An Overview of Mesenchymal Stem Cell-based Therapy Mediated by Noncoding RNAs in the Treatment of Neurodegenerative Diseases

Author(s):  
Yifen Luo ◽  
Wei Qiu ◽  
Buling Wu ◽  
Fuchun Fang
2015 ◽  
Vol 23 (4) ◽  
pp. 465-482 ◽  
Author(s):  
Meirong Li ◽  
Yali Zhao ◽  
Haojie Hao ◽  
Weidong Han ◽  
Xiaobing Fu

2012 ◽  
Vol 10 (1) ◽  
pp. 77-89 ◽  
Author(s):  
Vaibhav Mundra ◽  
Ivan C. Gerling ◽  
Ram I. Mahato

2018 ◽  
Vol 105 (5) ◽  
pp. 1523-1530 ◽  
Author(s):  
Shinya Takahashi ◽  
Kei Nakagawa ◽  
Mayumi Tomiyasu ◽  
Ayumu Nakashima ◽  
Keijiro Katayama ◽  
...  

2020 ◽  
Vol Volume 14 ◽  
pp. 3995-4001 ◽  
Author(s):  
Chenghai Li ◽  
Hua Zhao ◽  
Bin Wang

2017 ◽  
Vol 14 (2) ◽  
pp. 153-165 ◽  
Author(s):  
Bojana Simovic Markovic ◽  
Tatjana Kanjevac ◽  
C. Randall Harrell ◽  
Marina Gazdic ◽  
Crissy Fellabaum ◽  
...  

Cells ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 2663
Author(s):  
Rodrigo Pinheiro Araldi ◽  
Fernanda D’Amelio ◽  
Hugo Vigerelli ◽  
Thatiana Correa de Melo ◽  
Irina Kerkis

The aging population has contributed to the rapid rise in the global incidence of neurodegenerative diseases. Despite the medical advances, there are no effective treatments for these disorders. Therefore, there is an urgent need for new treatments for these diseases. In this sense, cell therapy has been recognized as the best candidate for treating incurable diseases, such as neurodegenerative disorders. However, the therapeutic use of these cells can be limited by several factors. Thus, there has been a rediscovery that extracellular vesicles, including exosomes, can be alternatively explored in the treatment of these diseases, overcoming the limits of cell-based therapy. In this sense, this review aims to revisit all areas from biology, including biogenesis and the content of exosomes, to biotechnology, proposing the minimal information required to isolate, characterize, and study the content of these vesicles for scientific and/or clinical purposes.


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