Amyloid Nephropathy

Keyword(s):  



2018 ◽  
Vol 12 (1) ◽  
Author(s):  
Se-Hee Yoon ◽  
Jang-Hee Cho ◽  
Hee-Yeon Jung ◽  
Won-Min Hwang ◽  
Sung-Ro Yun ◽  
...  


2001 ◽  
Vol 11 (1) ◽  
pp. 36-40
Author(s):  
Sinan Erten ◽  
Meltem Avcı ◽  
Harun Yenice ◽  
Murat Akyurt ◽  
Gül Bozdemir


Blood ◽  
2010 ◽  
Vol 115 (15) ◽  
pp. 2998-3007 ◽  
Author(s):  
Arie J. Stangou ◽  
Nicholas R. Banner ◽  
Bruce M. Hendry ◽  
Mohamed Rela ◽  
Bernard Portmann ◽  
...  

Abstract Variants of fibrinogen A α-chain (AFib) cause the most common type of hereditary renal amyloidosis in Europe and, possibly, the United States as well. Variant fibrinogen is produced in the liver, and solitary renal allografts fail within 1 to 7 years with recurrent amyloidosis. We assessed 22 AFib patients for combined liver and kidney transplantation (LKT) and report the clinical features and outcome. Twenty-one had E526V and 1, the R554L variant. Coronary atherosclerosis was identified in 68% and systemic atheromatosis in 55%. Vascular atheroma excised at endarterectomy and endomyocardial biopsies contained purely variant fibrinogen amyloid. Half had autonomic neuropathy. Six of 9 patients who underwent LKT are alive (67%), with good allograft function and no amyloidosis at median 67 months (range, 33-155 months) of follow-up. Serial technetium-99m–labeled dimercaptosuccinic acid (99mTc-DMSA) renal scintigraphy in 2 cases of preemptive LKT demonstrated preserved native kidney residual function at 5 years. Four explanted livers were used successfully for domino transplantation. Fibrinogen amyloidosis is a systemic amyloid disease with visceral, vascular, cardiac, and neurologic involvement. LKT is curative; however, cardiovascular amyloidosis may preclude this option. Our data encourage evaluation of preemptive solitary liver transplantation early in the course of amyloid nephropathy to prevent hemodialysis and kidney transplantation.





1989 ◽  
Vol 21 (3) ◽  
pp. 339-347 ◽  
Author(s):  
P. Heering ◽  
B. Kutkuhn ◽  
H. Frenzel ◽  
R. P. Linke ◽  
B. Grabensee


2008 ◽  
Vol 28 (1) ◽  
pp. 95-97 ◽  
Author(s):  
Jose A. Gómez-Puerta ◽  
Ricard Cervera ◽  
Concepción Moll ◽  
Manel Solé ◽  
Antonio Collado ◽  
...  


1973 ◽  
Vol 2 (2) ◽  
pp. 177-181
Author(s):  
Lila Pomianowska ◽  
S. Luft ◽  
Maria Kopeć
Keyword(s):  


Renal Failure ◽  
1992 ◽  
Vol 14 (4) ◽  
pp. 555-562 ◽  
Author(s):  
Joshua Shemer ◽  
Moshe Royburt ◽  
Shaltiel Cabili ◽  
Adrian Laina ◽  
Mordechai Pras ◽  
...  
Keyword(s):  


2003 ◽  
Vol 18 (6) ◽  
pp. 521-526 ◽  
Author(s):  
Ayşe Öner ◽  
Özlem Erdoğan ◽  
Gülay Demircin ◽  
Mehmet Bülbül ◽  
Leyla Memiş


Sign in / Sign up

Export Citation Format

Share Document