Efficacy of repeated cytology of pancreatic juice obtained by endoscopic nasopancreatic drainage tube for early diagnosis of pancreatic cancer: a case series including a case of carcinoma in situ

2015 ◽  
Vol 8 (4) ◽  
pp. 240-246 ◽  
Author(s):  
Shin Kato ◽  
Moriya Zakimi ◽  
Koki Yamada ◽  
Kenji Chinen ◽  
Tomiaki Kubota ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Early Diagnosis ◽  
Pancreatic Juice ◽  
Carcinoma In Situ ◽  
Case Series ◽  
Drainage Tube ◽  
Endoscopic Nasopancreatic Drainage ◽  
Nasopancreatic Drainage

Sa1509 Clinical Values of Cytodiagnosis Using Pancreatic Juice Multiple Times via Endoscopic Nasopancreatic Drainage for Early Diagnosis of Pancreatic Cancer

2016 ◽  
Vol 83 (5) ◽  
pp. AB278 ◽  
Author(s):  
Tomoyuki Minami ◽  
Keiji Hanada ◽  
Naomichi Hirano ◽  
Akihito Okazaki ◽  
Yoshihiro Izumi ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Early Diagnosis ◽  
Pancreatic Juice ◽  
Endoscopic Nasopancreatic Drainage ◽  
Nasopancreatic Drainage

Diagnosis of pancreatic carcinoma in situ with endoscopic nasopancreatic drainage

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S20
Author(s):  
Tomoyuki Minami ◽  
Keiji Hanada ◽  
Naomichi Hirano ◽  
Akihito Okazaki ◽  
Juri Ikemoto
Keyword(s):  
Pancreatic Carcinoma ◽  
Carcinoma In Situ ◽  
Endoscopic Nasopancreatic Drainage ◽  
Nasopancreatic Drainage

Value of Cytodiagnosis Using Endoscopic Nasopancreatic Drainage for Early Diagnosis of Pancreatic Cancer

Pancreas ◽  
2012 ◽  
Vol 41 (4) ◽  
pp. 523-529 ◽  
Author(s):  
Tomohiro Iiboshi ◽  
Keiji Hanada ◽  
Toshikatsu Fukuda ◽  
Shuji Yonehara ◽  
Tamito Sasaki ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Early Diagnosis ◽  
Endoscopic Nasopancreatic Drainage ◽  
Nasopancreatic Drainage

scholarly journals Roles of ERCP in the Early Diagnosis of Pancreatic Cancer

Diagnostics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 30 ◽  
Author(s):  
Keiji Hanada ◽  
Tomoyuki Minami ◽  
Akinori Shimizu ◽  
Motomitsu Fukuhara ◽  
Shigeki Yano ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Early Diagnosis ◽  
Early Stage ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Multicenter Studies ◽  
Cross Sectional ◽  
Cytologic Examination ◽  
Endoscopic Nasopancreatic Drainage ◽  
Nasopancreatic Drainage ◽  
Small Pancreatic Cancer

It has been reported that endoscopic retrograde cholangiopancreatography (ERCP) is of value in evaluating precise pancreatograms of the pancreatic duct (PD). Recently, institutions have tended to perform magnetic resonance cholangiopancreatography (MRCP) for the diagnosis of PD due to post-ERCP pancreatitis (PEP). In small pancreatic cancer (PC), including PC in situ (PCIS) which is undetectable on cross sectional images, endoscopic ultrasonography (EUS) and MRCP serve important roles in detecting local irregular stenosis of the PD or small cystic lesions. Subsequently, ERCP and associated serial pancreatic juice aspiration cytologic examination (SPACE) obtained by endoscopic nasopancreatic drainage (ENPD) may be useful in the diagnosis of very early-stage PC. Further prospective multicenter studies are required to establish a standard method of SPACE for the early diagnosis of PC.

Exosomes in pancreatic juice as valuable source of biomarkers for early diagnosis of pancreatic cancer

2017 ◽  
Vol 6 (S8) ◽  
pp. S1339-S1351 ◽  
Author(s):  
Zarin Nuzhat ◽  
Carlos Palma ◽  
Gregory E. Rice ◽  
Virendra Joshi ◽  
Carlos Salomon
Keyword(s):  
Pancreatic Cancer ◽  
Early Diagnosis ◽  
Pancreatic Juice ◽  
Valuable Source

A subsegmental pancreatectomy performed for carcinoma in situ limited to the proximal half of the pancreatic head with the aid of intraoperative 4-segment cytology for pancreatic juice—a case report

Surgery ◽  
2005 ◽  
Vol 138 (5) ◽  
pp. 947-950
Author(s):  
Norikatsu Miyoshi ◽  
Osamu Ishikawa ◽  
Hiroaki Ohigashi ◽  
Hidetoshi Eguchi ◽  
Shingi Imaoka ◽  
...  
Keyword(s):  
Case Report ◽  
Pancreatic Juice ◽  
Carcinoma In Situ ◽  
Pancreatic Head ◽  
Proximal Half

In Situ Telomerase Activity in Pancreatic Juice May Discriminate Pancreatic Cancer From Other Pancreatic Diseases

