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Glyceraldehyde-3-Phosphate Dehydrogenase Facilitates Macroautophagic Degradation of Mutant Huntingtin Protein Aggregates
Molecular Neurobiology
◽
10.1007/s12035-021-02532-5
◽
2021
◽
Author(s):
Surbhi Chaudhary
◽
Asmita Dhiman
◽
Rahul Dilawari
◽
Gaurav Kumar Chaubey
◽
Sharmila Talukdar
◽
...
Keyword(s):
Protein Aggregates
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
Download Full-text
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Cited By
References
Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in Caenorhabditis elegans model of Huntington’s disease
Drug Design Development and Therapy
◽
10.2147/dddt.s94666
◽
2016
◽
pp. 1443
◽
Cited By ~ 5
Author(s):
Yixuan Zeng
◽
Wenyuan Guo
◽
Guangqing Xu
◽
Luyang Feng
◽
Simei Long
◽
...
Keyword(s):
Caenorhabditis Elegans
◽
Protective Effect
◽
Small Molecules
◽
Protein Aggregates
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
Download Full-text
Accelerating the clearance of mutant huntingtin protein aggregates through autophagy induction by europium hydroxide nanorods
Biomaterials
◽
10.1016/j.biomaterials.2013.10.024
◽
2014
◽
Vol 35
(3)
◽
pp. 899-907
◽
Cited By ~ 46
Author(s):
Peng-Fei Wei
◽
Li Zhang
◽
Susheel Kumar Nethi
◽
Ayan Kumar Barui
◽
Jun Lin
◽
...
Keyword(s):
Protein Aggregates
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Autophagy Induction
◽
Mutant Huntingtin Protein
Download Full-text
Mutant Huntingtin Protein Measurement
10.32388/copmta
◽
2020
◽
Author(s):
Keyword(s):
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
◽
Protein Measurement
Download Full-text
D01 Two independent validations of a mutant huntingtin protein (MHTT) assay to support the clinical development of mHTT-targeting therapies in HD
10.1136/jnnp-2021-ehdn.32
◽
2021
◽
Author(s):
David Hawellek
◽
Stephanie Vauleon
◽
Katharina Schutz
◽
Benoit Massonnet
◽
Nanda Gruben
◽
...
Keyword(s):
Clinical Development
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
Download Full-text
The pathobiology of perturbed mutant huntingtin protein–protein interactions in Huntington's disease
Journal of Neurochemistry
◽
10.1111/jnc.14853
◽
2019
◽
Vol 151
(4)
◽
pp. 507-519
◽
Cited By ~ 10
Author(s):
Erich E. Wanker
◽
Anne Ast
◽
Franziska Schindler
◽
Philipp Trepte
◽
Sigrid Schnoegl
Keyword(s):
Huntington's Disease
◽
Huntington’S Disease
◽
Protein Interactions
◽
Mutant Huntingtin
◽
Protein Protein Interactions
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
Download Full-text
The Aggregation-Prone Mutant Huntingtin Protein in a Cellular Context - Approaches by Super-Resolution Imaging
Biophysical Journal
◽
10.1016/j.bpj.2013.11.3780
◽
2014
◽
Vol 106
(2)
◽
pp. 683a
◽
Cited By ~ 1
Author(s):
Steffen J. Sahl
◽
Willianne I.M. Vonk
◽
Lucien E. Weiss
◽
Lana Lau
◽
Judith Frydman
◽
...
Keyword(s):
Super Resolution
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
◽
Cellular Context
◽
Resolution Imaging
Download Full-text
An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity
Cell Death and Disease
◽
10.1038/cddis.2012.121
◽
2012
◽
Vol 3
(8)
◽
pp. e382-e382
◽
Cited By ~ 46
Author(s):
G Cisbani
◽
F Cicchetti
Keyword(s):
Molecular Mechanisms
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
◽
Protein Toxicity
Download Full-text
Super-resolution fluorescence imaging of intracellular mutant huntingtin protein reveals a population of fibrillar aggregates co-existing with compact perinuclear inclusion bodies
Molecular Neurodegeneration
◽
10.1186/1750-1326-8-s1-o18
◽
2013
◽
Vol 8
(Suppl 1)
◽
pp. O18
Author(s):
Steffen J Sahl
◽
Lucien E Weiss
◽
Lana Lau
◽
Judith Frydman
◽
WE Moerner
Keyword(s):
Fluorescence Imaging
◽
Inclusion Bodies
◽
Super Resolution
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
Download Full-text
Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein
Journal of Neurochemistry
◽
10.1111/j.1471-4159.2004.02372.x
◽
2004
◽
Vol 89
(4)
◽
pp. 974-987
◽
Cited By ~ 25
Author(s):
Kazuhiko Tagawa
◽
Masataka Hoshino
◽
Tomohiro Okuda
◽
Hiroko Ueda
◽
Hiroshi Hayashi
◽
...
Keyword(s):
Cell Death
◽
Primary Neurons
◽
Mutant Huntingtin
◽
Huntingtin Protein
◽
Different Types
◽
Mutant Huntingtin Protein
Download Full-text
Effect of Pesticides on the Aggregation of Mutant Huntingtin Protein
Molecular Neurobiology
◽
10.1007/s12035-012-8252-2
◽
2012
◽
Vol 45
(3)
◽
pp. 405-414
◽
Cited By ~ 5
Author(s):
Ruhi S. Deshmukh
◽
Rajeev K. Chaudhary
◽
Ipsita Roy
Keyword(s):
Mutant Huntingtin
◽
Huntingtin Protein
◽
Mutant Huntingtin Protein
Download Full-text
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