In vitro efficacy of polymer coated miltefosine drug against leishmania tropica

2021 ◽  
Author(s):  
Mehvish Khokhar ◽  
Muhammad Adnan Shereen ◽  
Momin Khan ◽  
Rahat Ullah Khan ◽  
Aamir Sohail ◽  
...  
Keyword(s):  
Leishmania Tropica

scholarly journals EAPB0503: an imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica

2020 ◽  
Vol 13 (12) ◽  
pp. 2112
Author(s):  
Rana El Hajj ◽  
Hanady Bou Youness ◽  
Laurence Lachaud ◽  
Patrick Bastien ◽  
Carine Masquefa ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Major ◽  
Vitro Activity ◽  
Leishmania Tropica ◽  
In Vitro Activity

Inhibition by Dications of In Vitro Growth of Leishmania major and Leishmania tropica: Causative Agents of Old World Cutaneous Leishmaniasis

2008 ◽  
Vol 94 (3) ◽  
pp. 743-749 ◽  
Author(s):  
Alexa C. Rosypal ◽  
Karl A. Werbovetz ◽  
Manar Salem ◽  
Chad E. Stephens ◽  
Arvind Kumar ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Major ◽  
Leishmania Tropica ◽  
In Vitro Growth ◽  
Old World ◽  
Causative Agents

scholarly journals EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica

2018 ◽  
Vol 12 (11) ◽  
pp. e0006854 ◽  
Author(s):  
Rana El Hajj ◽  
Hanady Bou Youness ◽  
Laurence Lachaud ◽  
Patrick Bastien ◽  
Carine Masquefa ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Major ◽  
Vitro Activity ◽  
Leishmania Tropica ◽  
In Vitro Activity

scholarly journals Activity of purine analogs against Leishmania tropica within human macrophages in vitro.

1983 ◽  
Vol 24 (2) ◽  
pp. 233-236 ◽  
Author(s):  
J D Berman ◽  
L S Lee ◽  
R K Robins ◽  
G R Revankar
Keyword(s):  
Leishmania Tropica ◽  
Human Macrophages ◽  
Purine Analogs

scholarly journals Functional analysis of the murine T lymphocyte immune response to a protozoan parasite, Leishmania tropica

1983 ◽  
Vol 78 (1) ◽  
pp. 105-120 ◽  
Author(s):  
H. D. Engers ◽  
S. G. Coutinho ◽  
G. M. C. de Araújo Lima ◽  
J. A. Louis
Keyword(s):  
T Cell ◽  
Protozoan Parasite ◽  
Delayed Type Hypersensitivity ◽  
Cell Populations ◽  
Leishmania Tropica ◽  
Intracellular Parasites ◽  
Helper Activity ◽  
Cellular Immune ◽  
Parasite Leishmania

The results presented in this review summarize a seirs of experiments designed to characterize the murine T cell imune response to the protozoan parasite Leishmania tropica. Enriched T cell populations and T cell clones specific for L. tropica antigens were derived from lymph nodes of primed mice and maintained in continous culture in vitro. These T lymphocytes were shown (A) to express the Lyt 1+ 3- cell surface phenotype, (B) to proliferate specifically in vitro in response to parasite antigens, together with a source of irradiated syngeneic macrophages, (C) to transfer antigen-specific delayed-type hypersensitivity (DTH) responses to normal syngeneic mice, (D) to induce specific activation of parasitized macrophages in vitro resulting in the destruction of intracellular parasites, (E) to provide specific helper activity for antibody responses in vitro in a hapten-carrier system. Protection studies using these defiened T cell populations should allow the characterization of parasite antigen(s) implicated in the induction of cellular immune responses beneficial for the host.

scholarly journals 1147 THE ENHANCING EFFECT OF INTERFERON-β AND γ ON THE KILLING OF LEISHMANIA TROPICA MAJOR IN HUMAN MONOCYTES IN VITRO

1985 ◽  
Vol 19 (4) ◽  
pp. 302A-302A
Author(s):  
J H Passmell ◽  
R Shor ◽  
J Shoham ◽  
Maureen Hack
Keyword(s):  
Leishmania Tropica ◽  
Human Monocytes ◽  
Interferon Β ◽  
Enhancing Effect

The in vitro Generation and Functional Analysis of Murine T Cell Populations and Clones Specific for a Protozoan Parasite, Leishmania tropica

1982 ◽  
Vol 61 (1) ◽  
pp. 215-243 ◽  
Author(s):  
J.A. Louis ◽  
R.H. Zubler ◽  
S.G. Coutinho ◽  
G. Lima ◽  
R. Behin ◽  
...  
Keyword(s):  
Functional Analysis ◽  
T Cell ◽  
Protozoan Parasite ◽  
Cell Populations ◽  
Leishmania Tropica ◽  
Parasite Leishmania
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