Infection, Alveolar Osteitis, and Adverse Effects Using Metronidazole in Healthy Patients Undergoing Third Molar Surgery: A Meta-analysis

The purpose of this systematic review was to determine the analgesic efficacy and adverse effects of ibuprofen in comparison with other traditional non-opioid analgesics after third molar surgery. A total of 17 full texts were identified in PubMed and assessed using the Cochrane Collaboration’s risk of bias tool by two independent researchers. The sum of pain intensity differences, total pain relief, the overall evaluation, the number of patients requiring rescue analgesics, and adverse effects were collected. Data were analyzed using the Review Manager Software 5.3. for Windows. A total of 15 articles met the criteria. The qualitative and quantitative analysis showed that ibuprofen is more effective to relieve post-operative dental pain than acetaminophen, meclofenamate, aceclofenac, bromfenac, and aspirin. Moreover, ibuprofen and traditional non-steroidal anti-inflammatory drugs have a similar safety profile. In conclusion, ibuprofen 400 mg appears to have good analgesic efficacy and a safety profile similar to other traditional non-steroidal anti-inflammatory drugs after third molar surgery.

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Does the piezoelectric surgical technique produce fewer postoperative sequelae after lower third molar surgery than conventional rotary instruments? A systematic review and meta analysis

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ijom.2015.10.005 ◽

2016 ◽

Vol 45 (3) ◽

pp. 383-391 ◽

Cited By ~ 23

Author(s):

E.A. Al-Moraissi ◽

Y.A. Elmansi ◽

Y.A. Al-Sharaee ◽

A.E. Alrmali ◽

A.S. Alkhutari

Keyword(s):

Systematic Review ◽

Surgical Technique ◽

Meta Analysis ◽

Third Molar ◽

Third Molar Surgery ◽

Rotary Instruments

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Randomized Study on Postoperative Intra-alveolar Betadine Irrigation Versus Chlorhexidine Irrigation on the Incidence of Occurrence of Alveolar Osteitis After Mandibular Third Molar Surgery

Journal of Maxillofacial and Oral Surgery ◽

10.1007/s12663-020-01349-4 ◽

2020 ◽

Author(s):

Rajat Mohanty ◽

Chhaya Jha

Keyword(s):

Randomized Study ◽

Third Molar ◽

Third Molar Surgery ◽

Mandibular Third Molar ◽

Alveolar Osteitis ◽

Mandibular Third Molar Surgery

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Application of propolis extract, nanovitamin C and nanovitamin E to prevent alveolar osteitis after impacted lower third molar surgery. A randomized, double-blind, split-mouth, pilot study

Medicina Oral Patología Oral y Cirugia Bucal ◽

10.4317/medoral.23915 ◽

2021 ◽

pp. e118-e125

Author(s):

J. González-Serrano ◽

RM. López-Pintor ◽

R. Cecilia-Murga ◽

J. Torres ◽

G. Hernández ◽

...

Keyword(s):

Pilot Study ◽

Third Molar ◽

Third Molar Surgery ◽

Double Blind ◽

Propolis Extract ◽

Alveolar Osteitis

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Panoramic versus CBCT used to reduce inferior alveolar nerve paresthesia after third molar extractions: a systematic review and meta-analysis

Dentomaxillofacial Radiology ◽

10.1259/dmfr.20190265 ◽

2020 ◽

Vol 49 (4) ◽

pp. 20190265

Author(s):

Nathalia Calzavara Del Lhano ◽

Rosangela Almeida Ribeiro ◽

Carolina Castro Martins ◽

Neuza Maria Souza Picorelli Assis ◽

Karina Lopes Devito

Keyword(s):

Systematic Review ◽

Panoramic Radiography ◽

Meta Analysis ◽

Inferior Alveolar Nerve ◽

Third Molar ◽

Risk Of Bias ◽

Third Molar Surgery ◽

Reference List ◽

Significant Heterogeneity ◽

Eligibility Criteria

Objectives: The aim of this systematic review was to verify whether CBCT in comparison with panoramic radiography reduced the cases of temporary paresthesias of the inferior alveolar nerve (IAN) associated with third molar extractions. Methods: The literature search included five databases (PubMed, Scopus, Web of Science, Cochrane, SciELO), in addition to gray literature and hand search of reference list of included studies. Two reviewers independently screened titles/abstracts, and full texts according to eligibility criteria, extracted data and evaluated risk of bias through Revised Cochrane Risk of Bias Tool for Randomized Trials (RoB 2.0). Data were meta-analyzed by comparing CBCT versus panoramic radiographs for number of events (temporary paresthesia after third molar surgery). Fixed effect model was used for non-significant heterogeneity; relative risk (RR) and 95% CI were calculated. The certainty of evidence was evaluated by Grading of Recommendations, Assessment, Development, and Evaluation (GRADE). Results: Four randomized controlled trials (RCTs) were included in meta-analysis, and for the majority of domains they presented low risk of bias. RR was 1.23 (95% IC: 0.75–2.02; I2: 0%; p = 0.43) favouring panoramic radiography, but without significant effect, and with moderate certainty of evidence. Conclusions: We concluded that both interventions had a similar ability to reduce temporary paresthesia of the IAN after third molar surgery with moderate certainty of evidence.

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