  
Parag Amin
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Treatment Options ◽  
Interventional Treatment ◽  
Vein Thrombosis

scholarly journals Interventional Treatment of Severe Portal Vein Thrombosis after Living-Donor Liver Transplantation

2016 ◽  
Vol 83 (5) ◽  
pp. 206-210 ◽  
Author(s):  
Youichi Kawano ◽  
Satoru Murata ◽  
Nobuhiko Taniai ◽  
Masato Yoshioka ◽  
Atsushi Hirakata ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Interventional Treatment ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Vein Thrombosis

scholarly journals Interventional treatment with the Transjugular Intrahepatic Portosystemic Shunt (TIPS) procedure may offer a preferable alternative to systemic anticoagulation in patients with cirrhosis and portal vein thrombosis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Molly N Pantelic
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Controlled Trial ◽  
Anticoagulation Therapy ◽  
Clinical Decision ◽  
Interventional Treatment ◽  
Gastroesophageal Varices ◽  
Vein Thrombosis ◽  
Randomized Controlled ◽  
Intrahepatic Portosystemic Shunt

A clinical decision report appraising: Wang Z, Jiang MS, Zhang HL, et al. Is post-tips anticoagulation therapy necessary in patients with cirrhosis and portal vein thrombosis? A randomized controlled trial. Radiology. 2016;279(3):943-951. https://doi.org/10.1148/radiol.2015150369 for a patient with cryptogenic cirrhosis, gastroesophageal varices, pancreatic cancer, and portal vein thrombosis.

Ultrasound Imaging and Interventional Treatment of Portal Vein Thrombosis

2013 ◽  
Vol 8 (2) ◽  
pp. 237-247 ◽  
Author(s):  
Katherine Kaproth-Joslin ◽  
Ashwani K. Sharma ◽  
Deborah J. Rubens
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Ultrasound Imaging ◽  
Interventional Treatment ◽  
Vein Thrombosis

scholarly journals A prospective, multicentre study in acute non-cirrhotic, non-malignant portal vein thrombosis: comparison of medical and interventional treatment

2020 ◽  
Vol 52 (2) ◽  
pp. 329-339 ◽  
Author(s):  
Martin Rössle ◽  
Dominik Bettinger ◽  
Jonel Trebicka ◽  
Christoph Klinger ◽  
Michael Praktiknjo ◽  
...  
Keyword(s):  
Portal Vein ◽  
Multicentre Study ◽  
Portal Vein Thrombosis ◽  
Interventional Treatment ◽  
Vein Thrombosis ◽  
Prospective Multicentre Study

Interventional treatment should be incorporated in the algorithm for the management of patients with portal vein thrombosis

Hepatology ◽  
2008 ◽  
Vol 48 (4) ◽  
pp. 1352-1353 ◽  
Author(s):  
Marco Senzolo ◽  
David Patch ◽  
Diego Miotto ◽  
Cecilia Ferronato ◽  
Evangelos Cholongitas ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Interventional Treatment ◽  
Vein Thrombosis

scholarly journals Radioembolization for hepatocellular carcinoma with portal vein thrombosis: Impact of liver function on systemic treatment options at disease progression

2013 ◽  
Vol 58 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Khairuddin Memon ◽  
Laura Kulik ◽  
Robert J. Lewandowski ◽  
Mary F. Mulcahy ◽  
Al B. Benson ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Function ◽  
Portal Vein ◽  
Disease Progression ◽  
Portal Vein Thrombosis ◽  
Systemic Treatment ◽  
Treatment Options ◽  
Vein Thrombosis

scholarly journals Interventional Treatment of Acute Portal Vein Thrombosis

2018 ◽  
Vol 190 (08) ◽  
pp. 740-746 ◽  
Author(s):  
Karsten Wolter ◽  
Georges Decker ◽  
Daniel Kuetting ◽  
Jonel Trebicka ◽  
Steffen Manekeller ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Interventional Procedures ◽  
Interventional Procedure ◽  
Rapid Onset ◽  
Interventional Treatment ◽  
Vein Thrombosis ◽  
Catheter Technique ◽  
Local Lysis

