Influence of CYP2D6 Phenotypes on the Pharmacokinetics of Aripiprazole and Dehydro-Aripiprazole Using a Physiologically Based Pharmacokinetic Approach

Physiologically Based ◽

Evaluation of a Physiologically-Based Pharmacokinetic Approach for Simulating the First-Time-In-Animal Study

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/j.1742-7843.2005.pto960321.x ◽

2005 ◽

Vol 96 (3) ◽

pp. 254-256 ◽

Cited By ~ 8

Author(s):

Massimiliano Germani ◽

Patrizia Crivori ◽

Maurizio Rocchetti ◽

Philip S. Burton ◽

Alan G. E. Wilson ◽

...

Keyword(s):

Animal Study ◽

Physiologically Based ◽

First Time ◽

Evaluation of Oral and Intravenous Route Pharmacokinetics, Plasma Protein Binding, and Uterine Tissue Dose Metrics of Bisphenol A: A Physiologically Based Pharmacokinetic Approach

Toxicological Sciences ◽

10.1093/toxsci/kfi135 ◽

2005 ◽

Vol 85 (2) ◽

pp. 823-838 ◽

Cited By ~ 103

Author(s):

Justin G. Teeguarden ◽

John M. Waechter ◽

Harvey J. Clewell ◽

Tammie R. Covington ◽

Hugh A. Barton

Keyword(s):

Bisphenol A ◽

Protein Binding ◽

Plasma Protein Binding ◽

Intravenous Route ◽

Uterine Tissue ◽

Tissue Dose ◽

Physiologically Based ◽

Dose Metrics ◽

Modelling Age-Related Changes in the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone in Different CYP2D6 Phenotypes Using a Physiologically Based Pharmacokinetic Approach

Pharmaceutical Research ◽

10.1007/s11095-020-02843-7 ◽

2020 ◽

Vol 37 (6) ◽

Author(s):

Lisa Alina Kneller ◽

Georg Hempel

Keyword(s):

Age Related ◽

Physiologically Based ◽

Pharmacokinetic Approach ◽

Age Related Changes

Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1541 ◽

2019 ◽

Vol 60 (4) ◽

pp. 477-488

Author(s):

Xuemei Wu ◽

Hongfei Zhang ◽

Mohammad Kowser Miah ◽

Steve N. Caritis ◽

Raman Venkataramanan

Keyword(s):

Physiologically Based ◽

A Novel Experimental and Theoretical Method for Estimating Albumin-Mediated Hepatic Uptake Based on the Albumin Binding Fraction in Plasma and Human PK Prediction Using a Physiologically-Based Pharmacokinetic Approach

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2021.01.015 ◽

2021 ◽

Author(s):

Yu Egashira ◽

Tomoka Shimada ◽

Kei Mayumi

Keyword(s):

Theoretical Method ◽

Hepatic Uptake ◽

Albumin Binding ◽

Physiologically Based ◽

Pharmacokinetic Approach ◽

Human Pk Prediction

Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows-A Physiologically Based Pharmacokinetic Approach

Drug Metabolism and Disposition ◽

10.1124/dmd.115.068858 ◽

2016 ◽

Vol 44 (7) ◽

pp. 1103-1115 ◽

Cited By ~ 5

Author(s):

M. F. Rasool ◽

F. Khalil ◽

S. Laer

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Heart Failure Patients ◽

Blood Flows ◽

Physiologically Based ◽

Pharmacokinetic Approach ◽

Stereoselective Disposition

Successful Prediction of Human Pharmacokinetics by Improving Calculation Processes of Physiologically Based Pharmacokinetic Approach

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2019.03.002 ◽

2019 ◽

Vol 108 (8) ◽

pp. 2718-2727 ◽

Cited By ~ 3

Author(s):

Kei Mayumi ◽

Shuichi Ohnishi ◽

Hiroshi Hasegawa

Keyword(s):

Human Pharmacokinetics ◽

Successful Prediction ◽

Physiologically Based ◽

Investigating the Role of Altered Systemic Albumin Concentration on the Disposition of Theophylline in Adult and Pediatric Patients with Asthma by Using the Physiologically Based Pharmacokinetic Approach

Drug Metabolism and Disposition ◽

10.1124/dmd.120.090969 ◽

2020 ◽

Vol 48 (7) ◽

pp. 570-579

Author(s):

Muhammad Fawad Rasool ◽

Ramsha Khalid ◽

Imran Imran ◽

Abdul Majeed ◽

Hamid Saeed ◽

...

Keyword(s):

Pediatric Patients ◽

Albumin Concentration ◽

Physiologically Based ◽

Correction to “Investigating the Role of Altered Systemic Albumin Concentration on the Disposition of Theophylline in Adult and Pediatric Patients with Asthma by Using the Physiologically Based Pharmacokinetic Approach”

Drug Metabolism and Disposition ◽

10.1124/dmd.120.090969err ◽

2020 ◽

Vol 49 (1) ◽

pp. 120-120

Keyword(s):

Pediatric Patients ◽

Albumin Concentration ◽

Physiologically Based ◽

Altered Buprenorphine Pharmacokinetics during Pregnancy: A Physiologically Based Pharmacokinetic Approach

10.26226/morressier.57d6b2bfd462b8028d88ef76 ◽

2016 ◽

Author(s):

Hari Kalluri

Keyword(s):

Physiologically Based ◽