An oral calcitonin gene-related peptide receptor antagonist for acute migraine management: Sign of a possible new chapter in headache medicine

2009 ◽  
Vol 9 (2) ◽  
pp. 91-93
Author(s):  
Ivan Garza
Keyword(s):  
Receptor Antagonist ◽  
Calcitonin Gene Related Peptide ◽  
Acute Migraine ◽  
Peptide Receptor ◽  
Related Peptide ◽  
Calcitonin Gene

scholarly journals Calcitonin gene-related peptide receptor antagonist ubrogepant for the treatment of acute migraine

Medicine ◽  
2021 ◽  
Vol 100 (8) ◽  
pp. e24741
Author(s):  
Zizhen Zhang ◽  
Yunfeng Shu ◽  
Yun Diao ◽  
Yang Du ◽  
Lizhi Chen ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Calcitonin Gene Related Peptide ◽  
Acute Migraine ◽  
Peptide Receptor ◽  
Related Peptide ◽  
Calcitonin Gene

scholarly journals A Short on Ubrogepant

2021 ◽  
pp. 79-81
Author(s):  
S. Padmaja ◽  
J. Mohan
Keyword(s):  
Receptor Antagonist ◽  
Research Process ◽  
Calcitonin Gene Related Peptide ◽  
Review Article ◽  
Acute Migraine ◽  
Cgrp Receptor ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Acute Attacks ◽  
Cgrp Receptor Antagonist

Migraine is a mysterious disorder characterized by pulsating head ache, which is actually characterized to one side and comes in attacks which will be lasting for about 3-48 hours and can be associated with nausea,vomiting,sensitivity to sound,flashes of light,vertigoand diarrhoea [1]. Most of the drugs which are in current use for actue migraine like triptans, treats the disorder symptomatically. A novel group of drugs has been in research for the migraine which treats the disorder pathologically. Calcitonin gene – related peptide (CGRP) has a major role in the pathophysiology of the disorder and hence CGRP receptor antagonist, known as Gepants are in the research process [2]. Gepants are being studied for the efficacy of treating acute migraine [2]. This article will be a review article about the drug – Ubrogepant, which is approved for treatment of migraine with acute attacks in adults [3].

Pharmacological Properties of MK-3207, a Potent and Orally Active Calcitonin Gene-Related Peptide Receptor Antagonist

2010 ◽  
Vol 333 (1) ◽  
pp. 152-160 ◽  
Author(s):  
Christopher A. Salvatore ◽  
Eric L. Moore ◽  
Amy Calamari ◽  
Jacquelynn J. Cook ◽  
Maria S. Michener ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Calcitonin Gene Related Peptide ◽  
Pharmacological Properties ◽  
Peptide Receptor ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Orally Active
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