Determination of amniotic fluid total phospholipid phosphorus as a test for fetal lung maturity

1973 ◽  
Vol 115 (7) ◽  
pp. 933-941 ◽  
Author(s):  
George H. Nelson
Keyword(s):  
Amniotic Fluid ◽  
Total Phospholipid ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Lung Maturity

Assessment of fetal lung maturity by colorimetric phospholipid determination without digestion.

1979 ◽  
Vol 25 (5) ◽  
pp. 793-796 ◽  
Author(s):  
H G Worth ◽  
D J Wright
Keyword(s):  
Statistical Analysis ◽  
Amniotic Fluid ◽  
Total Phospholipid ◽  
Fetal Lung ◽  
Routine Laboratory ◽  
Fetal Lung Maturity ◽  
Laboratory Results ◽  
Original Procedure ◽  
Lung Maturity

Abstract A previously described method for the determination of phospholipid concentration in amniotic fluid without digestion has been modified to make it more suitable for use in a routine laboratory. Results compare well with those by the original procedure. Results from nearly 70 amniotic fluids, collected at delivery, were compared with lecithin/sphingomyelin (L/S) ratios determined on the same fluids. Statistical analysis of these data showed that for the prediction of lung immaturity, determination of total phospholipid concentration was at least as good as the L/S ratio.

Determination of fetal lung maturity by fluorescence polarization of amniotic fluid

1978 ◽  
Vol 130 (7) ◽  
pp. 782-787 ◽  
Author(s):  
Thomas A. Blumenfeld ◽  
Raymond I. Stark ◽  
L. Stanley James ◽  
John D. George ◽  
Inga Dyrenfurth ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Fluorescence Polarization ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Lung Maturity

scholarly journals DETERMINATION OF FETAL LUNG MATURITY BY FLUORESCENT POLARIZATION (FP) OF AMNIOTIC FLUID

1977 ◽  
Vol 11 (4) ◽  
pp. 413-413 ◽  
Author(s):  
John F Vogt ◽  
Steven A Golde ◽  
Luis A Cabal ◽  
Steven Gabbe ◽  
Joan E Hedgman
Keyword(s):  
Amniotic Fluid ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Lung Maturity

Prediction of Fetal Lung and Kidney Maturity by Determination of Amniotic Fluid Lecithin: Sphingomyelin Ratio and Creatinine Concentration

1974 ◽  
Vol 19 (5) ◽  
pp. 229-232 ◽  
Author(s):  
R. D. Paton ◽  
R. W. Logan ◽  
J. MacVicar
Keyword(s):  
Amniotic Fluid ◽  
Gestational Age ◽  
Fetal Lung ◽  
Creatinine Concentration ◽  
Fetal Lung Maturity ◽  
Wide Range ◽  
Immature Lung ◽  
Lung Maturity ◽  
Lung And Kidney

The ratio of lecithin to sphingomyelin (L/S) in amniotic fluid was assessed in 209 patients on 275 occasions and confirmed to be a useful index of fetal lung maturity. Although low and high ratios were found mainly at early and late gestational ages respectively, lung maturity (L/S ratio ≥ 3:1) occurred at a wide range of ages, from 28 to 40 weeks. The L/S ratio was, therefore, not found to be a useful index of gestational age in individual cases. In 174 cases, in addition to determining the L/S ratio, the concentration of creatinine in the liquor was estimated as an index of renal maturity. (Creatinine ≥ 1.6 mg./100 ml. ≡ renal maturity). In 80 per cent of cases, lung and kidney were judged to be both mature or both immature. In the remainder, combinations of mature kidney/immature lung or immature kidney/mature lung existed. Liquor creatinine estimation remains useful as a guide to gestational age and as an adjunct to lung maturity studies.

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