Age-Related Changes in the Extracellular Matrix of the Human Optic Nerve Head

1989 ◽  
Vol 107 (5) ◽  
pp. 476-484 ◽  
Author(s):  
M. Rosario Hernandez ◽  
Xing Xing Luo ◽  
Wieslawa Andrzejewska ◽  
Arthur H. Neufeld
Keyword(s):  
Extracellular Matrix ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Age Related ◽  
Human Optic Nerve ◽  
Age Related Changes

Age-related changes in the human optic nerve

2002 ◽  
Vol 37 (7) ◽  
pp. 389-394 ◽  
Author(s):  
Carlo Cavallotti ◽  
Elena Pacella ◽  
Nicola Pescosolido ◽  
Francesca Maria Tranquilli-Leali ◽  
Janos Feher
Keyword(s):  
Optic Nerve ◽  
Age Related ◽  
Human Optic Nerve ◽  
Age Related Changes

Age-Related Topographical Changes in the Normal Human Optic Nerve Head Measured by Scanning Laser Tomography

2001 ◽  
Vol 78 (6) ◽  
pp. 431-435 ◽  
Author(s):  
HÉLÈNE KERGOAT ◽  
MARIE-JEANNE KERGOAT ◽  
LISETTE JUSTINO ◽  
and JOHN V. LOVASIK
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Scanning Laser ◽  
Laser Tomography ◽  
Age Related ◽  
Normal Human ◽  
Human Optic Nerve

Extracellular Matrix of the Human Optic Nerve Head

1986 ◽  
Vol 102 (2) ◽  
pp. 139-148 ◽  
Author(s):  
M. Rosario Hernandez ◽  
Frank Igoe ◽  
Arthur H. Neufeld
Keyword(s):  
Extracellular Matrix ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Human Optic Nerve

Statins reduce TGF-beta2-modulation of the extracellular matrix in cultured astrocytes of the human optic nerve head

2017 ◽  
Vol 164 ◽  
pp. 55-63 ◽  
Author(s):  
Mi-Lyang Kim ◽  
Kyung Rim Sung ◽  
Jin A. Shin ◽  
Joo Young Yoon ◽  
Joonhee Jang
Keyword(s):  
Extracellular Matrix ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Cultured Astrocytes ◽  
Human Optic Nerve

Parapapillary atrophy in optic neuropathies: Histology and clinical relevance

2021 ◽  
pp. 112067212110606
Author(s):  
Ana Banc ◽  
Stefania Bianchi Marzoli
Keyword(s):  
Optic Nerve ◽  
Optic Neuropathy ◽  
Optic Nerve Head ◽  
Clinical Findings ◽  
Age Related Macular Degeneration ◽  
Glaucomatous Optic Neuropathy ◽  
Age Related ◽  
High Resolution Images ◽  
Parapapillary Atrophy ◽  
Optic Nerve Disorders

Parapapillary atrophy is one of the parameters of the optic nerve head area which are assessed during the ophthalmoscopic examination particularly useful to characterize glaucomatous optic neuropathy. Optical coherence tomography evaluation provides high-resolution images of the optic nerve head and surrounding area, and can be used to study parapapillary atrophy. Different parapapillary atrophy zones were described depending on their histological features and research has been conducted to investigate the possible association between the presence and/ or size of parapapillary atrophy zones and several optic nerve disorders. In this review we discuss the histology and the clinical findings related to parapapillary atrophy in patients with glaucomatous optic neuropathy, non-glaucomatous optic neuropathies (e.g. arteritic and non-arteritic anterior ischemic optic neuropathies; suprasellar and parasellar tumors), and other ocular conditions (e.g. high myopia; age-related macular degeneration). Two different histologic classifications were identified. Parapapillary atrophy was demonstrated in glaucoma and glaucoma-like neuropathies, but not in other types of optic nerve disorders.

scholarly journals Microvascular Density Is Associated With Retinal Ganglion Cell Axonal Volume in the Laminar Compartments of the Human Optic Nerve Head

2018 ◽  
Vol 59 (3) ◽  
pp. 1562 ◽  
Author(s):  
Min H. Kang ◽  
Mengchen Suo ◽  
Chandrakumar Balaratnasingam ◽  
Paula K. Yu ◽  
William H. Morgan ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Nerve Head ◽  
Microvascular Density ◽  
Retinal Ganglion ◽  
Human Optic Nerve
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