scholarly journals Correction to: PET imaging of sympathetic innervation with [18F]Flubrobenguane vs [11C]mHED in a patient with ischemic cardiomyopathy

2020 ◽  
Vol 27 (2) ◽  
pp. 702-702
Author(s):  
Jason G. E. Zelt ◽  
Lisa M. Mielniczuk ◽  
Cesare Orlandi ◽  
Simon Robinson ◽  
Tayebeh Hadizad ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Ischemic Cardiomyopathy ◽  
Sympathetic Innervation

PET imaging of sympathetic innervation with [18F]Flurobenguan vs [11C]mHED in a patient with ischemic cardiomyopathy

2018 ◽  
Vol 26 (6) ◽  
pp. 2151-2153 ◽  
Author(s):  
Jason G. E. Zelt ◽  
Lisa M. Mielniczuk ◽  
Cesare Orlandi ◽  
Simon Robinson ◽  
Tayebeh Hadizad ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Ischemic Cardiomyopathy ◽  
Sympathetic Innervation

F-18 meta-fluorobenzylguanidine PET imaging of myocardial sympathetic innervation

2022 ◽  
Author(s):  
Milan Grkovski ◽  
Pat B. Zanzonico ◽  
Shakeel Modak ◽  
John L. Humm ◽  
Jagat Narula ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Sympathetic Innervation ◽  
Myocardial Sympathetic Innervation

scholarly journals TRACER KINETICS OF FLUORINE-18 LMI1195 COMPARED TO CARBON-11 HYDROXYEPHEDRINE FOR PET IMAGING OF SYMPATHETIC INNERVATION.

2018 ◽  
Vol 34 (10) ◽  
pp. S117-S118 ◽  
Author(s):  
J. Zelt ◽  
J. Renaud ◽  
L. Mielniczuk ◽  
L. Garrard ◽  
C. Orlandi ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Sympathetic Innervation ◽  
Tracer Kinetics ◽  
Kinetics Of

scholarly journals Global cardiac sympathetic denervation is associated with diffuse myocardial fibrosis in non-ischemic cardiomyopathy

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
HS Chen ◽  
C Jungen ◽  
Y Kimura ◽  
P Dibbets-Schneider ◽  
SRD Piers ◽  
...  
Keyword(s):  
Linear Relationship ◽  
Myocardial Fibrosis ◽  
Ischemic Cardiomyopathy ◽  
Sympathetic Innervation ◽  
Sympathetic Denervation ◽  
Cardiac Sympathetic Innervation ◽  
Funding Sources ◽  
Voltage Mapping ◽  
Heart To Mediastinum Ratio ◽  
Cardiac Sympathetic Denervation

Abstract Funding Acknowledgements Type of funding sources: None. Background   Occurrence of ventricular tachycardias (VT) has been related to changes in sympathetic innervation and myocardial tissue in ischemic cardiomyopathy. In non-ischemic cardiomyopathy (NICM) patients with VT, the relation between global cardiac sympathetic innervation and non-ischemic fibrosis is less clear. The current gold standard in electrophysiology to identify non-ischemic fibrosis relies on unipolar endocardial voltage mapping. Objective To establish the relationship between global cardiac sympathetic innervation and global fibrosis. Methods 29 patients (93% male, 58 ± 14 years, mean LVEF 38%±13) from the ‘Leiden Nonischemic Cardiomyopathy Study’ undergoing VT ablation between 2011-2018 were included. Endocardial voltage mapping was performed and the mean endocardial unipolar voltage (UV) was taken as a surrogate for global fibrosis. Global cardiac sympathetic innervation was analyzed by 123-I-MIBG imaging using heart-to-mediastinum ratio (HMR). A cut-off of 1.8 was used to delineate between normal (>1.8) and denervated (<1.8). HMR was correlated with mean UV. Results For patients with global cardiac sympathetic denervation a linear relationship was present between HMR and mean UV (R = 0.5278, P = 0.0431. There was no significant linear relationship for patients with normal cardiac sympathetic innervation between HMR and mean UV (R=-0.1696, P = 0.5795). Conclusion Global cardiac sympathetic denervation is related to myocardial fibrosis in patients with NICM and VT. The data support an interplay between denervation and fibrosis which may contribute to arrhythmogeneity, as observed in ICM. Abstract Figure.

Regional Distribution of Fluorine-18-Flubrobenguane and Carbon-11-Hydroxyephedrine for Cardiac PET Imaging of Sympathetic Innervation

2020 ◽  
Author(s):  
Jason G.E. Zelt ◽  
Deron Britt ◽  
Braeden A. Mair ◽  
Benjamin H. Rotstein ◽  
Sarah Quigley ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Sympathetic Innervation ◽  
Regional Distribution ◽  
Cardiac Pet ◽  
Cardiac Pet Imaging
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