scholarly journals Sevoflurane and nitrous oxide exert cardioprotective effects against hypoxia-reoxygenation injury in the isolated rat heart

Author(s):  
Chunhong Jin ◽  
Seijiro Sonoda ◽  
Liu Fan ◽  
Makino Watanabe ◽  
Toyoki Kugimiya ◽  
...  
2019 ◽  
Author(s):  
Elena Kharkovskaya ◽  
Grigory V. Osipov ◽  
Irina V. Mukhina

AbstractThe aim of the study was to apply the multi-electrode mapping method to investigate the effect of 2-aminoethoxydiphenyl borate (2-apb) on the electrical activity and vessels of the isolated rat heart under hypoxia/reoxygenation injury (H/R). To date, the ability to influence on the calcium currents and condition of gap junctions has been shown for 2-apb. Changes in the intracellular calcium concentration in the heart play the pivotal role in the development of H/R.As a result, it was shown that 2-apb influences on the myocardial conduction velocity, sinus rhythm and coronary blood flow in the isolated rat heart. 2-apb caused heart fibrillation during normoxia but not under hypoxia, and attenuated the effect of the H/R on heart rate and vascular function.


2002 ◽  
Vol 89 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Kazuhiko Saeki ◽  
Ichiro Obi ◽  
Noriko Ogiku ◽  
Munekazu Shigekawa ◽  
Toshiaki Imagawa ◽  
...  

Life Sciences ◽  
2021 ◽  
Vol 264 ◽  
pp. 118659
Author(s):  
Maryam Rameshrad ◽  
Seyedeh Farzaneh Omidkhoda ◽  
Bibi Marjan Razavi ◽  
Hossein Hosseinzadeh

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Yosuke Nakadate ◽  
Hiroaki Sato ◽  
Takeshi Oguchi ◽  
Tamaki Sato ◽  
Akiko Kawakami ◽  
...  

1997 ◽  
Vol 35 (1) ◽  
pp. 57-64 ◽  
Author(s):  
GIANLUCA LOZZA ◽  
ANNAMARIA CONTI ◽  
ENNIO ONGINI ◽  
ANGELA MONOPOLI

1988 ◽  
Vol 63 (6) ◽  
pp. 1044-1052 ◽  
Author(s):  
A M Keller ◽  
R M Clancy ◽  
M L Barr ◽  
C C Marboe ◽  
P J Cannon

2017 ◽  
Vol 90 ◽  
pp. 194-202 ◽  
Author(s):  
Francesca Tullio ◽  
Claudia Penna ◽  
Karine Cabiale ◽  
Saveria Femminò ◽  
Marco Galloni ◽  
...  

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