Expanding the paradigm of the renin-angiotensin system and angiotensin-converting enzyme inhibitors

1994 ◽  
Vol 128 (5) ◽  
pp. 997-1009 ◽  
Author(s):  
Lawrence Greenwald ◽  
Richard C Becker
2016 ◽  
Vol 7 (1) ◽  
pp. 59-64
Author(s):  
T. N Zvereva ◽  
M. V Zykov ◽  
O. L Barbarash

In the article the problem of renal dysfunction in patients with cardiovascular disease is discussed. It describes the basic mechanisms of renal dysfunction and possible ways of influencing them. Including highlights the main classes of drugs that block the renin-angiotensin system aldesteron. The data of several clinical studies confirming the benefits of angiotensin-converting enzyme inhibitors appointment with a dual mechanism of elimination in these patients.


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