Up-to-date Systematic Review and Meta-analysis of Therapeutic Hypothermia for Neonatal Encephalopathy: Is the Crown Losing Its Sheen?

2021 ◽  
Vol 58 (12) ◽  
pp. 1189-1191
Author(s):  
Joseph L. Mathew ◽  
Navneet Kaur ◽  
Jeanne M. Dsouza
Keyword(s):  
Systematic Review ◽  
Therapeutic Hypothermia ◽  
Meta Analysis ◽  
Neonatal Encephalopathy

scholarly journals Therapeutic Hypothermia for Neonatal Encephalopathy in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e58834 ◽  
Author(s):  
Shreela S. Pauliah ◽  
Seetha Shankaran ◽  
Angie Wade ◽  
Ernest B. Cady ◽  
Sudhin Thayyil
Keyword(s):  
Systematic Review ◽  
Therapeutic Hypothermia ◽  
Meta Analysis ◽  
Neonatal Encephalopathy ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Melatonin for neuroprotection in neonatal encephalopathy: A systematic review & meta-analysis of clinical trials

2021 ◽  
Vol 31 ◽  
pp. 38-45 ◽  
Author(s):  
Javed Ahmed ◽  
Abdul Kareem Pullattayil S ◽  
Nicola J. Robertson ◽  
Kiran More
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Meta Analysis ◽  
Neonatal Encephalopathy

scholarly journals No Benefit to Prehospital Initiation of Therapeutic Hypothermia in Out-of-hospital Cardiac Arrest: A Systematic Review and Meta-analysis

2014 ◽  
Vol 21 (4) ◽  
pp. 355-364 ◽  
Author(s):  
Benton R. Hunter ◽  
Daniel P. O'Donnell ◽  
Kacy L. Allgood ◽  
Rawle A. Seupaul
Keyword(s):  
Systematic Review ◽  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Meta Analysis ◽  
Hospital Cardiac Arrest

Therapeutic hypothermia for mild neonatal encephalopathy: a systematic review and meta-analysis

2018 ◽  
Vol 105 (2) ◽  
pp. 225-228 ◽  
Author(s):  
Ujwal Kariholu ◽  
Paolo Montaldo ◽  
Theodora Markati ◽  
Peter J Lally ◽  
Russell Pryce ◽  
...  
Keyword(s):  
Usual Care ◽  
Therapeutic Hypothermia ◽  
Data Extraction ◽  
Meta Analysis ◽  
Adverse Outcomes ◽  
Whole Body ◽  
Current Evidence ◽  
Neonatal Encephalopathy ◽  
Medical Subject Headings ◽  
Manual Search

ObjectivesTo examine if therapeutic hypothermia reduces the composite outcome of death, moderate or severe disability at 18 months or more after mild neonatal encephalopathy (NE).Data sourceMEDLINE, Cochrane database, Scopus and ISI Web of Knowledge databases, using ‘hypoxic ischaemic encephalopathy’, ‘newborn’ and ‘hypothermia’, and ‘clinical trials’ as medical subject headings and terms. Manual search of the reference lists of all eligible articles and major review articles and additional data from the corresponding authors of selected articles.Study selectionRandomised and quasirandomised controlled trials comparing therapeutic hypothermia with usual care.Data extractionSafety and efficacy data extracted independently by two reviewers and analysed.ResultsWe included the data on 117 babies with mild NE inadvertently recruited to five cooling trials (two whole-body cooling and three selective head cooling) of moderate and severe NE, in the meta-analysis. Adverse outcomes occurred in 11/56 (19.6%) of the cooled babies and 12/61 (19.7%) of the usual care babies (risk ratio 1.11 (95% CIs 0.55 to 2.25)).ConclusionsCurrent evidence is insufficient to recommend routine therapeutic hypothermia for babies with mild encephalopathy and significant benefits or harm cannot be excluded.

Therapeutic hypothermia after cardiac arrest: A systematic review/meta-analysis exploring the impact of expanded criteria and targeted temperature

Resuscitation ◽  
2016 ◽  
Vol 108 ◽  
pp. 102-110 ◽  
Author(s):  
Aldo L. Schenone ◽  
Aaron Cohen ◽  
Gabriel Patarroyo ◽  
Logan Harper ◽  
XiaoFeng Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Meta Analysis ◽  
Expanded Criteria ◽  
The Impact

Does therapeutic hypothermia benefit adult patients resuscitated from non-VF cardiac arrest? A systematic review and meta-analysis

Resuscitation ◽  
2010 ◽  
Vol 81 (2) ◽  
pp. S67
Author(s):  
Y.M. Kim ◽  
H.W. Yim ◽  
S.H. Jeong ◽  
M.L. Klem ◽  
C.W. Callaway
Keyword(s):  
Systematic Review ◽  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Meta Analysis ◽  
Adult Patients

Predictors of poor neurological outcome in adult comatose survivors of cardiac arrest: A systematic review and meta-analysis. Part 1: Patients not treated with therapeutic hypothermia

Resuscitation ◽  
2013 ◽  
Vol 84 (10) ◽  
pp. 1310-1323 ◽  
Author(s):  
Claudio Sandroni ◽  
Fabio Cavallaro ◽  
Clifton W. Callaway ◽  
Tommaso Sanna ◽  
Sonia D’Arrigo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Neurological Outcome ◽  
Meta Analysis ◽  
Poor Neurological Outcome
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