Comparison of 18F-FDG PET/CT and 67Ga-SPECT for the diagnosis of fever of unknown origin: a multicenter prospective study in Japan

Author(s):  
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Noriko Tanaka ◽  
Yoko Miyata ◽  
Hiroshi Ohtsu ◽  
Tadaki Nakahara ◽  
...  
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Jan Däbritz ◽  
Michael Frosch ◽  
Markus Loeffler ◽  
Matthias Weckesser ◽  
...  

2021 ◽  
pp. 209-216
Author(s):  
Ilse J. E. Kouijzer ◽  
Chantal P. Bleeker-Rovers ◽  
Lioe-Fee de Geus-Oei

2016 ◽  
Vol 37 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Ashoka M.V. Pereira ◽  
Lars Husmann ◽  
Bert-Ram Sah ◽  
Edouard Battegay ◽  
Daniel Franzen

QJM ◽  
2014 ◽  
Vol 108 (4) ◽  
pp. 289-298 ◽  
Author(s):  
A. Gafter-Gvili ◽  
S. Raibman ◽  
A. Grossman ◽  
T. Avni ◽  
M. Paul ◽  
...  

2015 ◽  
Vol 24 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Anastas Demirev ◽  
Boudewijn Brans ◽  
Floris Vanmolkot ◽  
Rick De Graaf ◽  
Felix Mottaghy ◽  
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2021 ◽  
Vol 10 (17) ◽  
pp. 3831
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Simon Letertre ◽  
Pierre Fesler ◽  
Laetitia Zerkowski ◽  
Marie-Christine Picot ◽  
Jean Ribstein ◽  
...  

Objective: To explore the diagnostic contribution of the 18F-FDG-PET/CT in a population of patients with classical fever of unknown origin (FUO), to pinpoint its place in the diagnostic decision tree in a real-life setting, and to identify the factors associated with a diagnostic 18F-FDG-PET/CT. Method: All adult patients (aged ≥ 18 years) with a diagnosis of classical FUO who underwent an 18F-FDG-PET/CT in the University Hospital of Montpellier (France) between April 2012 and December 2017 were included. True positive 18F-FDG-PET/CT, which evidenced a specific disease causing FUO, were considered to be contributive. Results: Forty-four patients with FUO have been included (20 males, 24 females; mean age 57.5 ± 17.1 years). Diagnoses were obtained in 31 patients (70.5%), of whom 17 (38.6%) had non-infectious inflammatory diseases, 9 had infections (20.5%), and 3 had malignancies (6.8%). 18F-FDG-PET/CT was helpful for making a final diagnosis (true positive) in 43.6% of all patients. Sensitivity and specificity levels were 85% and 37%, respectively. A total of 135 investigations were performed before 18F-FDG-PET/CT, mostly CT scans (93.2%) and echocardiography (59.1%), and 108 after 18F-FDG-PET/CT, mostly biopsies (including the biopsy of a temporal artery) (25%) and MRIs (34%). In multivariate analysis, the hemoglobin level was significantly associated with a helpful 18F-FDG-PET/CT (p = 0.019, OR 0.41; 95% CI (0.20–0.87)), while the CRP level was not associated with a contributive 18F-FDG-PET/CT. Conclusion: 18F-FDG-PET/CT may be proposed as a routine initial non-invasive procedure in the diagnostic workup of FUO, especially in anemic patients who could be more likely to benefit from 18F-FDG-PET/CT.


2019 ◽  
Vol 152 (3) ◽  
pp. 125
Author(s):  
Juan Jose Martin-Marcuartu ◽  
Jose Antonio Lojo-Ramirez ◽  
Victor Manuel Pachón-Garrudo ◽  
José Manuel Jimenez-Hoyuela

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