Mild hyperamylasemia in type 1 diabetic children without diabetic ketoacidosis is associated with C-peptide

2019 ◽  
Vol 40 (2) ◽  
pp. 255-261
Author(s):  
Wei Song ◽  
Dingding Wang ◽  
Yu Qiao ◽  
Jiang Xue ◽  
Guimei Li
2018 ◽  
Vol 03 (02) ◽  
Author(s):  
Abdullah Othman ◽  
Mohammad Ahmed Awwad ◽  
Kamran Mahmood Ahmed Aziz ◽  
Sameera Mohammed Asiri ◽  
Norura Mohammed alqahtani

Author(s):  
Manal Ali Alhomood ◽  
Khalid Yahya Shibli ◽  
Safar Abadi

2021 ◽  
Vol 11 (05) ◽  
pp. 119-128
Author(s):  
Abdulaziz Fahad Al Kaabba ◽  
Bandar Saleh Alzuair ◽  
Yara Faisal AlHarbi ◽  
Juhainah Abdullah Alshehri ◽  
Lujain Habeeb Allowaihiq ◽  
...  

Author(s):  
Nazim Faisal Hamed ◽  
Manal Mohammed E. Alhawiti ◽  
Eman Hamed A. Albalawi ◽  
Lena Defallah G. Alzahrani ◽  
Raghad Mohammed E. Alhawiti ◽  
...  

Background: Diabetic ketoacidosis (DKA) is a common emergency and life-threatening illness. Also, if not detected early, early treatment in the emergency room can cause serious complications. The goal of managing type 1 diabetes is to maintain the correct levels of blood sugar, glycated hemoglobin (HbA1c), blood pressure, lipid levels, and body weight while avoiding hypoglycemia. Treatment of type 1 diabetes requires proper insulin treatment, proper nutrition, physical activity, preventive education, and patient self-care Objective: The purpose of this study is to determine parental perceptions of DKA symptoms in children with type 1 diabetes in the Northern Region of Saudi Arabia. Methods: In the Northern Region of Saudi Arabia, a cross-sectional study was conducted from November 2020 to May 2021 among parents with diabetic children at the Diabetes Center in the Northern Region of Saudi Arabia using a pre-designed online questionnaire distributed on social media web-sites to collect data.  Data was analyzed by using statistical package for the social sciences (SPSS, version 23) and results was presented by tabular and graphical presentation according to the study objectives. Results: only 42.9% of our participants responded that they have good knowledge about DKA. 19.2% thought it only occurs in children. 43.3% of our participants knew that DKA is a complication of diabetes due to hyperglycemia. Regarding the source of information about DKA among our participants, our data demonstrated that only 22.9% of our participants got their information about DKA from the doctors, and 31.8% of the participants had the internet as their source of information regarding DKA. In the current study, 14% of the participants said that they had a child had DKA at least one, and 91.6% of them were admitted to the hospital. There was a significant relation with gender, age of the parent, and educational level, while it showed insignificant relation with marital status. Conclusion: In conclusion, knowledge of most of parents of diabetic children about diabetic ketoacidosis is poor. Their main knowledge source is not trustful or adequate. Their main knowledge source is not trustful or adequate. Therefore, we recommend policy makers to held health education to parents and/or caregivers of type 1 diabetic children regarding all aspects of DKA. It must be properly achieved in a structured manner based on a general outline that should include education at the onset of treatment and then repeated based upon an annual assessment of patients’ training needs or upon their own request. Areas of poor knowledge related to diabetes and diabetic ketoacidosis should be emphasized during health education sessions.


Diabetologia ◽  
1982 ◽  
Vol 22 (4) ◽  
pp. 245-249 ◽  
Author(s):  
G. A. Werther ◽  
R. C. Turner ◽  
P. A. Jenkins ◽  
J. D. Baum

Author(s):  
Zuhrinah Ridwan ◽  
Uleng Bahrun ◽  
Ruland DN Pakasi R

Type 1 Diabetes Mellitus (DMT1) is an autoimmune disease characterized by impaired carbohydrate, protein and lipid metabolismresulting in insulin deficiency either absolute or relative. The absolute insulin deficiency found in DMT1, is caused by a defect in thepancreatic ß cells leading to a defect in insulin synthesis by the pancreas gland. In this article, a case of type 1 DM in a child withketoacidosis diabetes has been reported. The diagnosis was based on classical symptoms, blood glucose level, C-peptide, metabolic acidosisand keton uria. The case reported is a 12 year old girl, with main complaints of 9 kg body weight loss since three (3) years ago. Thepatient always felt hungry, thirsty and was frequently urinating. In her family history no such case was denied. The patient had beentreated in the district general hospitals for five (5) days and was diagnosed as type 1 diabetes mellitus and was then referred to the Dr.Wahidin Sudirohusodo Hospital. The laboratory test results revealed as follows, random glucose level was 729 mg/dL, arterial blood gasanalysis showed metabolic acidosis, C-peptide was 0.1 ng/mL and urinalysis showed 150 mg/dL protein, 1000 mg/dL glucose, 150 mg/dL ketone and 250 RBC/uL. The patient was diagnosed as type 1 diabetes mellitus with diabetic ketoacidosis and received 0.5 U/kg/dayinsulin therapy. This case report aimed to determine the type 1 diabetes mellitus in a child is accompanied by diabetic ketoacidosis.


2020 ◽  
Vol 02 (02) ◽  
Author(s):  
Mona Karem ◽  
Nada Said ◽  
Amina Abdelwahab ◽  
Hassan Shora ◽  
Omar Dessouki

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Omneya I. Youssef ◽  
Samar M. Farid

Cardiac arrest has been described in children with diabetic ketoacidosis (DKA). Aim. To evaluate QTc and QTd in type 1 diabetic children with DKA. Methods. Twelve-lead ECG was done to 30 type 1 diabetic children with DKA at presentation and recovery. Corrected QT interval and QT dispersion (QTd) were assessed. Results. QTc and QTd mean values were significantly decreased in patients after than before DKA recovery (P<0.01). Procedure. Sixteen patients (53, 3%) had prolonged QTc during DKA (range 451–538 ms) that dropped to one patient after recovery, his QTc (453 ms) returned to normal 5 days after hospital discharge. Nineteen patients (63.3%) had prolonged QTd (>50 ms) that dropped to three after recovery. The fact that three patients had normal QTc but prolonged QTd increases the privilege of QTd over QTc as a better marker for cardiac risk in those patients. Anion gap was significantly associated with QTc and QTd prolongation (P<0.0001). Patients had no electrolyte abnormalities or hypoglycemia to account for QTc or QTd prolongation. Conclusion. Prolonged QTc and QTd frequently occur in DKA positively correlated to ketosis. Cardiac monitoring for patients with DKA is mandatory.


2019 ◽  
Vol 38 (7) ◽  
pp. 577-585 ◽  
Author(s):  
Katherine Semenkovich ◽  
Kristoffer S. Berlin ◽  
Rachel L. Ankney ◽  
Kimberly L. Klages ◽  
Mary E. Keenan ◽  
...  

2017 ◽  
Author(s):  
Marwa Omri ◽  
Rayene Ben Mohamed ◽  
Imen Rezgani ◽  
Sana Mhidhi ◽  
Aroua Temessek ◽  
...  

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