Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice

2011 ◽  
Vol 67 (4) ◽  
pp. 551-558 ◽  
Author(s):  
Carmen Vida ◽  
Isabel Corpas ◽  
Mónica De la Fuente ◽  
Eva M. González
Keyword(s):  
Lipid Peroxidation ◽  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Female Mice ◽  
Xanthine Oxidase Activity ◽  
Age Related ◽  
Age Related Changes

Effect of acetyl-l-carnitine on lipid peroxidation and xanthine oxidase activity in rat skeletal muscle

1993 ◽  
Vol 18 (11) ◽  
pp. 1157-1162 ◽  
Author(s):  
C. Di Giacomo ◽  
F. Latteri ◽  
C. Fichera ◽  
V. Sorrenti ◽  
A. Campisi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lipid Peroxidation ◽  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Rat Skeletal Muscle ◽  
Xanthine Oxidase Activity

scholarly journals Xanthine oxidase activity in patients with age-related cataract associated with hypertension

2018 ◽  
Vol 51 (5) ◽  
Author(s):  
B. Kisic ◽  
D. Miric ◽  
L. Zoric ◽  
J.V. Rasic ◽  
R. Grbic ◽  
...  
Keyword(s):  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Xanthine Oxidase Activity ◽  
Age Related

Xanthine oxidase and activated neutrophils cause oxidative damage to skeletal muscle after contractile claudication

2004 ◽  
Vol 286 (1) ◽  
pp. H252-H256 ◽  
Author(s):  
A. R. Judge ◽  
S. L. Dodd
Keyword(s):  
Skeletal Muscle ◽  
Lipid Peroxidation ◽  
Oxidative Damage ◽  
Xanthine Oxidase ◽  
Muscle Damage ◽  
Protein Oxidation ◽  
Oxidase Activity ◽  
Neutrophil Infiltration ◽  
Xanthine Oxidase Activity ◽  
Infiltration Control

We previously showed oxidative damage and edema within skeletal muscle after contractile claudication. To investigate the sources of this oxidative damage in the gastrocnemius muscle, we administered allopurinol (Allo, to inhibit xanthine oxidase) and cyclophosphamide (Cyclo, to deplete neutrophils) before inducing contractile claudication in male Sprague Dawley rats. Contractile claudication (ligated stimulated, LS) caused a significant increase in xanthine oxidase activity [sham ligated stimulated (SS) = 2.57 ± 0.07; LS = 3.22 ± 0.07] and neutrophil infiltration (SS = 0.47 ± 0.03; LS = 0.91 ± 0.10) compared with controls (SS), and this was associated with increased lipid peroxidation, protein oxidation, muscle damage, and edema. Pretreatment with Allo attenuated the increase in xanthine oxidase activity and attenuated lipid hydroperoxides (control LS = 12.85 ± 0.50; Allo LS = 9.96 ± 0.71), muscle damage, and neutrophil infiltration (control LS = 0.91 ± 0.10; Allo LS = 0.61 ± 0.07). This latter finding suggests that xanthine oxidase-derived oxidants are chemotactic to neutrophils. Pretreatment with Cyclo reduced neutrophil infiltration (control LS = 0.91 ± 0.10; Cyclo LS = 0.55 ± 0.02) and attenuated lipid peroxidation (control LS = 12.85 ± 0.50; Cyclo LS = 6.462 ± 0.62), protein oxidation (control LS = 2.59 ± 0.47; Cyclo LS = 1.77 ± 0.60), muscle damage, and edema. Together, these data indicate that contractile claudication causes an increase in xanthine oxidase activity and neutrophils in muscle and that inhibition of these oxidant sources protects against oxidative stress, muscle damage, and edema.

Age-related increase in xanthine oxidase activity in human plasma and rat tissues

2007 ◽  
Vol 41 (11) ◽  
pp. 1195-1200 ◽  
Author(s):  
Rafael Aranda ◽  
Elena Doménech ◽  
Ariana Diana Rus ◽  
José T. Real ◽  
Juan Sastre ◽  
...  
Keyword(s):  
Xanthine Oxidase ◽  
Human Plasma ◽  
Oxidase Activity ◽  
Rat Tissues ◽  
Xanthine Oxidase Activity ◽  
Age Related ◽  
Related Increase

scholarly journals HYDROXYLAMINE INHIBITION OF XANTHINE OXIDASE ACTIVITY

1956 ◽  
Vol 219 (1) ◽  
pp. 375-382 ◽  
Author(s):  
L.S. Dietrich ◽  
Eleanor Borries
Keyword(s):  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Xanthine Oxidase Activity

Xanthine oxidase activity in the brain

1968 ◽  
Vol 24 (11) ◽  
pp. 1101-1102 ◽  
Author(s):  
G. G. Villela
Keyword(s):  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Xanthine Oxidase Activity ◽  
The Brain
Sign in / Sign up

Export Citation Format

Share Document