Inflammatory Variant of Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma of the Buccal Mucosa: An Overview and Case Report with a 10-Year Follow-Up

A liposarcoma is extremely rare in the digits. A 73-year-old woman was diagnosed with a lipoma in her middle finger 10 years ago. As this tumor increased in size and presented with imaging findings that were atypical of lipomas, careful marginal resection biopsy outside the pseudo-capsule was performed, and the tumor was diagnosed as a well-differentiated liposarcoma. At the 5-year follow-up, the patient showed no evidence of local recurrence or metastasis, with no loss of hand function. The findings from this case suggest that even for a lipomatous tumor in the digits, further imaging examination and resection biopsy should be considered if the tumor presents with features that are atypical of lipomas.

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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma of the Gingiva: A Case Report and Review of Literature

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2013.06.222 ◽

2014 ◽

Vol 72 (2) ◽

pp. 431-439 ◽

Cited By ~ 12

Author(s):

Young Bin Kim ◽

Dae Ho Leem ◽

Jin A. Baek ◽

Seung O. Ko

Keyword(s):

Case Report ◽

Review Of Literature ◽

Atypical Lipomatous Tumor ◽

Lipomatous Tumor ◽

Well Differentiated

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Well-Differentiated Liposarcoma, an Atypical Lipomatous Tumor, of the Mesentery: A Case Report and Review of the Literature

Case Reports in Oncology ◽

10.1159/000327266 ◽

2011 ◽

Vol 4 (1) ◽

pp. 178-185 ◽

Cited By ~ 12

Author(s):

Takashi Yuri ◽

Takeshi Miyaso ◽

Hiroaki Kitade ◽

Kosho Takasu ◽

Nobuaki Shikata ◽

...

Keyword(s):

Case Report ◽

Review Of The Literature ◽

Atypical Lipomatous Tumor ◽

Lipomatous Tumor ◽

Well Differentiated

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A rapidly growing giant atypical lipomatous tumor / well-differentiated liposarcoma of the cheek in an elderly patient: A case report

Japanese Journal of Oral & Maxillofacial Surgery ◽

10.5794/jjoms.67.265 ◽

2021 ◽

Vol 67 (5) ◽

pp. 265-269

Author(s):

Eri FUKAYA ◽

Fumihiko MATSUSHITA ◽

Yoshiko WATANABE ◽

Yoshiyuki UCHIYAMA ◽

Kazuma MASUMOTO ◽

...

Keyword(s):

Elderly Patient ◽

Case Report ◽

Atypical Lipomatous Tumor ◽

Lipomatous Tumor ◽

Well Differentiated

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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Arising from the Tongue: case report

Kosin Medical Journal ◽

10.7180/kmj.2020.35.1.58 ◽

2020 ◽

Vol 35 (1) ◽

pp. 58-63

Author(s):

Young Chul Kim ◽

Somi Ryu ◽

Seong Jun Won ◽

Jung Je Park

Keyword(s):

Case Report ◽

Atypical Lipomatous Tumor ◽

Lipomatous Tumor ◽

Well Differentiated

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Atypical Lipomatous Tumor in Buccal Mucosa: a Case Report

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2018.02.246 ◽

2018 ◽

Vol 126 (3) ◽

pp. e83

Author(s):

Pierre González Díaz ◽

Guillermo Molina Vidal ◽

Penélope Ivonne Manzano ◽

Rogelio José Scougall Vilchis ◽

Edith Lara Carrillo ◽

...

Keyword(s):

Case Report ◽

Buccal Mucosa ◽

Atypical Lipomatous Tumor ◽

Lipomatous Tumor

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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Developed in a Patient with Progressive Muscular Dystrophy: A Case Report and Review of the Literature

Case Reports in Orthopedics ◽

10.1155/2017/3025084 ◽

2017 ◽

Vol 2017 ◽

pp. 1-4

Author(s):

Ryo Miyagi ◽

Toshihiko Nishisho ◽

Shinjiro Takata ◽

Yoshimitsu Shimatani ◽

Shunichi Toki ◽

...

Keyword(s):

Muscular Dystrophy ◽

Muscle Atrophy ◽

Fibrous Tissue ◽

Left Thigh ◽

Case Presentation ◽

Progressive Muscular Dystrophy ◽

Atypical Lipomatous Tumor ◽

Lipomatous Tumor ◽

Well Differentiated

Background. Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLS) is an intermediate or locally aggressive form of adipocytic soft tissue sarcoma. Muscular dystrophy (MD) is characterized by progressive muscle atrophy and its replacement by adipose and fibrous tissue. Recently, some authors have reported that MD genes are related to neoplastic formation, but there have been no detailed clinical reports of ALT associated with MD. Case Presentation. A 73-year-old woman with a diagnosis of limb-girdle MD visited our department for recurrence of a huge tumor in her left thigh. She had undergone resection of a lipoma at the same site more than 20 years earlier. Imaging studies revealed a lipomatous tumor in her left thigh. We performed marginal resection including the adjacent muscles. Histological diagnosis was atypical lipomatous tumor. The postoperative course was uneventful, with no recurrence at 36 months of follow-up. Conclusion. We encountered a huge atypical tumor in a patient with MD. This is the first detailed report to describe an association between ALT and MD. We hypothesize that degenerative changes occurring in adipose tissue during muscle atrophy can cause lipomatous neoplasms and moreover that the mutation of MD-related genes may lead to the proliferation of tumor cells or to malignancy.

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