Comparison of HPLC Separation of Phenylalanine Enantiomers on Different Types of Chiral Stationary Phases

2018 ◽  
Vol 11 (12) ◽  
pp. 3314-3323 ◽  
Author(s):  
Anna Lomenova ◽  
Katarína Hroboňová
Keyword(s):  
Stationary Phases ◽  
Chiral Stationary Phases ◽  
Hplc Separation ◽  
Different Types

Direct HPLC separation of ?-aminoester enantiomers on totally synthetic chiral stationary phases

1997 ◽  
Vol 11 (5) ◽  
pp. 317-320 ◽  
Author(s):  
F. Gasparrini ◽  
I. D'Acquarica ◽  
C. Villani ◽  
C. Cimarelli ◽  
G. Palmieri
Keyword(s):  
Stationary Phases ◽  
Chiral Stationary Phases ◽  
Hplc Separation

Direct HPLC separation of carnosine enantiomers with two chiral stationary phases based on penicillamine and teicoplanin derivatives

2018 ◽  
Vol 41 (6) ◽  
pp. 1240-1246 ◽  
Author(s):  
Laura Fumagalli ◽  
Lucia Pucciarini ◽  
Luca Regazzoni ◽  
Ettore Gilardoni ◽  
Marina Carini ◽  
...  
Keyword(s):  
Stationary Phases ◽  
Chiral Stationary Phases ◽  
Hplc Separation

scholarly journals HPLC separation of panthenol enantiomers on different types of chiral stationary phases

2018 ◽  
Vol 11 (2) ◽  
pp. 114-119 ◽  
Author(s):  
Anna Lomenova ◽  
Katarína Hroboňová ◽  
Terézia Šolónyová
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Mobile Phase ◽  
High Performance ◽  
Limit Of Detection ◽  
Stationary Phases ◽  
Pharmaceutical Preparations ◽  
Chiral Stationary Phases ◽  
Biologically Active ◽  
Different Types

Abstract Panthenol is a biologically active compound closely related to vitamin B5 (pantothenic acid). This work deals with the separation of panthenol enantiomers using high performance liquid chromatography. Different types of chiral stationary phases (β-cyclodextrin, isopropyl carbamate cyclofructan 6, amylose tris(3,5-dimethylphenylcarbamate)) were tested in normal phase separation mode. Effect of mobile phase composition on the resolution and retention of enantiomers was studied. Two types of detectors, low-wavelength UV and polarimetric, were used. The optimal chromatographic system includes a chiral stationary phase based on amylose and a mobile phase of hexane/ethanol (60/40, v/v) where the resolution of enantiomers reached the value Rs = 2.49. Suitable chromatographic conditions were applied for the determination of panthenol enantiomers in samples of pharmaceutical preparations with the obtained recovery of more than 92 %. Linearity of the high performance liquid chromatography method with spectrophotometric detection was from 1.0 × 10−3 to 1.3 mg mL−1 (R2 = 0.998), with the limit of detection of 0.3 × 10−3 mg mL−1 for both enantiomers.

HPLC separation of 2-aryloxycarboxylic acid enantiomers on chiral stationary phases

2021 ◽  
Vol 70 (5) ◽  
pp. 900-907
Author(s):  
A. A. Tumashov ◽  
S. A. Vakarov ◽  
L. Sh. Sadretdinova ◽  
E. N. Chulakov ◽  
G. L. Levit ◽  
...  
Keyword(s):  
Stationary Phases ◽  
Chiral Stationary Phases ◽  
Hplc Separation
Sign in / Sign up

Export Citation Format

Share Document