Anti-inflammatory and anti-arthritic properties of aqueous extract of Nauclea diderrichii (Rubiaceae) stem bark in rats

2020 ◽  
Vol 20 (2) ◽  
pp. 199-212
Author(s):  
Marius Mbiantcha ◽  
Marcelle Bejoutance Djami ◽  
Gilbert Ateufack ◽  
Donatien Albert Atsamo ◽  
Gonzal Eric Tsafack ◽  
...  
2016 ◽  
Vol 13 (2) ◽  
pp. 83
Author(s):  
Stephen O. Okpo ◽  
Jeffery O. Irivboje ◽  
Chinedu C. Maduekwe ◽  
Joseph O. Idemudia

2000 ◽  
Vol 71 (1-2) ◽  
pp. 275-280 ◽  
Author(s):  
K Saidu ◽  
J Onah ◽  
A Orisadipe ◽  
A Olusola ◽  
C Wambebe ◽  
...  

Author(s):  
Atèhèzi Tougoma ◽  
S. Komi Atchrimi ◽  
Adama Dénou ◽  
V. Oto-Obong Idah ◽  
U. Gideon Egesie ◽  
...  

Author(s):  
Oluwafemi Gabriel Oluwole ◽  
Celestine Esume

AbstractRecent studies in standard laboratories have indicated that a typical mango stem bark aqueous extract (This study investigated the anti-inflammatory effects of the aqueous extract ofRats (n=5) were treated orally with MI (50, 100 and 200 mg/kg), acetylsalicylic acid (100 mg/kg) or distilled water (3 mL). Thirty minutes later, acute inflammation was induced with a sub-plantar injection of 0.1 mL of 1% carrageenin solution into the right hind paw of the rats. The paw oedema sizes were measured with the aid of a Vernier calliper over a period of 3 hours.The aqueous extract of MI (50–200 mg/kg, p.o.) produced a dose-dependent and significant inhibition of the acute inflammation induced by the carrageenin in rats when compared with controls. The percentage inhibition of oedema formation produced by MI (200 mg/kg, p.o.) was similar to that elicited by acetylsalicylic acid (100 mg/kg, p.o.).The results of this preliminary investigation suggest that MI contains active compounds with an anti-inflammatory activity. However, more detailed studies using additional models are necessary to further characterise the effects of MI in inflammatory disorders.


2014 ◽  
Vol 05 (12) ◽  
pp. 1113-1118 ◽  
Author(s):  
Romaric De Garde Elion Itou ◽  
Rokia Sanogo ◽  
Arnaud Wilfrid Etou Ossibi ◽  
Freddy Gelase Nsondé Ntandou ◽  
Radard Ondelé ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document