Carotid Endarterectomy and Stenting in a Chinese Population: Safety Outcome of the Revascularization of Extracranial Carotid Artery Stenosis Trial

2020 ◽  
Author(s):  
Bin Yang ◽  
◽  
Yan Ma ◽  
Tao Wang ◽  
Yanfei Chen ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Endarterectomy ◽  
Carotid Artery Stenosis ◽  
Chinese Population ◽  
Artery Stenosis ◽  
Extracranial Carotid Artery ◽  
Safety Outcome

Perioperative complications in bilateral carotid endarterectomy for patients with bilateral carotid artery stenosis

1997 ◽  
Vol 99 ◽  
pp. S63
Author(s):  
Shugo Takikawa ◽  
Kiyohiro Houkin ◽  
Satoshi Ushikosi ◽  
Hisatoshi Saitoh ◽  
Takeshi Kashiwaba ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Endarterectomy ◽  
Carotid Artery Stenosis ◽  
Perioperative Complications ◽  
Artery Stenosis ◽  
Bilateral Carotid ◽  
Bilateral Carotid Artery

Transcarotid Artery Revascularization and Advances in Vascular Surgery for Carotid Artery Disease

2021 ◽  
Author(s):  
James Hu ◽  
◽  
Andy Sohn ◽  
Justin George ◽  
Rajesh Malik ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Vascular Surgery ◽  
Carotid Endarterectomy ◽  
Surgical Management ◽  
Carotid Artery Stenosis ◽  
Carotid Artery Stenting ◽  
Carotid Artery Disease ◽  
Artery Stenosis ◽  
Cerebrovascular Accidents ◽  
Artery Disease

Carotid artery atherosclerotic disease impacts over 2 million Americans annually. Since the advent of the carotid endarterectomy by Debakey in 1953, the surgical management of carotid artery stenosis has prevented cerebrovascular accidents. The technology utilized to manage carotid artery stenosis continued to evolve with the utilization of carotid artery stenting in 1989 and more recently transcarotid artery revascularization (TCAR). This review discusses the modern management of carotid artery stenosis with an emphasis on transcarotid artery revascularization (TCAR) and reversal of flow for reversal of flow for embolic protection.

ECAS score: a web-based risk model to predict moderate and severe extracranial carotid artery stenosis

2018 ◽  
Vol 40 (4) ◽  
pp. 249-257 ◽  
Author(s):  
Yinglin Yan ◽  
Suying Gao ◽  
Hongna Yang ◽  
Shangmin Qin ◽  
Fang Li ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Risk Model ◽  
Artery Stenosis ◽  
Web Based ◽  
Extracranial Carotid Artery

Abstract 113: Platelet and Monocyte Activity in Carotid Artery Stenosis Treated with Carotid Endarterectomy

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Arvind Reddy Devanabanda ◽  
Caron Rockman ◽  
Nicole Allen ◽  
Maya Rubin ◽  
Binita Shah ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Endarterectomy ◽  
Carotid Artery Stenosis ◽  
Healthy Subjects ◽  
Artery Stenosis ◽  
Monocyte Subsets ◽  
Platelet Activity ◽  
Platelet Surface ◽  
Inflammatory Monocytes ◽  
Anti Inflammatory

Background: Carotid artery stenosis (CAS) is a marker of atherosclerosis, a disease mediated by abnormalities in platelet and monocyte function, and a significant cause of stroke. Moreover, the effect of carotid artery revascularization via carotid endarterectomy (CEA) on platelet and monocyte markers is unknown. Objective: This study aims to investigate platelet activity, monocyte subsets and monocyte platelet aggregates (MPA) in CAS and changes with CEA. Methods: This prospective cohort study evaluated 48 patients who underwent non emergent CEA. Peripheral venous blood samples were obtained before, immediately postoperative and at 24 hours postoperative. Twenty healthy subjects served as controls. Platelet surface expression of P-selectin and PAC-1, monocyte subsets, and MPA were assessed using flow cytometry. Three distinct monocyte subsets were measured: anti-inflammatory (i.e. classical CD14 ++ CD16 - ) and pro-inflammatory (i.e. intermediate CD14 ++ CD16 + and nonclassical CD14 + CD16 ++ ) monocytes. Differences between two matched samples and between the study and control groups were statistically analyzed. Results: Compared to healthy subjects, CAS subjects had significantly greater markers of platelet activity (P-selectin [p=0.003] and PAC-1 [p=0.01]), pro-inflammatory monocytes (intermediate [p<0.0001] and nonclassical [p=0.009]) and MPA (p=0.0002). Following CEA, anti-inflammatory monocytes increased and pro-inflammatory monocytes decreased (Figure 1A). Platelet expression of P-selectin and MPA did not change, while PAC-1 transiently increased but then returned to baseline by 24 hours postoperative (Figure 1B &C). Conclusions: Subjects with CAS have elevated markers of thrombosis, inflammation, and their interface. However, only the pro-inflammatory monocytes are significantly reduced following CEA. Future studies investigating the clinical consequences of this reduction are warranted.

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