scholarly journals EuGMS 2019 Congress report: evidence-based medicine in geriatrics

2020 ◽  
Vol 11 (6) ◽  
pp. 915-918
Author(s):  
Suzy V. Hope ◽  
Anastasia Koutsouri ◽  
Sylvain Nguyen ◽  
Karolina Piotrowicz ◽  
Mirko Petrovic ◽  
...  
Keyword(s):  
Older People ◽  
Evidence Based Medicine ◽  
State Of The Art ◽  
Evidence Based ◽  
Life Stages ◽  
European Academy ◽  
Age Related ◽  
Based Medicine ◽  
Congress Report ◽  
Closing Ceremony

AbstractThe 2019 EuGMS Congress “Evidence-Based Medicine in Geriatrics” was held in Krakow, Poland, and attended by over 1600 participants from 64 different countries. A summary and reflection on the congress was presented in the Closing Ceremony by European Academy for Medicine of Aging graduates, and summarised in this article. Keynote lectures, ‘state of the art’ sessions and symposia presented the evidence relating to different age-related conditions, their prevention, management and treatments. Hot topic areas included frailty and multimorbidity, and evidence-based attempts to address these conditions at different life stages. The field of geriatrics represents unique challenges for evidence-based medicine practice. There is much research going on. Clear leadership is needed to facilitate consensus agreements on standard definitions, methods and relevant outcomes, in collaboration with older people themselves, to maximise the opportunities and benefits of doing this research, and benefiting our patients and society at large.

scholarly journals Treatment of macular diseases: an overview of key randomized clinical trials

2022 ◽  
Vol 14 (4) ◽  
pp. 137-148
Author(s):  
E. V. Bobykin ◽  
O. V. Morozova ◽  
N. S. Beresneva
Keyword(s):  
Clinical Trials ◽  
Evidence Based Medicine ◽  
Social Impact ◽  
Randomized Clinical Trials ◽  
Vision Loss ◽  
Age Related Macular Degeneration ◽  
Evidence Based ◽  
Age Related ◽  
Macular Diseases ◽  
Based Medicine

Macular diseases are traditionally a serious issue in ophthalmology, which has great social impact due to widespread occurrence and significant vision loss, often irreversible. Over the past few decades, the possibilities for the diagnosis and treatment of pathologies of the retina and choroid have been significantly expanded. Randomized clinical trials provided ophthalmologists with valuable information on the natural course and treatment strategies of common retinal diseases from the viewpoint of evidence-based medicine. However, due to the large number of trials conducted, it is often difficult to make an adequate choice of data to be used in daily practice. In this review, we systematize the most valuable randomized clinical trials. To this end, we selected 42 randomized clinical studies conducted between 1979 and 2019 and focused on the treatment of age-related macular degeneration (AREDS 1, AREDS 2, ANCHOR, MARINA, PrONTO, CATT, IVAN, VIEW 1, VIEW 2, EVEREST II, PLANET, SEVEN-UP, ALTAIR, HAWK, HARRIER), choroidal neovascularization of multiple etiology (myopic, post-inflammatory, angioid-streak-related, etc. — RADIANCE, REPAIR, MYRROR, MINERVA), diabetic eye lesions (diabetic retinopathy and diabetic macular edema — ETDRS, DRCR.net Protocols B, I, S and T, RISE, RIDE, VIVID-DME, VISTA-DME, MEAD, FAME), retinal vein occlusions (BVOS, CVOS, SCORE-CRVO, SCORE-BRVO, BRAVO, CRUISE, GALILEO, COPERNICUS, VIBRANT), as well as retinopathy of prematurity (CRYO-ROP, ETROP, RAINBOW). The review summarizes the main results of these studies, which confirm the effectiveness and safety of such treatment methods as antiVEGF and photodynamic therapy, retinal laser photocoagulation, cryotherapy, corticosteroids and nutraceuticals from the viewpoint of evidence-based medicine. For greater clarity, we provide a table summarizing information on each of the randomized clinical trials considered.

Polypharmacy and falls in older people: Balancing evidence-based medicine against falls risk

2014 ◽  
Vol 127 (3) ◽  
pp. 330-337 ◽  
Author(s):  
Anam Zia ◽  
Shahrul Bahyah Kamaruzzaman ◽  
Maw Pin Tan
Keyword(s):  
Older People ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Falls Risk ◽  
Based Medicine

Principles of medication management

2017 ◽  
pp. 177-182
Author(s):  
David G. Le Couteur ◽  
Andrew J. McLachlan ◽  
Sarah N. Hilmer
Keyword(s):  
Older People ◽  
Drug Disposition ◽  
Clinical Skills ◽  
Medication Management ◽  
Evidence Based ◽  
Close Monitoring ◽  
Age Related ◽  
The Individual ◽  
Based Medicine ◽  
Related Harm

Older people use numerous medications, yet the evidence for effectiveness in old age is often limited while the evidence for medication-related harm is substantial. Issues common in older people such as multimorbidity, polypharmacy, frailty, dementia, and terminal illnesses influence the decision to prescribe or deprescribe. Age-related changes in drug disposition, coupled with concerns about adverse drug reactions often necessitate lower maintenance doses. Medical ethics and the principles of pharmacokinetics and pharmacodynamics provide overarching frameworks to tailor evidence-based medicine and single disease guidelines to the individual needs and goals of older and frail people. Close monitoring combined with the assumption that any symptom can be medication-related are key clinical skills required for the ongoing optimization of medication use in older people.

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