Management of chronic insomnia using hypnotics: a friend or a foe?

2022 ◽  
Author(s):  
Aniruddha Basu ◽  
Tanmay Joshi ◽  
Arghya Pal ◽  
Ravi Gupta
Keyword(s):  
Chronic Insomnia

Novel Sleep Drug Cuts Chronic Insomnia Without Rebound

2008 ◽  
Vol 41 (22) ◽  
pp. 20
Author(s):  
BRUCE JANCIN
Keyword(s):  
Chronic Insomnia

Evaluation and Management of Chronic Insomnia in Adults

2009 ◽  
Vol 39 (14) ◽  
pp. 32
Author(s):  
NEIL SKOLNIK ◽  
IBRAHIM MIAN
Keyword(s):  
Chronic Insomnia

scholarly journals Help-seeking behavior of young and middle-aged Austrians with chronic insomnia: Results from the 2017 National Sleep Survey

2021 ◽  
pp. 100002
Author(s):  
Stefan Seidel ◽  
Gerhard Klösch ◽  
Anna Kosheleva ◽  
Kyriaki Papantoniou ◽  
Lin Yang ◽  
...  
Keyword(s):  
Help Seeking ◽  
Chronic Insomnia ◽  
Help Seeking Behavior ◽  
Middle Aged ◽  
Seeking Behavior

scholarly journals 0380 Mood And Quality Of Life Of Patients With Chronic Insomnia After Resistance Exercise And Stretching

SLEEP ◽  
2018 ◽  
Vol 41 (suppl_1) ◽  
pp. A145-A145
Author(s):  
C V D’Aurea ◽  
M G Santana ◽  
G S Passos ◽  
S D Youngstedt ◽  
D Poyares ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Resistance Exercise ◽  
Chronic Insomnia

scholarly journals The cerebral mechanism of acupuncture for chronic insomnia with gastrointestinal disorder: protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Wei Peng ◽  
Xiaojuan Hong ◽  
Yaru Huangfu ◽  
Zhao Sun ◽  
Wei Shen ◽  
...  
Keyword(s):  
Rating Scale ◽  
Acupuncture Treatment ◽  
Sham Acupuncture ◽  
Acupuncture Group ◽  
Chronic Insomnia ◽  
Self Rating ◽  
Real Acupuncture ◽  
Gi Symptoms ◽  
Mri Scans ◽  
Multimodal Mri

Abstract Background Many patients with chronic insomnia disorder (CID) have gastrointestinal (GI) symptoms. First-line insomnia medications do not treat GI problems. Acupuncture has a comprehensive regulative action on both CID and GI disorder and is receiving increasing attention. Recent studies indicate that both CID and GI diseases may cause abnormal brain activity. However, the neurological mechanism underlying the effect of acupuncture on such diseases is still unclear. The aim of this study is to explore the pathological mechanisms of CID with GI discomfort, as well as the main response characteristics of acupuncture treatment from multiple perspectives using multimodal magnetic resonance imaging (MRI). Methods A total of 60 participants with CID and GI disorders will be randomly divided into two groups (real acupuncture group and sham acupuncture group; ratio of 1:1). Patients will receive 20 sessions (five sessions per week) of real acupuncture treatment or sham acupuncture treatment. The primary outcome is the aggregate score on the Pittsburgh Sleep Quality Index. Secondary outcomes are scores on the Gastrointestinal Symptom Rating Scale, Self-Rating Anxiety Scale, and Self-Rating Depression Scale. Multimodal MRI scans and clinical assessments will be performed both at baseline and post-treatment. Another 30 age-, sex-, and education-matched healthy subjects will be recruited as controls and will receive MRI scans and clinical evaluations. Discussion This study aims to provide scientific evidence for the mechanism of acupuncture in treating CID with GI disorder using multimodal MRI imaging data on brain structure, function, and metabolism. Trial registration Chinese Clinical Trial Registry, ChiCTR1800017092 (URL: http://www.chictr.org.cn/showproj.aspx?proj=27173). Registered on July 11, 2018.

scholarly journals Association of P10L Polymorphism in Melanopsin Gene with Chronic Insomnia in Mexicans

2021 ◽  
Vol 18 (2) ◽  
pp. 571
Author(s):  
Bianca Ethel Gutiérrez-Amavizca ◽  
Ernesto Prado Montes de Oca ◽  
Jaime Paul Gutiérrez-Amavizca ◽  
Oscar David Castro ◽  
Cesar Heriberto Ruíz-Marquez ◽  
...  
Keyword(s):  
Statistical Power ◽  
Medical Condition ◽  
Severity Index ◽  
Recessive Model ◽  
Chronic Insomnia ◽  
Exact Test ◽  
Fisher's Exact Test ◽  
Increased Risk ◽  
Fisher’S Exact Test ◽  
And Function

The aim of this pilot study was to determine the association of the P10L (rs2675703) polymorphism of the OPN4 gene with chronic insomnia in uncertain etiology in a Mexican population. A case control study was performed including 98 healthy subjects and 29 individuals with chronic insomnia not related to mental disorders, medical condition, medication or substance abuse. Samples were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Genetic analyses showed that the T allele of P10L increased risk to chronic insomnia in a dominant model (p = 1 ×10−4; odds ratio (OR) = 9.37, CI = 8.18–335.66, Kelsey statistical power (KSP) = 99.9%), and in a recessive model (p = 7.5 × 10−5, OR = 9.37, KSP = 99.3%, CI = 2.7–34.29). In the insomnia group, we did not find a correlation between genotypes and chronotype (p = 0.219 Fisher’s exact test), severity of chronic insomnia using ISI score (p = 0.082 Fisher’s exact test) and ESS score (p ˃ 0.999 Fisher’s exact test). However, evening chronotype was correlated to daytime sleepiness severity, individuals with an eveningness chronotype had more severe drowsiness according to their insomnia severity index (ISI) score (p = 0.021 Fisher’s exact test) and Epworth sleepiness scale (ESS) score (p = 0.015 Fisher’s exact test) than the morningness and intermediate chronotype. We demonstrated that the T allele of the P10L polymorphism in the OPN4 gene is associated with chronic insomnia in Mexicans. We suggest the need to conduct larger studies in different ethnic populations to test the probable association and function of P10L and other SNPs in the OPN4 gene and in the onset of chronic insomnia.

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