Clinical Considerations Regarding the Use of Thiopurines in Older Patients with Inflammatory Bowel Disease

Drugs & Aging ◽  
2021 ◽  
Author(s):  
Margalida Calafat ◽  
Míriam Mañosa ◽  
Fiorella Cañete ◽  
Eugeni Domènech
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Older Patients ◽  
Inflammatory Bowel ◽  
Clinical Considerations

scholarly journals Deficits in geriatric assessment associate with disease activity and -burden in older patients with inflammatory bowel disease

2021 ◽  
Author(s):  
Vera E.R. Asscher ◽  
Sanne N. Waars ◽  
Andrea E. van der Meulen-de Jong ◽  
Rogier J.L. Stuyt ◽  
A. Martine C. Baven-Pronk ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Disease Activity ◽  
Geriatric Assessment ◽  
Bowel Disease ◽  
Older Patients ◽  
Inflammatory Bowel

Current overview of opioids in progression of inflammatory bowel disease; pharmacological and clinical considerations

2021 ◽  
Author(s):  
Naser-Aldin Lashgari ◽  
Nazanin Momeni Roudsari ◽  
Nadia Zandi ◽  
Benyamin Pazoki ◽  
Atiyeh Rezaei ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Inflammatory Bowel ◽  
Clinical Considerations

The Efficacy and Safety of Anti-TNF Therapy in Older Patients With Inflammatory Bowel Disease: A Tale of 2 Cities

2017 ◽  
Vol 112 ◽  
pp. S370
Author(s):  
Akriti Saxena ◽  
Bethany H T. Miller ◽  
Ashley S. Freyre ◽  
Alessandra Sorrentino ◽  
Michelle Long ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Older Patients ◽  
Efficacy And Safety ◽  
Inflammatory Bowel

Inflammatory bowel disease in older patients

1994 ◽  
Vol 78 (6) ◽  
pp. 1303-1319 ◽  
Author(s):  
Deborah E. Fleischer ◽  
Ian S. Grimm ◽  
Lawrence S. Friedman
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Older Patients ◽  
Inflammatory Bowel

scholarly journals Medication Utilization and the Impact of Continued Corticosteroid Use on Patient-reported Outcomes in Older Patients with Inflammatory Bowel Disease

2016 ◽  
Vol 22 (6) ◽  
pp. 1435-1441 ◽  
Author(s):  
Matthew Geisz ◽  
Christina Ha ◽  
Michael D. Kappelman ◽  
Christopher F. Martin ◽  
Wenli Chen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Older Patients ◽  
Patient Reported Outcomes ◽  
Medication Utilization ◽  
Patient Reported ◽  
Inflammatory Bowel ◽  
The Impact

scholarly journals Systematic Review: Components of a Comprehensive Geriatric Assessment in Inflammatory Bowel Disease—A Potentially Promising but Often Neglected Risk Stratification

2019 ◽  
Vol 13 (11) ◽  
pp. 1418-1432 ◽  
Author(s):  
Vera E R Asscher ◽  
Felicia V Y Lee-Kong ◽  
Esther D Kort ◽  
Floor J van Deudekom ◽  
Simon P Mooijaart ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Risk Stratification ◽  
Health Outcomes ◽  
Geriatric Assessment ◽  
Bowel Disease ◽  
Comprehensive Geriatric Assessment ◽  
Older Patients ◽  
Adverse Health ◽  
Adverse Health Outcomes ◽  
Inflammatory Bowel

Abstract Background The population of older patients with inflammatory bowel disease [IBD] is increasing. Patient age does not fully account for poor outcomes and its clinical utility for risk stratification is limited. Comprehensive geriatric assessment [CGA], comprising a somatic, functional, mental, and social assessment or frailty, could be a predictor tool. Aims To systematically review literature on the kind of components of a CGA being used in adult IBD patients and the association of these components with adverse health outcomes. Methods An electronic literature search was performed on January 16, 2018, using PubMed, Embase, Web of Science, the Cochrane Library, CENTRAL, Emcare, and PsycINFO. Longitudinal studies relating somatic, functional, mental, and social assessment or frailty to adverse health outcomes during follow-up in IBD patients were included. The Newcastle-Ottawa scale was used to assess individual study quality. Results Of 4080 identified citations, 27 studies were included, reporting 169 associations. Median sample size was 108 patients (interquartile range [IQR] 60–704). No studies performed subgroup analyses on older patients, and the highest mean age reported was 52.7 years. Somatic and functional assessments were used in three studies, mental in 24, and social in five. No study assessed cognitive status, functional performance, or frailty. In 62 associations [36.7%], components of a CGA were significantly associated with adverse health outcome measurements. Conclusions Components of a CGA were associated with adverse health outcomes in IBD patients, but older patients were under-represented. More studies among older patients with IBD are warranted to further establish the clinical impact of a CGA.

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