Role of PTHrP in Mammary Gland Development and Breast Cancer

2014 ◽  
Vol 12 (3) ◽  
pp. 178-189 ◽  
Author(s):  
Minoti Hiremath ◽  
John Wysolmerski
Keyword(s):  
Breast Cancer ◽  
Mammary Gland ◽  
Mammary Gland Development ◽  
Gland Development

Lifelong exposure to n-3 PUFA affects pubertal mammary gland development

2014 ◽  
Vol 39 (6) ◽  
pp. 699-706 ◽  
Author(s):  
Breanne M. Anderson ◽  
Mira B. MacLennan ◽  
Lyn M. Hillyer ◽  
David W.L. Ma
Keyword(s):  
Breast Cancer ◽  
Mammary Gland ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Dietary Fat ◽  
Mammary Gland Development ◽  
Morphological Development ◽  
Terminal End Buds ◽  
Gland Development

There is growing evidence that early developmental periods may importantly influence future breast cancer risk. Also, there is great interest in the role of dietary fat in breast cancer risk, but the role of dietary fat during pubertal mammary gland development remains poorly understood. This study investigated the effect of n-3 polyunsaturated fatty acids (PUFA) using complementary dietary and genetic approaches to examine the effect of lifelong exposure of n-3 PUFA or n-6 PUFA (control) on mammary gland development and fatty acid composition. n-3 PUFA from both diet and genetics were enriched in mammary glands as early as 3 weeks of age. Parameters related to mammary gland development, including number of terminal end buds (TEB), percent coverage of ductal tree, and infiltration of TEB, were influenced by n-3 PUFA at 3 and 4 weeks of age. Overall, findings suggest that n-3 PUFA incorporation into the mammary gland early in life plays a role in the morphological development of the mammary gland during puberty.

scholarly journals Role of JNK in Mammary Gland Development and Breast Cancer

2011 ◽  
Vol 72 (2) ◽  
pp. 472-481 ◽  
Author(s):  
Cristina Cellurale ◽  
Nomeda Girnius ◽  
Feng Jiang ◽  
Julie Cavanagh-Kyros ◽  
Shaolei Lu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mammary Gland ◽  
Mammary Gland Development ◽  
Gland Development

scholarly journals Abstract 5114: The role of amphiregulin in mammary gland development and breast cancer

2018 ◽  
Author(s):  
Serena Mao ◽  
Minji Park ◽  
Ramon Cabrera ◽  
John Christin ◽  
George Karagiannis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mammary Gland ◽  
Mammary Gland Development ◽  
Gland Development

The Role of Smoothened in Mammary Gland Development and Breast Cancer.

2009 ◽  
Author(s):  
A. Visbal ◽  
A. Visbal ◽  
H. Villanueva ◽  
H. Villanueva ◽  
J. Rosen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mammary Gland ◽  
Mammary Gland Development ◽  
Gland Development
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