Pancreas ◽  
2008 ◽  
Vol 36 (3) ◽  
pp. 236-240 ◽  
Author(s):  
Hiroyuki Uehara ◽  
Akihiko Nakaizumi ◽  
Hiroyasu Iishi ◽  
Akemi Takenaka ◽  
Hidetoshi Eguchi ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Pancreatic Juice ◽  
Telomerase Activity ◽  
Pancreatic Diseases

EARLY DIAGNOSIS OF ORAL CANCER IN PATIENTS WITH FANCONI ANEMIA: 2 CASES OF CARCINOMA IN SITU

2020 ◽  
Vol 129 (1) ◽  
pp. e59
Author(s):  
BÁRBARA SOLDATELLI BALLARDIN ◽  
ARTHUR MAGNO MEDEIROS DE ARAÚJO ◽  
ROBERTA TARGA STRAMANDINOLI-ZANICOTTI ◽  
JOSÉ MIGUEL AMENÁBAR CÉSPEDES ◽  
JULIANA LUCENA SCHUSSEL ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Early Diagnosis ◽  
Fanconi Anemia ◽  
Carcinoma In Situ

Transoral Laser Surgery for Early Glottic Carcinoma: A Single Surgeon Experience of 101 Consecutive Cases

ORL ◽  
2020 ◽  
pp. 1-6
Author(s):  
Kerem Ozturk ◽  
Goksel Turhal
Keyword(s):  
Overall Survival ◽  
Carcinoma In Situ ◽  
Early Stage ◽  
Case Series ◽  
Disease Free Survival ◽  
Glottic Carcinoma ◽  
Free Survival ◽  
Surgeon Experience ◽  
Disease Free

<b><i>Purpose:</i></b> Investigate the clinical and oncological results of early-stage glottic laryngeal carcinoma patients performed by a single surgeon. <b><i>Methods:</i></b> This study was carried out at a tertiary academic center. A total of 101 patients were included (92 males [91.1%], 9 females [8.9%]). Mean age was 62.98 ± 10.2 years (range 33–87). Recurrence, disease-free survival, overall survival, laryngeal preservation rates were analyzed. <b><i>Results:</i></b> Tumor stage was Tis (carcinoma in situ) in 11 patients (10.9%), T1a in 66 patients (65.3%), T1b in 12 patients (11.9%), and T2 in 12 patients (11.9%). Postoperative pathology was squamous cell carcinoma in 69 patients (68.3%), carcinoma in situ in 26 patients (25.7%), and high-grade dysplasia in 6 patients (5.9%). Five patients (5.0%) underwent type 1, 7 (6.9%) type 2, 45 (44.6%) type 3, 24 (23.8%) type 4, 6 (5.9%) type 5a, 8 (7.9%) type 5c, 4 (4.0%) type 5d, and 2 (2.0%) type 6 cordectomy. Median follow-up time was 30 months (range 14–66). There were 5 recurrences (5.0%). Three-year disease-free survival was 94.4%. Three-year disease-free survival for stage I and II patients was 94.9 and 91.7%, respectively. Overall survival was 93.8%. Only 1 patient died related to cardiovascular disease. Disease-specific survival was 100%. <b><i>Conclusions:</i></b> In conclusion, this is a large case series with good oncological outcomes presented with the perspective of a single surgeon. The data of the study is in accordance with the previous reports.

Contribution of Cytology, Colposcopy, Target Biopsy and Conization to the Early Diagnosis of Precancerous and Cancerous Lesions of the Cervix Uteri

1978 ◽  
Vol 64 (4) ◽  
pp. 389-398 ◽  
Author(s):  
Silvia Cecchini ◽  
Lucia Bonardi ◽  
Gioia Cipparrone ◽  
Mario Ottaviano ◽  
Gabriella Pieroni
Keyword(s):  
Early Diagnosis ◽  
Diagnostic Accuracy ◽  
Carcinoma In Situ ◽  
Invasive Carcinoma ◽  
Diagnostic Methods ◽  
Cervix Uteri ◽  
Cone Biopsy ◽  
Valid Test ◽  
Target Biopsy

The study is based on. 334 cytologic suspect or positive women observed in the area of Florence. Cytologic diagnoses of dysplasia, carcinoma in situ (CIS), and invasive carcinoma are related to the histologic reports. To the same histologic reports are related the colposcopic aspects. Lastly, diagnoses made by target biopsy are compared with the final diagnoses made by cone biopsy. The 3 diagnostic methods and their diagnostic accuracy are then compared. As regards dysplasia, the diagnostic precision of cytology is 40.2% and for target biopsy is 76.9%. In the diagnosis of CIS, cytology shows a diagnostic accuracy (77.7%) that is a little lower than that of target biopsy (81.7%). In invasive carcinoma, cytology has a good diagnostic precision (88.2%), which becomes 100% if the diagnosis is made by target biopsy. The correlation between colposcopic aspects and histologic reports is not very reliable. We conclude that cytology is a valid test in an extensive mass screening, that colposcopy is essential to execute target biopsy, and that the latter is useful in defining dysplasia and invasive carcinoma diagnoses. On the contrary, in the case of CIS, target biopsy does not greatly increase cytology diagnostic precision.

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