Effectiveness of mechanical bowel preparation versus no preparation on anastomotic leakage in colorectal surgery: a systematic review and meta-analysis

2018 ◽  
Vol 71 (2) ◽  
pp. 227-236 ◽  
Author(s):  
Jobbe P. L. Leenen ◽  
Judith E. K. R. Hentzen ◽  
Henrietta D. L. Ockhuijsen
Keyword(s):  
Systematic Review ◽  
Colorectal Surgery ◽  
Anastomotic Leakage ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation

Does Mechanical Bowel Preparation Reduce the Risk of Developing Infectious Complications in Pediatric Colorectal Surgery? A Systematic Review and Meta-Analysis

2018 ◽  
Vol 203 ◽  
pp. 288-293.e1
Author(s):  
Koen Zwart ◽  
Dirk-Jan Van Ginkel ◽  
Caroline C.C. Hulsker ◽  
Marieke J. Witvliet ◽  
Maud Y.A. Van Herwaarden-Lindeboom
Keyword(s):  
Systematic Review ◽  
Colorectal Surgery ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation ◽  
Infectious Complications

The value of mechanical bowel preparation prior to pediatric colorectal surgery: a systematic review and meta-analysis

2018 ◽  
Vol 34 (12) ◽  
pp. 1305-1320 ◽  
Author(s):  
Maarten Janssen Lok ◽  
Hiromu Miyake ◽  
Joshua S. O’Connell ◽  
Shogo Seo ◽  
Agostino Pierro
Keyword(s):  
Systematic Review ◽  
Colorectal Surgery ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation

Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials on the Role of Mechanical Bowel Preparation Before Colorectal Surgery

2009 ◽  
Vol 249 (2) ◽  
pp. 203-209 ◽  
Author(s):  
Karem Slim ◽  
Eric Vicaut ◽  
Marie-Véronique Launay-Savary ◽  
Caroline Contant ◽  
Jacques Chipponi
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Colorectal Surgery ◽  
Bowel Preparation ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation

TP7.2.16 Systematic review and meta analysis of pre operative antibiotics and bowel preparation on ileus following colorectal resection

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Michael Kelly ◽  
Gerard McKnight ◽  
Alisdair J. Scott
Keyword(s):  
Systematic Review ◽  
Cohort Studies ◽  
Risk Ratio ◽  
Bowel Preparation ◽  
Colorectal Resection ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation ◽  
Infectious Complications ◽  
Randomised Trials ◽  
Randomised Controlled

Abstract Aims Pre-operative oral antibiotics (OAB) and mechanical bowel preparation (MBP) may reduce rates of post-operative infectious complications following colorectal surgery but their effects on post-operative ileus (POI) are not well-established. We conducted a systematic review and meta-analysis to address this question. Methods Medline and Embase databases were searched to identify randomised controlled trials and cohort studies comparing pre-operative MBP or OAB to control in patients undergoing elective colorectal resection and reporting the rate of POI as an outcome. Risk ratios were pooled using a random-effects model to generate a summary risk ratio and 95% confidence interval. Results Five randomised trials and three cohort studies were included which reported the effect of pre-operative MBP on POI. Some 29056 patients received MBP compared to 13077 who did not. The rates of POI were 10.0% vs 12.0% respectively. Meta-analysis gave a risk ratio of 0.85 (0.80-0.91, p < 0.0001) for the development of POI with MBP versus control. Four randomised trials and four cohort studies were included which reported the effect of pre-operative OAB on POI. Some 9.5% of 19,903 patients receiving OAB developed POI compared to 11.8% of 23,884 control patients. The pooled risk ratio for the development of POI with OAB compared to control was 0.86 (0.81-0.91, p < 0.0001). However, when limiting analyses to randomised trials alone, neither MBP (RR 1.13, 0.67-1.90) nor OAB 1.01, 0.75-1.35) had a significant effect on the rate of POI. Conclusions Pre-operative MBP or OAB may reduce POI following colorectal resection but this has not been confirmed in randomised trials.

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