Background Acute portal vein thrombosis is a potentially fatal condition. In symptomatic patients not responding to systemic anticoagulation, interventional procedures have emerged as an alternative to surgery. This study sought to retrospectively evaluate initial results of interventional treatment of acute portal vein thrombosis (aPVT) using a transjugular interventional approach. Materials and Methods Between 2014 and 2016, 11 patients were treated because of aPVT (male: 7; female: 4; mean age: 41.06 years). All patients presented a rapid onset of symptoms without collateralization of portal flow as assessed by a CT scan at the time of admittance. The patients showed thrombotic occlusion of the main portal vein (11/11), the lienal vein (10/11) and the superior mesenteric vein (10/11). Different techniques for recanalization were employed: catheter thromboaspiration (1/9), AngioJet device (7/9), local-lysis-only (1/9) and TIPSS (7/9). Local lysis was administered using a dual (4/9) or single (5/9) catheter technique. The mean follow-up was 24.32 months. Results In 9 patients transhepatic access was successful. Initially reduction of thrombus load and recanalization were achieved in all 9 cases with residual thrombi in PV (n = 3), SMV (n = 7), and IL (n = 5). In the collective undergoing interventional procedures (n = 9) rethrombosis and continuous abdominal pain were seen in one patient, and thrombus progression after successful recanalization was seen in another. Freedom from symptoms could be achieved in 6 patients. One patient developed peritoneal and pleural effusion, respiratory insufficiency and portosystemic collaterals. Both patients who could not undergo an interventional procedure developed a cavernous transformation of the portal vein. One of them also had continuous intermittent abdominal pain. Conclusion Interventional percutaneous approaches are able to improve patient outcome in patients with aPVT. It appears to be of utmost importance to not only remove/reduce the thrombotic material but to establish sufficient inflow and outflow by TIPS and simultaneous multi-catheter thrombolysis. Key Points:  Citation Format

scholarly journals Portal vein thrombosis: an overview of current treatment options

2021 ◽  
Vol 84 (2) ◽  
pp. 327-332
Author(s):  
A Galante ◽  
A De Gottardi
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Current Knowledge ◽  
Treatment Options ◽  
Critical Role ◽  
Specific Treatment ◽  
Current Treatment ◽  
Thrombotic Occlusion ◽  
Vein Thrombosis ◽  
Clinical Consequences

Portal vein thrombosis (PVT) is a splanchnic vascular disorder characterised by a recent or chronic thrombotic occlusion of the portal venous system. Its aetiology is miscellaneous, and its management is demanding since PVT can play a critical role as far as morbidity and mortality are concerned. Indeed, PVT can develop as a complication of portal hypertension (PH), in association or not with advanced chronic liver disease, and aggravate its clinical consequences such as variceal bleeding and ascites. Furthermore, a diagnosis of PVT in a non-cirrhotic context can potentially reveal a previously unknown hypercoagulable condition, requiring further diagnostic steps and specific treatment in addition to anticoagulation. In addition to established therapeutic approaches, new strategies, including newer pharmacological treatments and interdisciplinary invasive procedures, gain more attention and have been increasingly introduced into clinical practice. This review aims at discussing the current knowledge in terms of treatment options for PVT.

Management of Portal and Mesenteric Venous Thrombosis

2020 ◽  
Vol 04 (02) ◽  
pp. 122-133
Author(s):  
Joshua A. Turkeltaub ◽  
Michael Kriss
Keyword(s):  
Risk Factors ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Mesenteric Ischemia ◽  
Treatment Options ◽  
Rare Condition ◽  
Mesenteric Venous Thrombosis ◽  
Vein Thrombosis ◽  
Clinical Considerations ◽  
Transplant Candidates

AbstractPortal vein thrombosis is a rare condition seen in the general population, though is more prevalent in certain populations with thrombophilia as well as in patients with cirrhosis. Because morbidity and mortality can be significant with portal vein thrombosis, diagnosis and appropriate management are crucial. In noncirrhotic patients, untreated portal vein thrombosis can result in mesenteric ischemia and complications of portal hypertension. In cirrhosis, portal vein thrombosis is often incidentally found on routine screening imaging, and the treatment outside of transplant candidates is more controversial. In this review, we will outline risk factors for portal vein thrombosis, discuss indications for treatment, and evaluate both pharmacological and endovascular treatment options, highlighting unique clinical considerations dependent on the presence or absence of cirrhosis.

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