Update on HIV Dementia and HIV-Associated Neurocognitive Disorders

2014 ◽  
Vol 14 (8) ◽  
Author(s):  
Bruce J. Brew ◽  
Phillip Chan
Keyword(s):  
Neurocognitive Disorders ◽  
Hiv Dementia ◽  
Hiv Associated Neurocognitive Disorders

scholarly journals International HIV Dementia Scale for HIV-Associated Neurocognitive Disorders: A Systematic Review and Meta-Analysis

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1124
Author(s):  
Elena Cecilia Rosca ◽  
Philippe Tadger ◽  
Amalia Cornea ◽  
Raluca Tudor ◽  
Cristian Oancea ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Quality Assessment ◽  
Meta Analysis ◽  
Neurocognitive Disorders ◽  
Small Samples ◽  
People Living With Hiv ◽  
Hiv Dementia ◽  
Cross Sectional ◽  
Hiv Associated Neurocognitive Disorders ◽  
International Hiv Dementia Scale

The present study aims to systematically review the evidence on the accuracy of the International HIV Dementia Scale (IHDS) test for diagnosing human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) and outline the quality and quantity of research evidence available on the accuracy of IHDS in people living with HIV. We conducted a systematic literature review, searching five databases from inception until July 2020. We extracted dichotomized positive and negative test results at various thresholds and calculated the sensitivity and specificity of IHDS. Quality assessment was performed according to the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) criteria. Fifteen cross-sectional studies, published between 2011 and 2018, met the inclusion criteria for meta-analysis. Overall, 3760 patients were included, but most studies recruited small samples. We assessed most studies as being applicable to the review question, though we had concerns about the selection of participants in three studies. The accuracy of IHDS was investigated at thirteen cut-off points (scores 6–12). The threshold of 10 is the most useful for optimal HAND screening (including asymptomatic neurocognitive disorder, symptomatic HAND, and HIV-associated dementia) with fair diagnostic accuracy.

scholarly journals Concurrent Classification Accuracy of the HIV Dementia Scale for HIV-Associated Neurocognitive Disorders in the CHARTER Cohort

2013 ◽  
Vol 62 (1) ◽  
pp. 36-42 ◽  
Author(s):  
Maiko Sakamoto ◽  
Thomas D. Marcotte ◽  
Anya Umlauf ◽  
Donald Franklin ◽  
Robert K. Heaton ◽  
...  
Keyword(s):  
Classification Accuracy ◽  
Neurocognitive Disorders ◽  
Hiv Dementia ◽  
Hiv Associated Neurocognitive Disorders

Youth perinatal HIV-associated neurocognitive disorders: association with functional impairment

AIDS Care ◽  
2021 ◽  
pp. 1-5
Author(s):  
Nicole Phillips ◽  
Kevin G. F. Thomas ◽  
Bulelwa Mtukushe ◽  
Landon Myer ◽  
Heather J. Zar ◽  
...  
Keyword(s):  
Functional Impairment ◽  
Neurocognitive Disorders ◽  
Perinatal Hiv ◽  
Hiv Associated Neurocognitive Disorders

scholarly journals The Role of Host Genetics in the Susceptibility for HIV-associated Neurocognitive Disorders

2008 ◽  
Vol 13 (1) ◽  
pp. 118-132 ◽  
Author(s):  
Andrew J. Levine ◽  
Elyse J. Singer ◽  
Paul Shapshak
Keyword(s):  
Neurocognitive Disorders ◽  
Host Genetics ◽  
Hiv Associated Neurocognitive Disorders
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