scholarly journals Late Onset of Neuromyelitis Optica Spectrum Disorders

2019 ◽  
Vol 8 (2) ◽  
pp. 477-482 ◽  
Author(s):  
Yara Dadalti Fragoso ◽  
Heloisa Helena Ruocco ◽  
Ronaldo Maciel Dias ◽  
Hideraldo Cabeça ◽  
Ricardo Gonçalves ◽  
...  
Author(s):  
Keiichi Nakahara ◽  
Shunya Nakane ◽  
Akiko Nagaishi ◽  
Tomoko Narita ◽  
Hidenori Matsuo ◽  
...  

2016 ◽  
Vol 127 (4) ◽  
pp. 334-338 ◽  
Author(s):  
Lin-Jie Zhang ◽  
Li-Na Yang ◽  
Ting Li ◽  
Jing Wang ◽  
Yuan Qi ◽  
...  

2020 ◽  
Vol 267 (5) ◽  
pp. 1260-1268 ◽  
Author(s):  
Edgar Carnero Contentti ◽  
Vanessa Daccach Marques ◽  
Ibis Soto de Castillo ◽  
Verónica Tkachuk ◽  
Bustos Ariel ◽  
...  

2020 ◽  
Author(s):  
Keiichi Nakahara ◽  
Shunya Nakane ◽  
Yukio Ando

Abstract Objective: To clarify the clinical features of very late-onset neuromyelitis optica spectrum disorders NMOSD (VLO-NMOSD).Methods: According to the age at onset, we classified patients with NMOSD into three subgroups of early-onset NMOSD (EO-NMOSD), late-onset NMOSD (LO-NMOSD), and VLO-NMOSD. We evaluated the clinical characteristics, MRI findings, laboratory data, and immunotherapies among the groups.Results: Overall, eight males and 36 females with a median age at onset of 43.00 years (interquartile range, 29.00–54.75) and median duration of disease of 6.00 months (interquartile range, 3.00–11.75) were included. This included 7 (16%) patients with VLO-NMOSD, 11 (25%) with LO-NMOSD, and 26 (59%) with EO-NMOSD. Patients with EO-NMOSD had significantly longer disease duration than those did with VLO-NMOSD and LO-NMOSD (p=0.015). Optic nerve lesions on MRI and optic neuritis were significantly less frequent in patients with VLO-NMOSD than in those with LO-NMOSD and EO-NMOSD (p=0.013 and p=0.046, respectively), whereas the length of the spinal lesion was significantly longer in those with VLO-NMOSD in comparison with those with LO-NMOSD and EO-NMOSD (p=0.038).Conclusions: Spinal cord lesion in patients with VLO-NMOSD was significantly longer despite short disease duration, and optic neuritis was significantly less frequent in them.


2018 ◽  
Author(s):  
Christian Lechner ◽  
Matthias Baumann ◽  
Eva-Maria Hennes ◽  
Kathrin Schanda ◽  
Markus Reindl ◽  
...  

2015 ◽  
Vol 262 (8) ◽  
pp. 1890-1898 ◽  
Author(s):  
Lin-Jie Zhang ◽  
Ning Zhao ◽  
Ying Fu ◽  
Da-Qi Zhang ◽  
Jing Wang ◽  
...  

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