Comparison of three human liver cell lines for in vitro drug-induced liver injury assessment: Huh7, HepaRG, and stem cell-derived hepatocytes

2019 ◽  
Vol 15 (3) ◽  
pp. 271-285
Author(s):  
So Yoon Yun ◽  
Ju Yeun Kim ◽  
Moon Jung Back ◽  
Hee Soo Kim ◽  
Hae Chan Ha ◽  
...  
Keyword(s):  
Stem Cell ◽  
Liver Injury ◽  
Cell Lines ◽  
Liver Cell ◽  
Human Liver ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Human Liver Cell ◽  
Injury Assessment

Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins

2009 ◽  
Vol 37 (12) ◽  
pp. 2383-2392 ◽  
Author(s):  
Toru Usui ◽  
Masashi Mise ◽  
Takanori Hashizume ◽  
Masashi Yabuki ◽  
Setsuko Komuro
Keyword(s):  
Liver Injury ◽  
Human Liver ◽  
Covalent Binding ◽  
Drug Induced ◽  
Drug Induced Liver Injury

In vitro toxicity of 7H-dibenzo[c,g]carbazole in human liver cell lines

2002 ◽  
Vol 16 (3) ◽  
pp. 235-243 ◽  
Author(s):  
T. O'Brien ◽  
J. Schneider ◽  
D. Warshawsky ◽  
K. Mitchell
Keyword(s):  
Cell Lines ◽  
Liver Cell ◽  
Human Liver ◽  
In Vitro Toxicity ◽  
Human Liver Cell

The HepaRG cell line, a superior in vitro model to L-02, HepG2 and hiHeps cell lines for assessing drug-induced liver injury

2016 ◽  
Vol 32 (1) ◽  
pp. 37-59 ◽  
Author(s):  
Yu Wu ◽  
Xing-chao Geng ◽  
Ju-feng Wang ◽  
Yu-fa Miao ◽  
Yan-li Lu ◽  
...  
Keyword(s):  
Liver Injury ◽  
Cell Line ◽  
Cell Lines ◽  
In Vitro Model ◽  
Drug Induced ◽  
Heparg Cell ◽  
Drug Induced Liver Injury ◽  
Heparg Cell Line ◽  
Vitro Model

Human liver cell cultivation for long-term in vitro toxicity studies in a miniaturized multi-compartment 3D bioreactor system

2011 ◽  
Vol 49 (01) ◽  
Author(s):  
SA Hoffmann ◽  
M Lübberstedt ◽  
U Müller-Vieira ◽  
D Knobeloch ◽  
A Nüssler ◽  
...  
Keyword(s):  
Liver Cell ◽  
Human Liver ◽  
In Vitro Toxicity ◽  
Cell Cultivation ◽  
Toxicity Studies ◽  
Human Liver Cell ◽  
Bioreactor System

Drug-induced liver injury classification model based on in vitro human transcriptomics and in vivo rat clinical chemistry data

2014 ◽  
Vol 2 (4) ◽  
pp. 63-70 ◽  
Author(s):  
Danyel Jennen ◽  
Jan Polman ◽  
Mark Bessem ◽  
Maarten Coonen ◽  
Joost van Delft ◽  
...  
Keyword(s):  
Liver Injury ◽  
Clinical Chemistry ◽  
Classification Model ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Chemistry Data ◽  
Model Based ◽  
Injury Classification

scholarly journals Expression of mediators of purinergic signaling in human liver cell lines

2014 ◽  
Vol 10 (4) ◽  
pp. 631-638 ◽  
Author(s):  
Jessica R. Goree ◽  
Elise G. Lavoie ◽  
Michel Fausther ◽  
Jonathan A. Dranoff
Keyword(s):  
Cell Lines ◽  
Liver Cell ◽  
Human Liver ◽  
Purinergic Signaling ◽  
Human Liver Cell
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